Search Results - "RATSCHILLER, D"

High levels of circulating CD34+ cells at autologous stem cell collection are associated with favourable prognosis in multiple myeloma by Raschle, J, Ratschiller, D, Mans, S, Mueller, B U, Pabst, T

“…Background: High-dose chemotherapy with autologous stem cell transplantation is a cornerstone in the first-line treatment of multiple myeloma patients…”
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Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability by SMITH, S. L, BOWERS, N. L, BETTICHER, D. C, GAUTSCHI, O, RATSCHILLER, D, HOBAN, P. R, BOOTON, R, SANTIBANEZ-KOREF, M. F, HEIGHWAY, J

“…Aurora kinases are key regulators of chromosome segregation during mitosis. We have previously shown by microarray analysis of primary lung carcinomas and…”
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Cyclin D1 Overexpression in Bronchial Epithelia of Patients With Lung Cancer Is Associated With Smoking and Predicts Survival by Ratschiller, D, Heighway, J, Gugger, M, Kappeler, A, Pirnia, F, Schmid, R A, Borner, M M, Betticher, D C

“…Cyclin D1 is overexpressed in almost 60% of resectable non-small-cell lung cancer (NSCLC). In the absence of cyclin D1 gene amplification, overexpression is…”
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Origin and prognostic value of circulating KRAS mutations in lung cancer patients by Gautschi, O, Huegli, B, Ziegler, A, Gugger, M, Heighway, J, Ratschiller, D, Mack, P.C, Gumerlock, P.H, Kung, H.J, Stahel, R.A, Gandara, D.R, Betticher, D.C

“…Abstract Because of the current controversy on the origin and clinical value of circulating KRAS codon 12 mutations in lung cancer, we screened 180 patients…”
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S100A2 is strongly expressed in airway basal cells, preneoplastic bronchial lesions and primary non-small cell lung carcinomas by SMITH, S. L, GUGGER, M, HOBAN, P, RATSCHILLER, D, WATSON, S. G, FIELD, J. K, BETTICHER, D. C, HEIGHWAY, J

“…S100A2 gene products were shown to be frequently and dramatically over-represented in non-small cell lung cancer (NSCLC) lesions over normal tissue by…”
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Cladribine (2‐CDA) given as subcutaneous bolus injections is active in pretreated Waldenström's macroglobulinaemia by Betticher, D. C., Hsu Schmitz, S.‐F., Ratschiller, D., Von Rohr, A., Egger, T., Pugin, P., Stalder, M., Hess, U., Fey, M. F., Cerny, T.

“…Clinical trials with intravenous cladribine infusions in pretreated patients with Waldenström's macroglobulinaemia have shown a response rate of 40%. Our…”
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Fewer infections, but maintained antitumor activity with lower-dose versus standard-dose cladribine in pretreated low-grade non-Hodgkin's lymphoma by Betticher, D C, von Rohr, A, Ratschiller, D, Schmitz, S F, Egger, T, Sonderegger, T, Herrmann, R, Kroner, T, Zulian, G B, Cavalli, F, Fey, M F, Cerny, T

“…To study the efficacy and the safety of cladribine (2-chlorodeoxyadenosine [2-CDA]) administered at two different dosages. In this two-cohort study, patients…”
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Reduced dose of subcutaneous cladribine induces identical response rates but decreased toxicity in pretreated chronic lymphocytic leukaemia by Betticher, D. C., Ratschiller, D., Schmitz, S.-F. Hsu, von Rohr, A., Hess, U., Zulian, G., Wernli, M., Tichelli, A., Tobler, A., Fey, M. F., Cerny, T.

“…Purpose To study the efficacy and the safety of cladribine (2-chlorodeoxyadenosine, 2-CDA) administered as 24-hour infusions or as subcutaneous bolus…”
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Risk Assessment in Patients with Acute Myeloid Leukemia and a Normal Karyotype by BIENZ, Marianne, LUDWIG, Madleina, MUELLER, Beatrice U, OPPLIGER LEIBUNDGUT, Elisabeth, RATSCHILLER, Daniel, SOLENTHALER, Max, FEY, Martin F, PABST, Thomas

“…Purpose: The recognition of a number of leukemia-specific cytogenetic abnormalities and their role as independent prognostic factors have provided considerable…”
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Circulating Deoxyribonucleic Acid As Prognostic Marker in Non–Small-Cell Lung Cancer Patients Undergoing Chemotherapy by GAUTSCHI, Oliver, BIGOSCH, Colette, STAHEL, Rolf A, ZIEGLER, Annemarie, HUEGLI, Barbara, JERMANN, Monika, MARX, Arthur, CHASSE, Eveline, RATSCHILLER, Daniel, WEDER, Walter, JOERGER, Markus, BETTICHER, Daniel C

