Search Results - "RAVINGEROVA, T"

Pleiotropic, non-cell death-associated effects of inhibitors of receptor-interacting protein kinase 1 in the heart by Horvath, C., Szobi, A., Kindernay, L., Ravingerova, T., Adameova, A.

“…Inhibition of receptor-interacting protein kinase 1 (RIP1) has been recognized as a compelling tool for limiting necroptosis. Recent findings have indicated…”
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Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals by Slezák, J, Kura, B, Frimmel, K, Zálešák, M, Ravingerová, T, Viczenczová, C, Okruhlicová, Ľ, Tribulová, N

“…Excessive production of oxygen free radicals has been regarded as a causative common denominator of many pathological processes in the animal kingdom. Hydroxyl…”
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Cardioprotective effects of quercetin against ischemia-reperfusion injury are age-dependent by Bartekova, M, Radosinska, J, Pancza, D, Barancik, M, Ravingerova, T

“…Quercetin, a polyphenolic compound present in various types of food, has been shown to exert beneficial effects in different cardiac as well as non-cardiac…”
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Hyperosmotic environment blunts effectivity of ischemic preconditioning against ischemia-reperfusion injury and improves ischemic tolerance in non-preconditioned isolated rat hearts by Zálešák, M, BlaŽíček, P, Pancza, D, Gablovský, I, Štrbák, V, Ravingerová, T

“…Several studies have shown that diabetes mellitus modulates heart resistance to ischemia and abrogates effectivity of cardioprotective interventions, such as…”
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Voluntary exercise may activate components of pro-survival risk pathway in the rat heart and potentially modify cell proliferation in the myocardium by Lonek, L, Puhova, A, Griecsova-Kindernay, L, Patel, S P, Zohdi, V, Jezova, D, Ravingerova, T

“…Although physical exercise is known to reduce size of infarction, incidence of ventricular arrhythmias, and to improve heart function, molecular mechanisms of…”
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Oxidative stress plays an important role in zoledronic acid-induced autophagy by Khandelwal, V K M, Mitrofan, L M, Hyttinen, J M T, Chaudhari, K R, Buccione, R, Kaarniranta, K, Ravingerová, T, Mönkkönen, J

“…Several pre-clinical and clinical studies have demonstrated zoledronic acid (Zol), which regulates the mevalonate pathway, has efficient anti-cancer effects…”
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Dual influence of spontaneous hypertension on membrane properties and ATP production in heart and kidney mitochondria in rat: effect of captopril and nifedipine, adaptation and dysadaptation by Ziegelhöffer, A, Mujkošová, J, Ferko, M, Vrbjar, N, Ravingerová, T, Uličná, O, Waczulíková, I, Ziegelhöffer, B

“…This study deals with changes, induced by hypertension and its treatment, in the function and properties of mitochondria in the heart and kidneys. Male,…”
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Effect of maturation on the resistance of rat hearts against ischemia. Study of potential molecular mechanisms by Griecsová, L, Farkašová, V, Gáblovský, I, Khandelwal, V K M, Bernátová, I, Tatarková, Z, Kaplan, P, Ravingerová, T

“…Reduced tolerance to ischemia/reperfusion (IR) injury has been shown in elder human and animal hearts, however, the onset of this unfavorable phenotype and…”
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Cardioprotection induced by remote ischemic preconditioning preserves the mitochondrial respiratory function in acute diabetic myocardium by Kancirová, I, Jašová, M, Muráriková, M, Sumbalová, Z, Uličná, O, Ravingerová, T, Waczulíková, I, Ziegelhöffer, A, Ferko, M

“…A 2×2 factorial design was used to evaluate possible preservation of mitochondrial functions in two cardioprotective experimental models, remote ischemic…”
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Remote ischemic preconditioning of the heart: protective responses in functional and biophysical properties of cardiac mitochondria by Ferko, M, Kancirová, I, Jašová, M, Čarnická, S, Muráriková, M, Waczulíková, I, Sumbalová, Z, Kucharská, J, Uličná, O, Ravingerová, T, Ziegelhöffer, A

“…Remote ischemic preconditioning (RIP)-induced protection of myocardial energetics was well documented on the level of tissue, but data concerning the…”
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Stimulation of mitochondrial ATP synthase activity - a new diazoxide-mediated mechanism of cardioprotection by Jašová, M, Kancirová, I, Muráriková, M, Farkašová, V, Waczulíková, I, Ravingerová, T, Ziegelhöffer, A, Ferko, M

