Search Results - "REDDISH, M. A"

The effect of feeding a dry enzyme mixture with fibrolytic activity on the performance of lactating cows and digestibility of a diet for sheep by Reddish, M A, Kung, Jr, L

“…A dry enzyme mixture was added to the diets of lactating cows and growing lambs to evaluate its ability to improve milk production and nutrient digestibility,…”
Get more information

Clinical outcome of breast and ovarian cancer patients treated with high-dose chemotherapy, autologous stem cell rescue and THERATOPE® STn-KLH cancer vaccine by HOLMBERG, L. A, OPARIN, D. V, GOOLEY, T, LILLEBY, K, BENSINGER, W, REDDISH, M. A, MACLEAN, G. D, LONGENECKER, B. M, SANDMAIER, B. M

“…The purpose of this study was to evaluate the toxicity and potential efficacy of administering the THERATOPE STn-KLH cancer vaccine to ovarian and breast…”
Get full text

Antibodies against mucin-associated sialyl-Tn epitopes correlate with survival of metastatic adenocarcinoma patients undergoing active specific immunotherapy with synthetic STn vaccine by MacLean, G D, Reddish, M A, Koganty, R R, Longenecker, B M

“…The humoral immune response of 85 metastatic breast, ovarian, and colorectal cancer patients was analyzed after immunization with THERATOPE STn-KLH (KLH,…”
Get more information

Enhancing the effect of THERATOPE STn-KLH cancer vaccine in patients with metastatic breast cancer by pretreatment with low-dose intravenous cyclophosphamide by MacLean, G D, Miles, D W, Rubens, R D, Reddish, M A, Longenecker, B M

“…THERATOPE (Biomira Inc., Edmonton, AB, Canada) STn-KLH cancer vaccine induces strong antibody titers against both the synthetic STn epitope and against a…”
Get more information

Safety and Immunogenicity of 26-Valent Group A Streptococcus Vaccine in Healthy Adult Volunteers by McNeil, Shelly A., Halperin, Scott A., Langley, Joanne M., Smith, Bruce, Warren, Andrew, Sharratt, Geoffrey P., Baxendale, Darlene M., Reddish, Mark A., Hu, Mary C., Stroop, Steven D., Linden, Janine, Fries, Louis F., Vink, Peter E., Dale, James B.

“…Background. Group A streptococcus (GAS) causes illness ranging from uncomplicated pharyngitis to life-threatening necrotizing fasciitis, toxic shock, and…”
Get full text

Evidence of a cellular immune response against sialyl-Tn in breast and ovarian cancer patients after high-dose chemotherapy, stem cell rescue, and immunization with Theratope STn-KLH cancer vaccine by Sandmaier, B M, Oparin, D V, Holmberg, L A, Reddish, M A, MacLean, G D, Longenecker, B M

“…Seven ovarian and 33 breast high-risk stage II/III and stage IV cancer patients received high-dose chemotherapy followed by stem cell rescue. Thirty to 151…”
Get more information

Immunogenicity and antitumor activity of a liposomal MUC1 peptide‐based vaccine by Samuel, John, Budzynski, Wladyslaw A., Reddish, Mark A., Ding, Lei, Zimmermann, Gabrielle L., Krantz, Mark J., Koganty, R. Rao, Longenecker, B. Michael

“…A human MUC1‐transfected mouse mammary adenocarcinoma cell line (GZHI) was used to develop both subcutaneous and intravenous tumor models. A vaccine…”
Get full text

Vaccines prepared with sialyl-Tn and sialyl-Tn trimers using the 4-(4-maleimidomethyl)cyclohexane-1-carboxyl hydrazide linker group result in optimal antibody titers against ovine submaxillary mucin and sialyl-Tn-positive tumor cells by RAGUPATHI, G, HOWARD, L, CAPPELLO, S, RAO KOGANTY, R, DONGXU QIU, LONGENECKER, B. M, REDDISH, M. A, LLOYD, K. O, LIVINGSTON, P. O

“…Sialyl-Tn (STn) is an O-serine- or O-threonine-linked disaccharide [NeuAcalpha(2-->6)GalNAcalpha-O-Ser/Thr) expressed on mucins of most types of adenocarcinoma…”
Get full text

Rapid induction of primary human CD4+ and CD8+ T cell responses against cancer-associated MUC1 peptide epitopes by Agrawal, B, Krantz, M J, Reddish, M A, Longenecker, B M

