Search Results - "RAUL, Francis"

Polyamines and apoptosis by Seiler, Nikolaus, Raul, Francis

“…The natural polyamines putrescine, spermidine and spermine are in multiple ways involved in cell growth and the maintenance of cell viability. In the course of…”
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Polyamines and the Intestinal Tract by Seiler, Nikolaus, Raul, Francis

“…Owing to their high turnover, the intestinal mucosal cells have a particularly high requirement for polyamines. Therefore, they are an excellent charcol for…”
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Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis by Gossé, Francine, Guyot, Sylvain, Roussi, Stamatiki, Lobstein, Annelise, Fischer, Barbara, Seiler, Nikolaus, Raul, Francis

“…Apples contain several classes of polyphenols: monomers (catechins, epicatechins) and oligomers/polymers, such as the procyanidins. Our aim was (i) to study…”
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The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells by Kauntz, Henriette, Bousserouel, Souad, Gossé, Francine, Raul, Francis

“…Silibinin, a flavonolignan, is the major active component of the milk thistle plant ( Silybum marianum ) and has been shown to possess anti-neoplastic…”
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Carcinogenic properties of proteins with pro-inflammatory activity from Streptococcus infantarius (formerly S.bovis) by Biarc, Jordane, Nguyen, Isabelle S., Pini, Annelise, Gossé, Francine, Richert, Sophie, Thiersé, Danielle, Van Dorsselaer, Alain, Leize-Wagner, Emmanuelle, Raul, Francis, Klein, Jean-Paul, Schöller-Guinard, Marie

“…Several studies reported linkage between bacterial infections and carcinogenesis. Streptococcus bovis was traditionally considered as a lower grade pathogen…”
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Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells by Schneider, Yann, Vincent, Florence, Duranton, Benoı̂t, Badolo, Lassina, Gossé, Francine, Bergmann, Christian, Seiler, Nikolaus, Raul, Francis

“…Resveratrol, a natural polyphenolic phytoalexine present in grapes and wines, has been reported to exert a variety of important pharmacological effects. We…”
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Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts by Carnesecchi, Stephanie, Bras-Gonçalves, Rui, Bradaia, Amyaouch, Zeisel, Mirjam, Gossé, Francine, Poupon, Marie-France, Raul, Francis

“…We investigated on colon cancer cells the effect of geraniol on thymidylate synthase and thymidine kinase expression, two enzymes related to 5-fluorouracil…”
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Apple procyanidins activate apoptotic signaling pathway in human colon adenocarcinoma cells by a lipid-raft independent mechanism by Maldonado-Celis, Maria E., Bousserouel, Souad, Gossé, Francine, Lobstein, Annelise, Raul, Francis

“…Flavonoids are polyphenolic compounds able to favour cholesterol-lipid-raft formation and control cell signaling pathways by targeting receptors at the cell…”
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Early modulation of gene expression used as a biomarker for chemoprevention in a preclinical model of colon carcinogenesis by Bousserouel, Souad, Lamy, Virginie, Gossé, Francine, Lobstein, Annelise, Marescaux, Jacques, Raul, Francis

“…By using the rat azoxymethane (AOM)‐induced colon carcinogenesis model, which mirrors many clinical features of human colorectal cancer, we examined whether…”
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Synthesis of highly pure oxyphytosterols and (oxy)phytosterol esters Part II. (Oxy)-sitosterol esters derived from oleic acid and from 9,10-dihydroxystearic acid [1] by JULIEN-DAVID, Diane, GEOFFROY, Philippe, MARCHIONI, Eric, RAUL, Francis, AOUDE-WERNER, Dalal, MIESCH, Michel

“…Several efficient synthetic routes giving readily access to (oxy)-sitosterol esters and (oxy)-cholesterol esters derived respectively from oleic acid and from…”
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Flavanols and procyanidins of cocoa and chocolate inhibit growth and polyamine biosynthesis of human colonic cancer cells by Carnésecchi, Stéphanie, Schneider, Yann, Lazarus, Sheryl A, Coehlo, David, Gossé, Francine, Raul, Francis

