Search Results - "RAY, Kathryn J"
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High-throughput sequencing of pooled samples to determine community-level microbiome diversity
Published in Annals of epidemiology (01-11-2019)“…Community-level interventions in cluster randomized controlled trials may alter the gut microbiome of individuals. The current method of estimating community…”
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2
Gut Bifidobacteria enrichment following oral Lactobacillus-supplementation is associated with clinical improvements in children with cystic fibrosis
Published in BMC pulmonary medicine (28-07-2022)“…Relationships between gut microbiomes and airway immunity have been established in murine and human studies of allergy and asthma. Early life Lactobacillus…”
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Association between In Vitro Susceptibility to Natamycin and Voriconazole and Clinical Outcomes in Fungal Keratitis
Published in Ophthalmology (Rochester, Minn.) (01-08-2014)“…Purpose To assess the association between minimum inhibitory concentration (MIC) and clinical outcomes in a fungal keratitis clinical trial. Design…”
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Safety of azithromycin in infants under six months of age in Niger: A community randomized trial
Published in PLoS neglected tropical diseases (01-11-2018)“…Mass azithromycin distribution reduces under-5 child mortality. Trachoma control programs currently treat infants aged 6 months and older. Here, we report…”
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Incidence of Herpes Zoster Ophthalmicus: Results from the Pacific Ocular Inflammation Study
Published in Ophthalmology (Rochester, Minn.) (01-03-2013)“…Purpose To provide a population-based estimate of the incidence of herpes zoster ophthalmicus (HZO) with comparisons across racial, sex, and age groups, as…”
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Linear growth in preschool children treated with mass azithromycin distributions for trachoma: A cluster-randomized trial
Published in PLoS neglected tropical diseases (01-06-2019)“…Mass azithromycin distributions have been shown to reduce mortality among pre-school children in sub-Saharan Africa. It is unclear what mediates this mortality…”
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Comparison of annual versus twice-yearly mass azithromycin treatment for hyperendemic trachoma in Ethiopia: a cluster-randomised trial
Published in The Lancet (British edition) (2012)“…Summary Background In trachoma control programmes, azithromycin is distributed to treat the strains of chlamydia that cause ocular disease. We aimed to compare…”
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Assessment of herd protection against trachoma due to repeated mass antibiotic distributions: a cluster-randomised trial
Published in The Lancet (British edition) (28-03-2009)“…Summary Background Trachoma-control programmes distribute oral azithromycin to treat the ocular strains of chlamydia that cause the disease and to control…”
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9
Visual Recovery in Treated Bacterial Keratitis
Published in Ophthalmology (Rochester, Minn.) (01-06-2014)“…Bacterial keratitis is a leading cause of visual impairment worldwide. However, the natural history of treated bacterial keratitis has not been well…”
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10
Effect of the one-child policy on influenza transmission in China: a stochastic transmission model
Published in PloS one (06-02-2014)“…China's one-child-per-couple policy, introduced in 1979, led to profound demographic changes for nearly a quarter of the world's population. Several decades…”
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Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa
Published in The New England journal of medicine (26-04-2018)“…Childhood mortality remains high in sub-Saharan Africa. In this cluster-randomized, placebo-controlled trial, mortality among children younger than 5 years of…”
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Cross-Linking-Assisted Infection Reduction: A Randomized Clinical Trial Evaluating the Effect of Adjuvant Cross-Linking on Outcomes in Fungal Keratitis
Published in Ophthalmology (Rochester, Minn.) (01-02-2020)“…To determine if there is a benefit to adjuvant corneal crosslinking (CXL) and to compare natamycin versus amphotericin B for filamentous fungal keratitis…”
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Assessment of transmission in trachoma programs over time suggests no short-term loss of immunity
Published in PLoS neglected tropical diseases (2013)“…Trachoma programs have dramatically reduced the prevalence of the ocular chlamydia that cause the disease. Some have hypothesized that immunity to the…”
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Latrine Promotion for Trachoma: Assessment of Mortality from a Cluster-Randomized Trial in Ethiopia
Published in The American journal of tropical medicine and hygiene (01-09-2011)“…Trachoma control strategies, including latrine construction and antibiotic distribution, are directed at reducing ocular chlamydia, but may have additional…”
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Effect of Oral Voriconazole on Fungal Keratitis in the Mycotic Ulcer Treatment Trial II (MUTT II): A Randomized Clinical Trial
Published in JAMA ophthalmology (01-12-2016)“…To compare oral voriconazole with placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. The Mycotic Ulcer Treatment…”
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The efficacy of oral azithromycin in clearing ocular chlamydia: Mathematical modeling from a community-randomized trachoma trial
Published in Epidemics (01-03-2014)“…Highlights • We monitored ocular chlamydial infection twice a year in pre-school children in 32 communities in Tanzania. • We used a mathematical transmission…”
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The mycotic ulcer treatment trial: a randomized trial comparing natamycin vs voriconazole
Published in JAMA ophthalmology (01-04-2013)“…To compare topical natamycin vs voriconazole in the treatment of filamentous fungal keratitis. This phase 3, double-masked, multicenter trial was designed to…”
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The epidemiological dynamics of infectious trachoma may facilitate elimination
Published in Epidemics (01-06-2011)“…Abstract Introduction Trachoma programs use mass distributions of oral azithromycin to treat the ocular strains of Chlamydia trachomatis that cause the…”
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When can antibiotic treatments for trachoma be discontinued? Graduating communities in three African countries
Published in PLoS neglected tropical diseases (16-06-2009)“…Repeated mass azithromycin distributions are effective in controlling the ocular strains of chlamydia that cause trachoma. However, it is unclear when…”
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A rationale for continuing mass antibiotic distributions for trachoma
Published in BMC infectious diseases (07-08-2007)“…The World Health Organization recommends periodic mass antibiotic distributions to reduce the ocular strains of chlamydia that cause trachoma, the world's…”
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