Search Results - "RAVASI, Laura"

Targeting chelatable iron as a therapeutic modality in Parkinson's disease by Devos, David, Moreau, Caroline, Devedjian, Jean Christophe, Kluza, Jérome, Petrault, Maud, Laloux, Charlotte, Jonneaux, Aurélie, Ryckewaert, Gilles, Garçon, Guillaume, Rouaix, Nathalie, Duhamel, Alain, Jissendi, Patrice, Dujardin, Kathy, Auger, Florent, Ravasi, Laura, Hopes, Lucie, Grolez, Guillaume, Firdaus, Wance, Sablonnière, Bernard, Strubi-Vuillaume, Isabelle, Zahr, Noel, Destée, Alain, Corvol, Jean-Christophe, Pöltl, Dominik, Leist, Marcel, Rose, Christian, Defebvre, Luc, Marchetti, Philippe, Cabantchik, Z Ioav, Bordet, Régis

“…The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a chelation strategy aimed at reducing oxidative damage associated with…”
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Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors by Khamari, Raeeka, Trinh, Anne, Gabert, Pierre Elliott, Corazao-Rozas, Paola, Riveros-Cruz, Samuel, Balayssac, Stephane, Malet-Martino, Myriam, Dekiouk, Salim, Joncquel Chevalier Curt, Marie, Maboudou, Patrice, Garçon, Guillaume, Ravasi, Laura, Guerreschi, Pierre, Mortier, Laurent, Quesnel, Bruno, Marchetti, Philippe, Kluza, Jerome

“…Targeted therapies as BRAF and MEK inhibitor combination have been approved as first-line treatment for BRAF-mutant melanoma. However, disease progression…”
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My belief or yours? Differential theory of mind deficits in frontotemporal dementia and Alzheimer's disease by LE BOUC, Raphaël, LENFANT, Pierre, DELBEUCK, Xavier, RAVASI, Laura, LEBERT, Florence, SEMAH, Franck, PASQUIER, Florence

“…Theory of mind reasoning-the ability to understand someone else's mental states, such as beliefs, intentions and desires-is crucial in social interaction. It…”
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Multifunctional ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI by Bechet, Denise, PhD, Auger, Florent, PhD, Couleaud, Pierre, PhD, Marty, Eric, Ravasi, Laura, MD, Durieux, Nicolas, Bonnet, Corinne, Plénat, François, MD, Frochot, Céline, Mordon, Serge, Tillement, Olivier, Vanderesse, Régis, Lux, François, Perriat, Pascal, Guillemin, François, MD, Barberi-Heyob, Muriel

“…Abstract Photodynamic therapy (PDT) for brain tumors appears to be complementary to conventional treatments. A number of studies show the major role of the…”
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Translational Challenge Models in Support of Efficacy Studies: Effect of Cerebral Hypoxia on Cognitive Performances in Rodents by Deguil, Julie, Ravasi, Laura, Lanteaume, Laura, Lamberty, Yves, Bordet, Regis

“…Empirical evidence currently supports the idea that neurovascular dysfunction is involved in the neurodegenerative process of Alzheimer's disease (AD). In…”
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Early Development of Symptomatic Drugs in AD: A Systematic Review of the Use of Biomarkers by Deguil, Julie, Ravasi, Laura, Lamberty, Yves, Auffret, Alexandra, Payoux, Pierre, Leroy, Christopher, Derambure, Philippe, Bordet, Régis

“…Pharmacological therapies currently marketed for Alzheimer's disease (AD) are only symptomatic and show limited effects in terms of clinical benefit. Thus, the…”
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Maternal stress programs accelerated aging of the basal ganglia motor system in offspring by Marrocco, Jordan, Verhaeghe, Remy, Bucci, Domenico, Di Menna, Luisa, Traficante, Anna, Bouwalerh, Hammou, Van Camp, Gilles, Ghiglieri, Veronica, Picconi, Barbara, Calabresi, Paolo, Ravasi, Laura, Cisani, Francesca, Bagheri, Farzaneh, Pittaluga, Anna, Bruno, Valeria, Battaglia, Giuseppe, Morley-Fletcher, Sara, Nicoletti, Ferdinando, Maccari, Stefania