“…The effects of cocoa powder and extracts with different amounts of flavanols and related procyanidin oligomers were investigated on the growth of Caco-2 cells…”
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Potentiation of apple procyanidin-triggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells by GOSSE, Francine, ROUSSI, Stamatiki, GUYOT, Sylvain, SCHOENFELDER, Angèle, MANN, André, BERGERAT, Jean-Pierre, SEILER, Nikolaus, RAUL, Francis

“…Apple procyanidins have chemopreventive properties in a model of colon cancer, they affect intracellular signalling pathways, and trigger apoptosis in a human…”
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Effects of agmatine accumulation in human colon carcinoma cells on polyamine metabolism, DNA synthesis and the cell cycle by Mayeur, Camille, Veuillet, Géraldine, Michaud, Marie, Raul, Francis, Blottière, Hervé M., Blachier, François

“…Putrescine, spermidine and spermine are low molecular polycations that play important roles in cell growth and cell cycle progression of normal and malignant…”
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Antiangiogenic Properties of Lupulone, a Bitter Acid of Hop Cones by SIEGEL, Luz, MITERNIQUE-GROSSE, Anne, GRIFFON, Christian, KLEIN-SOYER, Claudine, LOBSTEIN, Annelise, RAUL, Francis, STEPHAN, Dominique

“…Background: Angiogenesis is the result of intricate steps regulated by the balance between agonistic and antagonistic effectors. Disturbance of this balance…”
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Chemopreventive effects of lupulone, a hop {beta}-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis by Lamy, Virginie, Roussi, Stamatiki, Chaabi, Mehdi, Gossé, Francine, Schall, Nicolas, Lobstein, Annelise, Raul, Francis

“…The bitter acids of hops (Humulus lupulus L.) mainly consist of humulones or alpha-acids and lupulones or beta-acids. We aimed to evaluate the…”
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Synergism between Apple Procyanidins and Lysosomotropic Drugs: Potential in Chemoprevention by SEILER, Nikolaus, CHAABI, Mehdi, ROUSSI, Stamatiki, GOSSE, Francine, LOBSTEIN, Annelise, RAUL, Francis

“…Background: Procyanidins are apple constituents with potential in colon cancer chemoprevention. Materials and Methods: Human colon cancer derived metastatic…”
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The polyamine oxidase inactivator MDL 72527 by Seiler, Nikolaus, Duranton, Benoit, Raul, Francis

“…Polyamine oxidase is a FAD-dependent amine oxidase, which is constitutively expressed in nearly all tissues of the vertebrate organism. In 1985,…”
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PRO-APOPTOTIC EFFECTS OF APPLE PROCYANIDINS IN HUMAN COLON CANCER CELLS AND THEIR DERIVED METASTATIC CELLS by MALDONADO C., María E., RAUL, Francis

“…Apples are a rich source of Procyanidins (Pcy) which are able to inhibit colon carcinogenesis in animal models, but the mechanisms through which this occurs…”
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Aging: a barrier to renutrition? nutritional and immunologic evidence in rats by WALRAND, Stéphane, CHAMBON-SAVANOVITCH, Chantal, FELGINES, Catherine, CHASSAGNE, Jacques, RAUL, Francis, NORMAND, Bernadette, FARGES, Marie-Chantal, BEAUFRERE, Bernard, VASSON, Marie-Paule, CYNOBER, Luc

“…Previous reports suggest that correcting the malnourished state is more difficult in elderly people than in younger ones and that protein requirements may be…”
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Implicación de NF-κB y p53 en la expresión de receptores de muerte-TRAIL y apoptosis por procianidinas en células metastásicas humanas SW620 by Maldonado, María Elena, Bousserouel, Souad, Gossé, Francine, Lobstein, Annelise, Raul, Francis

“…Introducción. Se ha demostrado que el factor nuclear-κB y p53 aumentan los mediadores proapoptósicos como los receptores de muerte TRAIL-DR4/-DR5, según el…”
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