Search Results - "RAVERT, Hayden T"

An improved synthesis of the radiolabeled prostate-specific membrane antigen inhibitor, [18F]DCFPyL by Ravert, Hayden T., Holt, Daniel P., Chen, Ying, Mease, Ronnie C., Fan, Hong, Pomper, Martin G., Dannals, Robert F.

“…The radiosynthesis of [18F]DCFPyL on 2 distinct automated platforms with full regulatory compliant quality control specifications is described. The radiotracer…”
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N-[N-[(S)-1,3-Dicarboxypropyl]Carbamoyl]-4-[18F]Fluorobenzyl-l-Cysteine, [18F]DCFBC: A New Imaging Probe for Prostate Cancer by Mease, Ronnie C, Dusich, Crystal L, Foss, Catherine A, Ravert, Hayden T, Dannals, Robert F, Seidel, Jurgen, Prideaux, Andrew, Fox, James J, Sgouros, George, Kozikowski, Alan P, Pomper, Martin G

“…Purpose: Previously, we showed successful imaging of xenografts that express the prostate-specific membrane antigen (PSMA) using small-animal positron emission…”
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Synthesis and quality control of [18F]T807 for tau PET imaging by Holt, Daniel P., Ravert, Hayden T., Dannals, Robert F.

“…The detailed synthesis and quality control of [18F]T807, radiotracer for tau protein aggregate imaging, are described. The radiotracer synthesis was…”
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Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen: In vivo Imaging in Experimental Models of Prostate Cancer by FOSS, Catherine A, MEASE, Ronnie C, HONG FAN, YUCHUAN WANG, RAVEN, Hayden T, DANNALS, Robert F, OLSZEWSKI, Rafal T, HESTON, Warren D, KOZIKOWSKI, Alan P, POMPER, Martin G

“…Purpose: Prostate-specific membrane antigen (PSMA) is a cell surface protein that is overexpressed in prostate cancer, including hormone-refractory and…”
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Synthesis and in vivo evaluation of ( S)-6-(4-fluorophenoxy)-3-((1-[ 11C]methylpiperidin-3-yl)methyl)-2- o-tolylquinazolin-4(3 H)-one, a potential PET tracer for growth hormone secretagogue receptor (GHSR) by Potter, Rachel, Horti, Andrew G., Ravert, Hayden T., Holt, Daniel P., Finley, Paige, Scheffel, Ursula, Dannals, Robert F., Wahl, Richard L.

“…We report the synthesis, in vitro, and in vivo evaluation of 6-(4-fluorophenoxy)-3-((1-[ 11C]methylpiperidin-3-yl)methyl)-2- o-tolylquinazolin-4(3 H)-one ([…”
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Radiochemical synthesis and in vivo evaluation of [18F]AZ11637326: An agonist probe for the α7 nicotinic acetylcholine receptor by Ravert, Hayden T., Dorff, Peter, Foss, Catherine A., Mease, Ronnie C., Fan, Hong, Holmquist, Christopher R., Phillips, Eifion, McCarthy, Dennis J., Heys, J. Richard, Holt, Daniel P., Wang, Yuchuan, Endres, Christopher J., Dannals, Robert F., Pomper, Martin G.

“…The alpha-7 nicotinic acetylcholine receptor (α7 nAChR) is key in brain communication and has been implicated in the pathophysiology of diseases of the central…”
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Quantitative Multi-modal Brain Autoradiography of Glutamatergic, Dopaminergic, Cannabinoid, and Nicotinic Receptors in Mutant Disrupted-In-Schizophrenia-1 (DISC1) Mice by Kim, Jongho, Horti, Andrew G., Mathews, William B., Pogorelov, Vladimir, Valentine, Heather, Brasic, James R., Holt, Daniel P., Ravert, Hayden T., Dannals, Robert F., Zhou, Luewi, Jedynak, Bruno, Kamiya, Atsushi, Pletnikov, Mikhail V., Wong, Dean F.

“…Purpose Disrupted-in-schizophrenia-1 (DISC1) is a promising genetic susceptibility factor for major psychiatric conditions, such as schizophrenia. We…”
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Column-switching HPLC for the analysis of plasma in PET imaging studies by Hilton, John, Yokoi, Fuji, Dannals, Robert F, Ravert, Hayden T, Szabo, Zsolt, Wong, Dean F

“…A column-switch high performance liquid chromatography method for the analysis of 4 mL of plasma is described with six examples of chromatography of […”
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Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer’s Disease with Positron Emission Tomography by Gobbi, Luca C, Knust, Henner, Körner, Matthias, Honer, Michael, Czech, Christian, Belli, Sara, Muri, Dieter, Edelmann, Martin R, Hartung, Thomas, Erbsmehl, Isabella, Grall-Ulsemer, Sandra, Koblet, Andreas, Rueher, Marianne, Steiner, Sandra, Ravert, Hayden T, Mathews, William B, Holt, Daniel P, Kuwabara, Hiroto, Valentine, Heather, Dannals, Robert F, Wong, Dean F, Borroni, Edilio