“…Early-life stress involved in the programming of stress-related illnesses can have a toxic influence on the functioning of the nigrostriatal motor system…”
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[123 I]-FP-CIT and [99m Tc]-HMPAO single photon emission computed tomography in a new sporadic case of rapid-onset dystonia–parkinsonism by Zanotti-Fregonara, Paolo, Vidailhet, Marie, Kas, Aurélie, Ozelius, Laurie J, Clot, Fabienne, Hindié, Elif, Ravasi, Laura, Devaux, Jean-Yves, Roze, Emmanuel

“…Abstract Rapid-onset dystonia-parkinsonism (RDP) is a rare, autosomal-dominantly inherited syndrome characterized by abrupt onset, over hours to days, of…”
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Intraoperative Avidination for Radionuclide Therapy: A Prospective New Development to Accelerate Radiotherapy in Breast Cancer by PAGANELLI, Giovanni, FERRARI, Mahila, FIORENZA, Maurizio, CHINOL, Marco, PAPI, Stefano, ZANNA, Claudio, CARMINATI, Paolo, VERONESI, Umberto, RAVASI, Laura, CREMONESI, Marta, DE CICCO, Concetta, GALIMBERTI, Viviana, SIVOLAPENKO, Gregory, LUINI, Alberto, DE SANTIS, Rita, LAVINIA TRAVAINI, Laura

“…Purpose: In a continuous effort to seek for anticancer treatments with minimal side effects, we aim at proving the feasibility of the Intraoperative…”
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Circulating levels of VCAM and MMP-2 may help identify patients with more aggressive prostate cancer by De Cicco, Concetta, Ravasi, Laura, Zorzino, Laura, Sandri, Maria Teresa, Botteri, Edoardo, Verweij, Fabrizio, Granchi, Donatella, de Cobelli, Ottavio, Paganelli, Giovanni

“…Prostate adenocarcinoma is generally characterized by slow progression although some phenotypes have a more aggressive behavior with tendency to local invasion…”
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[18 F]FDG positron emission tomography/computed tomography and multidetector computed tomography roles in thymic lesion treatment planning by Travaini, Laura L, Petralia, Giuseppe, Trifirò, Giuseppe, Ravasi, Laura, Galetta, Domenico, Carbone, Giuseppe, Falcini, Fabio, Spaggiari, Lorenzo, Bellomi, Massimo, Paganelli, Giovanni

“…Summary Rationale Thymic masses may represent an unsolved diagnostic problem which often require surgical procedures for an accurate staging. A non-invasive…”
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Fluoro-, bromo-, and iodopaclitaxel derivatives: synthesis and biological evaluation by Kiesewetter, Dale O, Jagoda, Elaine M, Kao, Chih-Hao K, Ma, Ying, Ravasi, Laura, Shimoji, Kazuaki, Szajek, Lawrence P, Eckelman, William C

“…Paclitaxel (Taxol®) is a clinically important chemotherapeutic agent. We describe the synthesis of fluoro-, bromo-, and iodopaclitaxel and their [ 18F]fluoro-,…”
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Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with Lu-177-Dotatate: an analysis of the NETTER-1 study by Strosberg, Jonathan, Kunz, Pamela L., Hendifar, Andrew, Yao, James, Bushnell, David, Kulke, Matthew H., Baum, Richard P., Caplin, Martyn, Ruszniewski, Philippe, Delpassand, Ebrahim, Hobday, Timothy, Verslype, Chris, Benson, Al, Srirajaskanthan, Rajaventhan, Pavel, Marianne, Mora, Jaume, Berlin, Jordan, Grande, Enrique, Reed, Nicholas, Seregni, Ettore, Paganelli, Giovanni, Severi, Stefano, Morse, Michael, Metz, David C., Ansquer, Catherine, Courbon, Frederic, Al-Nahhas, Adil, Baudin, Eric, Giammarile, Francesco, Taieb, David, Mittra, Erik, Wolin, Edward, O'Dorisio, Thomas M., Lebtahi, Rachida, Deroose, Christophe M., Grana, Chiara M., Bodei, Lisa, Öberg, Kjell, Polack, Berna Degirmenci, He, Beilei, Mariani, Maurizio F., Gericke, Germo, Santoro, Paola, Erion, Jack L., Ravasi, Laura, Krenning, Eric