“…Circulating cell-free DNA is present in increased amounts in the blood of cancer patients, but the clinical relevance of this phenomenon remains unclear. We…”
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Expression profiling of primary non-small cell lung cancer for target identification by HEIGHWAY, Jim, KNAPP, Teresa, RICKERT, Paula, BOYCE, Lenetta, BRENNAND, Shelley, FIELD, John K, BETTICHER, Daniel C, RATSCHILLER, Daniel, GUGGER, Mathias, DONOVAN, Michael, LASEK, Amy

“…Using a panel of cDNA microarrays comprising 47 650 transcript elements, we have carried out a dual-channel analysis of gene expression in 39 resected primary…”
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Maspin - the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer - is strongly expressed in preneoplastic bronchial lesions by SMITH, Shirley L, WATSON, Suzanne G, RATSCHILLER, Daniel, GUGGER, Mathias, BETTICHER, Daniel C, HEIGHWAY, Jim

“…Maspin, SCCA1/2 and hurpin were identified by cDNA microarray analyses as dramatically differentially expressed transcripts in primary non-small cell lung…”
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Cyclin D1 ( CCND1) A870G gene polymorphism modulates smoking-induced lung cancer risk and response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC) patients by Gautschi, Oliver, Hugli, Barbara, Ziegler, Annemarie, Bigosch, Colette, Bowers, Naomi L., Ratschiller, Daniel, Jermann, Monika, Stahel, Rolf A., Heighway, Jim, Betticher, Daniel C.

“…The cyclin D1 ( CCND1) A870G gene polymorphism is linked to the outcome in patients with resectable non-small cell lung cancer (NSCLC). Here, we investigated…”
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Giant cell arteritis as unusual cause of critical arm ischemia by Ratschiller, Thomas, MD, Müller, Hannes, MD, Pirklbauer, Markus, MD, PhD, Silye, Rene, MD, Sulzbacher, Gregor, Zierer, Andreas, MD

“…Abstract Giant cell arteritis is an inflammatory vasculopathy of unknown etiology that typically affects the carotid artery and its branches. Symptomatic…”
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P-484 CCND1/Cyclin D1 A870G gene polymorphism is associated with non-small cell lung cancer (NSCLC) risk, and affects prognosis and response to chemotherapy by Gautschi, O., Huegli, B., Ziegler, A., Bigosch, C., Ratschiller, D., Bowers, N., Stahel, R., Heighway, J., Betticher, D.

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A high-resolution allelotype of B-cell chronic lymphocytic leukemia (B-CLL) by Novak, Urban, Oppliger Leibundgut, Elisabeth, Hager, Jörg, Mühlematter, Dominique, Jotterand, Martine, Besse, Celine, Leupin, Nicolas, Ratschiller, Daniel, Papp, Jeanette, Kearsey, Gina, Aebi, Stefan, Graber, Hans, Jaggi, Rolf, Lüthi, Jean-Marc, Meyer-Monard, Sandrine, Lathrop, Mark, Tobler, Andreas, Fey, Martin F.

“…The most frequent chromosomal aberrations in B-cell chronic lymphocytic leukemia (B-CLL) are deletions on 13q, 11q, and 17p, and trisomy 12, all of which are…”
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Cyclin dl overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival by RATSCHILLER, D, HEIGHWAY, J, GUGGER, M, KAPPELER, A, PIRNIA, F, SCHMID, R. A, BORNER, M. M, BETTICHER, D. C

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Reduced dose of subcutaneous cladribine induces identical response rates but decreased toxicity in pretreated chronic lymphocytic leukaemia. Swiss Group for Clinical Cancer Research (SAKK) by Betticher, D C, Ratschiller, D, Hsu Schmitz, S F, von Rohr, A, Hess, U, Zulian, G, Wernli, M, Tichelli, A, Tobler, A, Fey, M F, Cerny, T

“…To study the efficacy and the safety of cladribine (2-chlorodeoxyadenosine, 2-CDA) administered as 24-hour infusions or as subcutaneous bolus injections at two…”
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Cladribine (2-CDA) given as subcutaneous bolus injections is active in pretreated Waldenström's macroglobulinaemia. Swiss Group for Clinical Cancer Research (SAKK) by Betticher, D C, Hsu Schmitz, S F, Ratschiller, D, von Rohr, A, Egger, T, Pugin, P, Stalder, M, Hess, U, Fey, M F, Cerny, T

“…Clinical trials with intravenous cladribine infusions in pretreated patients with Waldenström's macroglobulinaemia have shown a response rate of 40%. Our…”
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Early Experiences With a New Three-Dimensional Annuloplasty Ring for the Treatment of Functional Tricuspid Regurgitation by Ratschiller, Thomas, MD, Guenther, Thomas, MD, Guenzinger, Ralf, MD, Noebauer, Christian, MD, Kehl, Victoria, Dr. rer. nat, Gertler, Ralph, MD, Lange, Ruediger, MD

“…Background Various techniques and devices have been proposed for tricuspid valve (TV) repair in patients with tricuspid regurgitation (TR). However, residual…”
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