Search Results - "REBECCA LONGBOTTOM, E"

Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery by Torrance, Hew D T, Longbottom, E Rebecca, Vivian, Mark E, Lalabekyan, Bagrat, Abbott, Tom E F, Ackland, Gareth L, Hinds, Charles J, Pearse, Rupert M, O'Dwyer, Michael J

“…Post-operative infections occur frequently following major surgery. The magnitude of the post-operative immune response is associated with an increased risk of…”
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Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells by NOORDEEN, Nafeesa A, KHERA, Tarnjit K, GAO SUN, REBECCA LONGBOTTOM, E, PULLEN, Timothy J, DA SILVA XAVIER, Gabriela, RUTTER, Guy A, LECLERC, Isabelle

“…Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells Nafeesa A. Noordeen…”
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Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways by Longbottom, E Rebecca, Torrance, Hew D T, Owen, Helen C, Fragkou, Paraskevi C, Hinds, Charles J, Pearse, Rupert M, O'Dwyer, Michael J

“…The aim of this study was to evaluate the role of interleukin (IL)-6 pathways in postoperative immune suppression and to assess the reversibility of this…”
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A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery by Torrance, Hew D, Zhang, Ping, Longbottom, E Rebecca, Mi, Yuxin, Whalley, Justin P, Allcock, Alice, Kwok, Andrew J, Cano-Gamez, Eddie, Geoghegan, Cyndi G, Burnham, Katie L, Antcliffe, David B, Davenport, Emma E, Pearse, Rupert M, O’Dwyer, Michael J, Hinds, Charles J, Knight, Julian C, Gordon, Anthony C

“…To describe immune pathways and gene networks altered following major abdominal surgery and to identify transcriptomic patterns associated with postoperative…”
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Positive Feedback Regulation between γ-Aminobutyric Acid Type A (GABAA) Receptor Signaling and Brain-derived Neurotrophic Factor (BDNF) Release in Developing Neurons by Porcher, Christophe, Hatchett, Caroline, Longbottom, Rebecca E., McAinch, Kristina, Sihra, Talvinder S., Moss, Stephen J., Thomson, Alex M., Jovanovic, Jasmina N.

“…During the early development of the nervous system, γ-aminobutyric acid (GABA) type A receptor (GABAAR)-mediated signaling parallels the…”
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Risk factors for admission at three urban emergency departments in England: a cross-sectional analysis of attendances over 1 month by Ismail, Sharif A, Pope, Ian, Bloom, Benjamin, Catalao, Raquel, Green, Emilie, Longbottom, Rebecca E, Jansen, Gwyneth, McCoy, David, Harris, Tim

“…ObjectiveTo investigate factors associated with unscheduled admission following presentation to emergency departments (EDs) at three hospitals in…”
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ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile by Barrow, Stephanie L., Voronina, Svetlana G., da Silva Xavier, Gabriela, Chvanov, Misha A., Longbottom, Rebecca E., Gerasimenko, Oleg V., Petersen, Ole H., Rutter, Guy A., Tepikin, Alexei V.

“…Here, we describe novel mechanisms limiting a toxic cytosolic Ca 2+ rise during adenosine 5′-triphosphate (ATP) depletion. We studied the effect of ATP…”
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Carbohydrate-responsive element-binding protein is a negative regulator of ARNT/HIF-1[beta] gene expression in pancreatic islet [beta]-cells by Noordeen, Nafeesa A, Khera, Tarnjit K, Sun, Gao, Longbottom, E. Rebecca, Pullen, Timothy J, Xavier, Gabriela da Silva, Rutter, Guy A, Leclerc, Isabelle

“…OBJECTIVE--Carbohydrate-responsive element-binding protein (ChREBP) is a transcription factor that has been shown to regulate carbohydrate metabolism in the…”
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Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells by Noordeen, Nafeesa A, Khera, Tarnjit K, Sun, Gao, Longbottom, E Rebecca, Pullen, Timothy J, da Silva Xavier, Gabriela, Rutter, Guy A, Leclerc, Isabelle

“…Carbohydrate-responsive element-binding protein (ChREBP) is a transcription factor that has been shown to regulate carbohydrate metabolism in the liver and…”
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Distribution of the voltage-dependent calcium channel alpha(1A) subunit throughout the mature rat brain and its relationship to neurotransmitter pathways by Craig, P J, McAinsh, A D, McCormack, A L, Smith, W, Beattie, R E, Priestley, J V, Yip, J L, Averill, S, Longbottom, E R, Volsen, S G

“…The alpha(1) subunit provides both the voltage-sensing mechanism and the ion pore of voltage-dependent calcium channels. Of the six classes of alpha(1) subunit…”
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Distribution of the voltage-dependent calcium channel α1A subunit throughout the mature rat brain and its relationship to neurotransmitter pathways by Craig, Peter J., McAinsh, Andrew D., McCormack, Alison L., Smith, William, Beattie, Ruth E., Priestley, John V., Yip, Jennifer Lai Yee, Averill, Sharon, Longbottom, E. Rebecca, Volsen, Stephen G.

“…The α1 subunit provides both the voltage‐sensing mechanism and the ion pore of voltage‐dependent calcium channels. Of the six classes of α1 subunit cloned to…”
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Distribution of the voltage‐dependent calcium channel α 1A subunit throughout the mature rat brain and its relationship to neurotransmitter pathways by Craig, Peter J., McAinsh, Andrew D., McCormack, Alison L., Smith, William, Beattie, Ruth E., Priestley, John V., Yip, Jennifer Lai Yee, Averill, Sharon, Longbottom, E. Rebecca, Volsen, Stephen G.

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