Search Results - "RATHJEN, D. A"

Tumor Necrosis Factor (TNF) and a TNF-Mimetic Peptide Modulate the Granulomatous Response to Mycobacterium bovis BCG Infection In Vivo by ROACH, D. R, BRISCOE, H, BAUMGART, K, RATHJEN, D. A, BRITTON, W. J

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A Tumor Necrosis Factor Mimetic Peptide Activates a Murine Macrophage Cell Line To Inhibit Mycobacterial Growth in a Nitric Oxide-Dependent Fashion by BRITTON, W. J, MEADOWS, N, RATHJEN, D. A, ROACH, D. R, BRISCOE, H

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A novel long chain polyunsaturated fatty acid, beta-Oxa 21:3n-3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals by Costabile, M, Hii, C S, Robinson, B S, Rathjen, D A, Pitt, M, Easton, C, Miller, R C, Poulos, A, Murray, A W, Ferrante, A

“…A novel polyunsaturated fatty acid (PUFA), beta-oxa 21:3n-3, containing an oxygen atom in the beta position, was chemically synthesized, and found to have more…”
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Enhancement of Lipopolysaccharide-Induced Neutrophil Oxygen Radical Production by Tumor Necrosis Factor Alpha by JERSMANN, H. P. A, RATHJEN, D. A, FERRANTE, A

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Killing of Staphylococcus aureus by tumor necrosis factor-alpha- activated neutrophils. The role of serum opsonins, integrin receptors, respiratory burst, and degranulation by Ferrante, A, Martin, AJ, Bates, EJ, Goh, DH, Harvey, DP, Parsons, D, Rathjen, DA, Russ, G, Dayer, JM

“…We have examined the effects of TNF priming on the killing of Staphylococcus aureus by human neutrophils. In the absence of serum opsonins, neutrophils failed…”
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Effects of granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), IL‐2, interferon‐gamma (IFN‐γ), tumour necrosis factor‐alpha (TNF‐α) and IL‐6 on the production of immunoreactive IL‐1 and TNF‐α by human monocytes by DANIS, V. A., FRANIC, G. M., RATHJEN, D. A., BROOKS, P. M.

“…SUMMARY The effects of GM‐CSF, IL‐2, IFN‐γ, TNF‐α and IL‐6 on the production of IL‐1 (both secreted and cell associated) and TNF‐α by peripheral blood…”
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Differential effects of small tumour necrosis factor-α peptides on tumour cell cytotoxicity, neutrophil activation and endothelial cell procoagulant activity by RATHJEN, D. A, FERRANTE, A, ASTON, R

“…Tumour necrosis factor-alpha (TNF-alpha) is a pluripotent cytokine with its receptors distributed throughout many different cell types. Because of the diverse…”
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Rapid degradation of articular cartilage proteoglycan by neutrophils: comparison with macrophages and synovial fibroblasts by Halliday, D A, Clemente, G, Rathjen, D A, Ferrante, A

“…To determine and compare the proteoglycan degradative properties of neutrophils, macrophages and synoviocytes in cultures of articular cartilage. MATERIAL OF…”
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Selective enhancement of the tumour necrotic activity of TNFα with monoclonal antibody by RATHJEN, D. A, FURPHY, L. J, ASTON, R

“…The binding and biological activity of human TNF alpha on endothelial and tumour cells has been studied in the presence of monoclonal antibodies (MAbs). In…”
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Effects of β‐oxa and β‐thia polyunsaturated fatty acids on agonist‐induced increase in endothelial cell adhesion molecules by Robinson, B. S., Huang, Z. H., Parashakis, G., Hii, C. S. T., Ferrante, J. V., Poulos, A., Rathjen, D. A., Pitt, M. J., Easton, C. J., Ferrante, A.

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Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases by Hii, C S, Huang, Z H, Bilney, A, Costabile, M, Murray, A W, Rathjen, D A, Der, C J, Ferrante, A

“…Although it is well appreciated that arachidonic acid, a second messenger molecule that is released by ligand-stimulated phospholipase A2, stimulates a wide…”
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Interaction of Staphylococcus aureus with human neutrophils and the down-regulation of TNF receptors by Ferrante, A, Martin, AJ, Bates, EJ, Kowanko, IC, Harvey, DP, Parsons, D, Rathjen, DA, Russ, G, Dayer, JM

“…We have shown previously that pre-exposure of neutrophils to TNF significantly enhanced their killing of opsonized Staphylococcus aureus. We now demonstrate…”
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Antigenic structure of human tumour necrosis factor: recognition of distinct regions of TNF alpha by different tumour cell receptors by Rathjen, D A, Cowan, K, Furphy, L J, Aston, R

“…TNF alpha is a cytokine which causes cytolysis of tumour cell lines in vitro as well as haemorrhagic necrosis of many transplanted tumours in vivo. In…”
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Optimization of conditions for in vitro antigenic stimulation of dissociated mouse spleen cells for the production of monoclonal antibodies against peptide hormones by Rathjen, D A, Underwood, P A

“…Factors affecting hybridoma yield following in vitro immunization have been investigated. Of critical importance for optimum yield was the batch of young calf…”
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Antigenic structure of bovine growth hormone: location of a growth enhancing region by Aston, R, Rathjen, D A, Holder, A T, Bender, V, Trigg, T E, Cowan, K, Edwards, J A, Cowden, W B

“…Site-directed antisera generated by peptide immunization have been used to study the antigenicity of bovine growth hormone (bGH). Prediction of sequential…”
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Circulating cytokine levels in patients with rheumatoid arthritis: results of a double blind trial with sulphasalazine by Danis, V A, Franic, G M, Rathjen, D A, Laurent, R M, Brooks, P M

“…Interleukin 1 (IL-1), IL-6, and tumour necrosis factor (TNF) alpha are pleiotropic cytokines produced predominantly by macrophages which have been implicated…”
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The production of monoclonal antibodies to human chorionic gonadotrophin and its subunits by Stuart, M C, Underwood, P A, Harman, D F, Payne, K L, Rathjen, D A, Razziudin, S, Von Sturmer, S R, Vines, K

“…The difficulties encountered in producing highly specific antisera to human chorionic gonadotrophin (hCG) were overcome by the use of hybridoma technology. A…”
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Activation of Mitogen-activated Protein Kinase by Arachidonic Acid in Rat Liver Epithelial WB Cells by a Protein Kinase C-dependent Mechanism (∗) by Hii, Charles S.T., Ferrante, Antonio, Edwards, Yasmin S., Huang, Zhi H., Hartfield, Perry J., Rathjen, Deborah A., Poulos, Alf, Murray, Andrew W.

“…Arachidonic acid (20:4(n-6)), which is released by cells responding to a wide range of stimuli, may play an important role in intracellular signaling. We now…”
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Identification of antigenic determinants on insulin recognized by monoclonal antibodies by Rathjen, D A, Underwood, P A

“…The specificities of nine monoclonal antibodies raised to bovine insulin were investigated. The probable binding sites of the antibodies were determined by…”
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Altered responses of human macrophages to lipopolysaccharide by hydroperoxy eicosatetraenoic acid, hydroxy eicosatetraenoic acid, and arachidonic acid. Inhibition of tumor necrosis factor production by Ferrante, J V, Huang, Z H, Nandoskar, M, Hii, C S, Robinson, B S, Rathjen, D A, Poulos, A, Morris, C P, Ferrante, A

“…The regulation of allergic and autoimmune inflammatory reactions by polyunsaturated fatty acids and their metabolic products (eicosanoids) continues to be of…”
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