“…Aggregates of tau and beta amyloid (Aβ) plaques constitute the histopathological hallmarks of Alzheimer’s disease and are prominent targets for novel…”
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Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR by Wong, Dean F., Kuwabara, Hiroto, Horti, Andrew G., Raymont, Vanessa, Brasic, James, Guevara, Maria, Ye, Weiguo, Dannals, Robert F., Ravert, Hayden T., Nandi, Ayon, Rahmim, Arman, Ming, Jeffrey E., Grachev, Igor, Roy, Christine, Cascella, Nicola

“…Several studies have examined the link between the cannabinoid CB1 receptor and several neuropsychiatric illnesses, including schizophrenia. As such, there is…”
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The dopamine transporter is decreased in the striatum of subjects with restless legs syndrome by Earley, Christopher J, Kuwabara, Hiroto, Wong, Dean F, Gamaldo, Charlene, Salas, Rachel, Brasic, James, Ravert, Hayden T, Dannals, Robert F, Allen, Richard P

“…Prior studies, all using SPECT techniques, failed to find any differences for dopamine transporter (DAT) in restless legs syndrome (RLS) subjects. The distinct…”
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In vivo measurement of cell proliferation in canine brain tumor using C-11-labeled FMAU and PET by Conti, Peter S, Bading, James R, Mouton, Peter P, Links, Jonathan M, Alauddin, Mian M, Fissekis, John D, Ravert, Hayden T, Hilton, John, Wong, Dean F, Anderson, James H

“…Abstract Introduction Noncatabolized thymidine analogs are being developed for use in imaging DNA synthesis. We sought to relate a labeling index measured by…”
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Increased synaptic dopamine in the putamen in restless legs syndrome by Earley, Christopher J, Kuwabara, Hiroto, Wong, Dean F, Gamaldo, Charlene, Salas, Rachel E, Brašić, James R, Ravert, Hayden T, Dannals, Robert F, Allen, Richard P

“…Prior studies using positron emission tomography (PET) or single-photon emission computed tomography techniques have reported inconsistent findings regarding…”
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Radiosynthesis of 3-[18F]fluoropropyl and 4-[18F]fluorobenzyl triarylphosphonium ions by Ravert, Hayden T., Madar, Igal, Dannals, Robert F.

“…3‐[18F]Fluoropropyl‐, 4‐[18F]fluorobenzyl‐triphenylphosphonium and 4‐[18F]fluorobenzyltris‐4‐dimethylaminophenylphosphonium cations were synthesized in…”
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Positron emission tomographic studies of brain dopamine and serotonin transporters in abstinent (±)3,4-methylenedioxymethamphetamine (“ecstasy”) users: relationship to cognitive performance by McCann, Una D., Szabo, Zsolt, Vranesic, Melin, Palermo, Michael, Mathews, William B., Ravert, Hayden T., Dannals, Robert F., Ricaurte, George A.

“…Background (±)3,4-Methylenedioxymethamphetamine (MDMA, “ecstasy”) is a recreational drug and brain serotonin (5-HT) neurotoxin. Under certain conditions, MDMA…”
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Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2) by Horti, Andrew G., Gao, Yongjun, Ravert, Hayden T., Finley, Paige, Valentine, Heather, Wong, Dean F., Endres, Christopher J., Savonenko, Alena V., Dannals, Robert F.

“…[11C]A-836339, a new potential PET radioligand for imaging of cannabinoid subtype 2 receptors (CB2), demonstrated high CB2 specific binding in the mouse models…”
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Quantitative PET Studies of the Serotonin Transporter in MDMA Users and Controls Using [ C]McN5652 and [ C]DASB by MCCANN, Una D, SZABO, Zsolt, SECKIN, Esen, ROSENBLATT, Peter, MATHEWS, William B, RAVERT, Hayden T, DANNALS, Robert F, RICAURTE, George A

“…(+/-)3,4-Methylenedioxymethamphetamine (MDMA, 'Ecstasy') is a widely used illicit drug that produces toxic effects on brain serotonin axons and axon terminals…”
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An optimized radiosynthesis of [18F]FNDP, a positron emission tomography radiotracer for imaging soluble epoxide hydrolase (sEH) by Azad, Babak Behnam, Holt, Daniel P., Ravert, Hayden T., Horti, Andrew G., Dannals, Robert F.

“…In this concise practitioner protocol, the radiochemical synthesis of [18F]FNDP suitable for human positron emission tomography studies is described and the…”
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Synthesis of a mGluR5 antagonist using [11C]copper(I) cyanide by Mathews, William B., Monn, James A., Ravert, Hayden T., Holt, Daniel P., Schoepp, Darryle D., Dannals, Robert F.

“…5‐(2‐Phenylethynyl)pyridine‐3‐[11C]carbonitrile ([11C]LY2232645), a metabotropic glutamate 5 receptor (mGluR5) antagonist, was synthesized by a…”
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A microwave radiosynthesis of the 4-[18F]-fluorobenzyltriphenylphosphonium ion by Ravert, Hayden T., Holt, Daniel P., Dannals, Robert F.

“…The 4‐[18F]‐fluorobenzyltriphenylphosphonium cation was synthesized by a series of microwave reactions from no carrier added [18F]‐fluoride. The microwave…”
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