Search Results - "RAY, Patricio"
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1
Role of rh-IGF-1/IGFBP-3 in the postnatal kidney maturation of preterm pigs: Not so simple
Published in Pediatric research (12-08-2024)Get full text
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2
Continuous kidney replacement therapy in critically ill children: heparin vs citrate
Published in Pediatric research (13-05-2024)Get full text
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3
Acute kidney injury during the first week of life: time for an update?
Published in Pediatric nephrology (Berlin, West) (01-09-2024)Get full text
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4
A new approach to define acute kidney injury in term newborns with hypoxic ischemic encephalopathy
Published in Pediatric nephrology (Berlin, West) (01-07-2016)“…Background Current definitions of acute kidney injury (AKI) are not sufficiently sensitive to identify all newborns with AKI during the first week of life…”
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APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death
Published in Journal of the American Society of Nephrology (01-04-2017)“…People of African ancestry carrying certain APOL1 mutant alleles are at elevated risk of developing renal diseases. However, the mechanisms underlying…”
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6
Clinical practice guideline for the management of chronic kidney disease in patients infected with HIV: 2014 update by the HIV Medicine Association of the Infectious Diseases Society of America
Published in Clinical infectious diseases (01-11-2014)“…It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment…”
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7
Circulating Fibroblast Growth Factor-2, HIV-Tat, and Vascular Endothelial Cell Growth Factor-A in HIV-Infected Children with Renal Disease Activate Rho-A and Src in Cultured Renal Endothelial Cells
Published in PloS one (20-04-2016)“…Renal endothelial cells (REc) are the first target of HIV-1 in the kidney. The integrity of REc is maintained at least partially by heparin binding growth…”
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8
Association of circulating fibroblast growth factor-2 with progression of HIV-chronic kidney diseases in children
Published in Pediatric nephrology (Berlin, West) (01-12-2021)“…Background Children living with HIV frequently show high plasma levels of fibroblast growth factor-2 (FGF-2/bFGF). FGF-2 accelerates the progression of several…”
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Childhood HIV-associated nephropathy: 36 years later
Published in Pediatric nephrology (Berlin, West) (01-08-2021)“…HIV-associated nephropathy (HIVAN) predominantly affects people of African ancestry living with HIV who do not receive appropriate antiretroviral therapy…”
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A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation
Published in Journal of the American Society of Nephrology (01-09-2017)“…Clinical studies have identified patients with nephrotic syndrome caused by mutations in genes involved in the biosynthesis of coenzyme Q 10 (CoQ 10 ), a lipid…”
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11
A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome
Published in Human molecular genetics (15-02-2017)“…Many genetic mutations have been identified as monogenic causes of nephrotic syndrome (NS), but important knowledge gaps exist in the roles of these genes in…”
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12
APOL1-G2 accelerates nephrocyte cell death by inhibiting the autophagy pathway
Published in Disease models & mechanisms (01-12-2023)“…People of African ancestry who carry the APOL1 risk alleles G1 or G2 are at high risk of developing kidney diseases through not fully understood mechanisms…”
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13
Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice
Published in Disease models & mechanisms (01-07-2021)“…People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with…”
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14
Blood Pressure Control by a Secreted FGFBP1 (Fibroblast Growth Factor–Binding Protein)
Published in Hypertension (Dallas, Tex. 1979) (01-01-2018)“…Fibroblast growth factors (FGFs) participate in organ development and tissue maintenance, as well as the control of vascular function. The paracrine-acting…”
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15
Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease
Published in FEBS letters (05-04-2012)“…► Elevated expression of ApoL1 induces autophagy, lysosomal swelling, and cell death. ► The G1 and G2 alleles of APOL1 are associated with CKD in people of…”
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16
A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes
Published in Cell & bioscience (04-11-2023)“…People of Sub-Saharan African ancestry are at higher risk of developing chronic kidney disease (CKD), attributed to the Apolipoprotein L1 (APOL1) gene risk…”
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17
Transmembrane TNF- α Facilitates HIV-1 Infection of Podocytes Cultured from Children with HIV-Associated Nephropathy
Published in Journal of the American Society of Nephrology (01-03-2017)“…Studies have shown that podocytes and renal tubular epithelial cells from patients with HIV-associated nephropathy (HIVAN) express HIV-1 transcripts,…”
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An HIV-Tat inducible mouse model system of childhood HIV-associated nephropathy
Published in Disease models & mechanisms (01-10-2020)“…Modern antiretroviral therapies (ART) have decreased the prevalence of HIV-associated nephropathy (HIVAN). Nonetheless, we continue to see children and…”
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HIV-associated nephropathy: a diagnosis in evolution
Published in Nephrology, dialysis, transplantation (01-11-2012)“…HIV-1 associated nephropathy (HIVAN) is a clinical and renal histological disease characterized by the presence of heavy proteinuria associated with focal…”
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Can we cure HIV-1-associated nephropathy in transgenic mice?
Published in Kidney international (01-05-2012)“…HIV-1-associated nephropathy (HIVAN) is a rapidly progressive form of focal segmental glomerulosclerosis. HIV transgenic mice can develop a HIVAN-like renal…”
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