“…Pharmacological preconditioning by diazoxide and a model of experimental streptozotocin-induced acute diabetes mellitus (STZ-DM) provided similar levels of…”
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Remote preconditioning as a novel "conditioning" approach to repair the broken heart: potential mechanisms and clinical applications by Ravingerova, T, Farkasova, V, Griecsova, L, Carnicka, S, Murarikova, M, Barlaka, E, Kolar, F, Bartekova, M, Lonek, L, Slezak, J, Lazou, A

“…Remote ischemic preconditioning (RIPC) is a novel strategy of protection against ischemia-reperfusion (IR) injury in the heart (and/or other organs) by brief…”
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Impaired PI3K/Akt signaling as a potential cause of failure to precondition rat hearts under conditions of simulated hyperglycemia by Zálešák, M, Blažíček, P, Gablovský, I, Ledvényiová, V, Barteková, M, Ziegelhöffer, A, Ravingerová, T

“…The aim of the study was to evaluate the impact of simulated acute hyperglycemia (HG) on PI3K/Akt signaling in preconditioned and non-preconditioned isolated…”
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Upregulation of genes involved in cardiac metabolism enhances myocardial resistance to ischemia/reperfusion in the rat heart by Ravingerová, T, Carnická, S, Ledvényiová, V, Barlaka, E, Galatou, E, Chytilová, A, Mandíková, P, Nemčeková, M, Adameová, A, Kolář, F, Lazou, A

“…Genes encoding enzymes involved in fatty acids (FA) and glucose oxidation are transcriptionally regulated by peroxisome proliferator-activated receptors…”
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Participation of heart mitochondria in myocardial protection against ischemia/reperfusion injury: benefit effects of short-term adaptation processes by Ferko, M, Kancirová, I, Jašová, M, Waczulíková, I, Čarnická, S, Kucharská, J, Uličná, O, Vančová, O, Muráriková, M, Ravingerová, T, Ziegelhöffer, A

“…Acute streptozotocin diabetes mellitus (DM) as well as remote ischemic preconditioning (RPC) has shown a favorable effect on the postischemic-reperfusion…”
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Simvastatin alleviates myocardial contractile dysfunction and lethal ischemic injury in rat heart independent of cholesterol-lowering effects by Adameova, A, Harcarova, A, Matejikova, J, Pancza, D, Kuzelova, M, Carnicka, S, Svec, P, Bartekova, M, Styk, J, Ravingerova, T

“…Statins, the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, are most frequently used drugs in the prevention of coronary artery…”
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Involvement of membrane fluidity in endogenous protective processes running on subcellular membrane systems of the rat heart by Ziegelhöffer, A, Waczulíková, I, Ferko, M, Šikurová, L, Mujkošová, J, Ravingerová, T

“…Membrane fluidity is a widely recognized biophysical variable that provides information about structural organization of the subcellular membranes exhibiting…”
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Severity of lethal ischemia/reperfusion injury in rat hearts subjected to ischemic preconditioning is increased under conditions of simulated hyperglycemia by Zálešák, M, Blažíček, P, Pancza, D, Ledvényiová, V, Barteková, M, Nemčeková, M, Čarnická, S, Ziegelhöffer, A, Ravingerová, T

“…The aim of our study was to characterize resistance to ischemia/reperfusion (I/R) injury in Langendorff-perfused rat hearts and effectivity of ischemic…”
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Distinct effects of acute pretreatment with lipophilic and hydrophilic statins on myocardial stunning, arrhythmias and lethal injury in the rat heart subjected to ischemia/reperfusion by Čarnická, S, Adameová, A, Nemčeková, M, Matejíková, J, Pancza, D, Ravingerová, T

“…Although both lipophilic and more hydrophilic statins share the same pathway of the inhibition of HMG-CoA reductase, their pleiotropic cardioprotective effects…”
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Reduced susceptibility to ischemia-induced arrhythmias in the preconditioned rat heart is independent of PI3-kinase/Akt by Ravingerova, T, Matejikova, J, Pancza, D, Kolar, F

“…We examined the involvement of phosphatidylinositol 3-kinase (PI3K) and its effector protein kinase B (Akt) in cardioprotective effects of ischemic…”
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