“…Antigen-specific MHC class II- and class I-restricted helper and cytotoxic T cell responses are important anti-cancer immune responses. MUC1 mucin is a…”
Get full text

Pre-immunotherapy serum CA27.29 (MUC-1) mucin level and CD69+ lymphocytes correlate with effects of Theratope® sialyl-Tn-KLH cancer vaccine in active specific immunotherapy by REDDISH, M. A, MACLEAN, G. D, POPPEMA, S, BERG, A, LONGENECKER, B. M

“…Patients with metastatic breast, colorectal or ovarian cancers received active specific immunotherapy (ASI) with Theratope sialyl-Tn-KLH (keyhole limpet…”
Get full text

Does pregnancy immunize against breast cancer ? by AGRAWAL, B, REDDISH, M. A, KRANTZ, M. J, LONGENECKER, B. M

“…Multiparity has been linked with protection against breast cancer. T cells from biparous women, but not T cells from nulliparous women or men, specifically…”
Get full text

CD69+ and HLA-DR+ activation antigens on peripheral blood lymphocyte populations in metastatic breast and ovarian cancer patients: correlations with survival following active specific immunotherapy by Yacyshyn, M B, Poppema, S, Berg, A, MacLean, G D, Reddish, M A, Meikle, A, Longenecker, B M

“…Lymphocyte activation markers CD69 and HLA-DR were studied in metastatic breast and ovarian cancer patients who received active specific immunotherapy (ASI)…”
Get more information

The anti-MUC1 monoclonal antibody BCP8 can be used to isolate and identify putative major histocompatibility complex class I associated amino acid sequences by AGRAWAL, B, REDDISH, M. A, CHRISTIAN, B, VANHEELE, A, LEON TANG, RAO KOGANTY, R, LONGENECKER, B. M

“…MHC class I molecules were isolated from the MUC1-positive human breast adenocarcinoma cell line MCF-7 by immunoaffinity using the panreactive anti-class I…”
Get full text

Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2 by Agrawal, Babita, Krantz, Mark J, Reddish, Mark A, Longenecker, B. Michael

“…A number of adenocarcinomas abundantly express and secrete underglycosylated MUC1 mucin. Underglycosylation exposes tandem repeat peptide sequences on…”
Get full text

The breast mucin MUC1 as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer by REGIMBALD, L. H, PILARSKI, L. M, LONGENECKER, B. M, REDDISH, M. A, ZIMMERMANN, G, HUGH, J. C

Get full text

Expression of mucin genes and carbohydrate epitopes in 19 human colon carcinoma cell lines by Iida, S, Tsuiji, H, Nemoto, Y, Sano, Y, Reddish, M A, Irimura, T

“…The levels of mRNA corresponding to the MUC1, MUC2, MUC5AC, MUC5B, and MUC6 genes were determined in 19 human colon adenocarcinoma cell lines by the reverse…”
Get more information

Anti‐MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide by Reddish, Mark A., MacLean, Grant D., Koganty, R. Rao, Kan‐Mitchell, June, Jones, Vicky, Mitchell, Malcolm S., Longenecker, B. Michael

“…Sixteen metastatic breast cancer patients were immunized with a low dose (5 μg) of a 16 amino acid MUC1 peptide (GVTSAPDTRPAPGSTA) conjugated to KLH (BP16‐KLH)…”
Get full text

In vitro induction of MUC-1 peptide-specific type 1 T lymphocyte and cytotoxic T lymphocyte responses from healthy multiparous donors by Agrawal, B, Reddish, MA, Longenecker, BM

“…We have recently provided evidence that there is a natural immunization against human cancer-associated MUC-1 mucin epitopes during pregnancy by studying MUC-1…”
Get full text

Liposomal Formulations of Synthetic MUC1 Peptides:  Effects of Encapsulation versus Surface Display of Peptides on Immune Responses by Guan, Holly H, Budzynski, Wladyslaw, Koganty, R. Rao, Krantz, Mark J, Reddish, Mark A, Rogers, James A, Longenecker, B. Michael, Samuel, John

“…Synthetic human MUC1 peptides are important candidates for therapeutic cancer vaccines. To explore whether a human MUC1 peptide BP25…”
Get full text

Histamine-induced suppressor factor (HSF): inhibition of helper T cell generation and function by Garovoy, MR, Reddish, MA, Rocklin, RE

“…The effect of histamine-induced suppressor factor (HSF) on the humoral immune response was examined with the model of polyclonal B cell activation induced…”
Get full text