“…Purpose To assess the impact of baseline liver tumour burden, alkaline phosphatase (ALP) elevation, and target lesion size on treatment outcomes with…”
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Neuroinflammation and Aβ Accumulation Linked To Systemic Inflammation Are Decreased By Genetic PKR Down-Regulation by Carret-Rebillat, Anne-Sophie, Pace, Clarisse, Gourmaud, Sarah, Ravasi, Laura, Montagne-Stora, Samantha, Longueville, Sophie, Tible, Marion, Sudol, Erika, Chang, Raymond Chuen-Chung, Paquet, Claire, Mouton-Liger, François, Hugon, Jacques

“…Alzheimer's disease (AD) is a neurodegenerative disorder, marked by senile plaques composed of amyloid-β (Aβ) peptide, neurofibrillary tangles, neuronal loss…”
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Role of cortical microbleeds in cognitive impairment: In vivo behavioral and imaging characterization of a novel murine model by Bergeron, Sandrine, Chen, Yaohua, Auger, Florent, Deguil, Julie, Durieux, Nicolas, Skrobala, Emilie, Barus, Romain, Potey, Camille, Cordonnier, Charlotte, Pasquier, Florence, Ravasi, Laura, Bordet, Régis, Gautier, Sophie

“…Cerebral microbleeds (CMBs) could contribute to cognitive impairment in the general population and in patients with dementia. We designed a study to (i)…”
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Evaluation of [ 76Br]FBAU 3′,5′-dibenzoate as a lipophilic prodrug for brain imaging by Kao, Chih-Hao K, Waki, Atsuo, Sassaman, Mark B, Jagoda, Elaine M, Szajek, Lawrence P, Ravasi, Laura, Shimoji, Kazuaki, Eckelman, William C

“…[ 76Br]FBAU is a potential PET tracer for assessing proliferation. This study proposes that [ 76Br]FBAU 3′,5′-dibenzoate has higher blood-brain-barrier…”
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Detection of Apoptosis with ^sup 99m^Tc rh Annexin-V 128 Imaging in Asymptomatic Patients with Carotid Atherosclerotic Plaque by Massalha, Samia, Ferro, Paola, Ascah, Kathryn, Carey, Clare, Marvin, Brian, Dwivedi, Girish, Wells, R Glenn, Ravasi, Laura, Ruddy, Terrence

“…Background: Apoptosis plays an important role in the late progression of atherosclerosclerotic plaque and may be useful for identifying advanced and…”
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Detection of Apoptosis with 99mTc rh Annexin-V 128 Imaging in Asymptomatic Patients with Carotid Atherosclerotic Plaque by Massalha, Samia, Ferro, Paola, Ascah, Kathryn, Carey, Clare, Marvin, Brian, Dwivedi, Girish, Wells, R Glenn, Ravasi, Laura, Ruddy, Terrence

“…Background: Apoptosis plays an important role in the late progression of atherosclerosclerotic plaque and may be useful for identifying advanced and…”
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Clinical outcomes in patients with baseline renal dysfunction in the NETTER-1 study: 177Lu-Dotatate vs. high dose octreotide in progressive midgut neuroendocrine tumors by Strosberg, Jonathan R., Wolin, Edward M., Chasen, Beth A., Kulke, Matthew H., Bushnell, David L, Caplin, Martyn E., Baum, Richard P., Hobday, Timothy J., Hendifar, Andrew Eugene, Ravasi, Laura, Oberg, Kjell E., Ruszniewski, Philippe B., Krenning, Eric

“…Abstract only…”
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Analysis of patient diaries in the NETTER-1 Study of 177Lu-DOTATATE versus high-dose octreotide in progressive midgut neuroendocrine tumors by Strosberg, Jonathan R., Wolin, Edward M., Chasen, Beth A., Kulke, Matthew H., Bushnell, David L, Caplin, Martyn, Baum, Richard P., Hobday, Timothy J., Hendifar, Andrew Eugene, Santoro, Paola, Broberg, Per, Demange, Arnaud, Oberg, Kjell E., Ruszniewski, Philippe B., Ravasi, Laura, Krenning, Eric

“…Abstract only 4111 Background: The primary statistical analysis for the NETTER-1 trial showed a clinically and statistically significant PFS benefit with 177…”
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