Search Results - "RASO, Erzsebet"
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1
Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series
Published in Journal of translational medicine (13-02-2024)“…The tumor-agnostic indication of immune checkpoint inhibitors to treat cancers with mismatch repair deficiency (dMMR)/microsatellite instability (MSI)…”
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2
Identification of a Tumor Cell Associated Type I IFN Resistance Gene Expression Signature of Human Melanoma, the Components of Which Have a Predictive Potential for Immunotherapy
Published in International journal of molecular sciences (28-02-2022)“…We developed a human melanoma model using the HT168-M1 cell line to induce IFN-α2 resistance in vitro (HT168-M1res), which was proven to be maintained in vivo…”
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3
Frequent KIT mutations in skin lesions of patients with BRAF wild-type Langerhans cell histiocytosis
Published in Virchows Archiv : an international journal of pathology (01-11-2020)“…Langerhans cell histiocytosis (LCH) is characterized by mutations of the RAS-RAF-MAPK signaling pathway. We analyzed MAP2K1, NRAS and KIT mutation incidence in…”
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4
Characteristics of CD44 alternative splice pattern in the course of human colorectal adenocarcinoma progression
Published in Molecular cancer (14-11-2012)“…CD44 is considered as 'a' metastasis associated gene, despite the fact that it is an umbrella term for a group of molecules produced from a single gene by…”
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5
The importance of microenvironment: the role of CCL8 in metastasis formation of melanoma
Published in Oncotarget (06-10-2015)“…We have attempted to characterize the changes occurring on the host side during the progression of human melanoma. To investigate the role of tumor…”
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6
Analysis of colorectal adenocarcinoma tissue by desorption electrospray ionization mass spectrometric imaging
Published in Analytical and bioanalytical chemistry (01-06-2012)“…Negative ion desorption electrospray ionization (DESI) was used for the analysis of an ex vivo tissue sample set comprising primary colorectal adenocarcinoma…”
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7
Erlotinib as single agent first line treatment in locally advanced or metastatic activating EGFR mutation-positive lung adenocarcinoma (CEETAC): an open-label, non-randomized, multicenter, phase IV clinical trial
Published in BMC cancer (25-05-2018)“…Erlotinib is approved for the first line treatment of epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer. Since the number of…”
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8
Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma
Published in Journal of thoracic oncology (01-05-2015)“…Although classic sensitizing mutations of epidermal growth factor receptor (EGFR) are positive predictive markers for EGFR tyrosine kinase inhibitors (TKIs) in…”
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9
Tumor necrosis correlates with PD-L1 and PD-1 expression in lung adenocarcinoma
Published in Acta oncologica (03-08-2019)“…Predictive biomarkers for immunotherapy in lung cancer are intensively investigated; however, correlations between PD-L1/PD-1 expressions and clinical features…”
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10
Renal Cell Carcinoma with Clear Cell Papillary Features: Perspectives of a Differential Diagnosis
Published in Pathology oncology research (01-07-2020)“…Thirty-one cases of low-grade renal cell carcinoma (RCC) with clear cells and tubulopapillary/papillary architecture were analyzed retrospectively with…”
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11
Aquaporin 1 protein expression is associated with BRAF V600 mutation and adverse prognosis in cutaneous melanoma
Published in Melanoma research (01-06-2016)“…Despite experimental findings suggesting the prognostic significance of Aquaporin 1 (AQP1) in human melanoma, no published clinical data are available. We…”
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12
Identification and clinical significance of circulating endothelial progenitor cells in human non-small cell lung cancer
Published in Cancer research (Chicago, Ill.) (15-07-2006)“…Until recently, it was generally accepted that vascularization of tumors arises exclusively from endothelial sprouting. Whether circulating bone marrow-derived…”
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13
Demonstration of a melanoma-specific CD44 alternative splicing pattern that remains qualitatively stable, but shows quantitative changes during tumour progression
Published in PloS one (14-01-2013)“…The role of CD44 in the progression of human melanoma has mostly been characterised by qualitative changes in expression of its individual variable exons…”
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14
EGFR Alterations Influence the Cetuximab Treatment Response and c-MET Tyrosine-Kinase Inhibitor Sensitivity in Experimental Head and Neck Squamous Cell Carcinomas
Published in Pathology oncology research (03-05-2021)“…Anti-EGFR antibody therapy is still one of the clinical choices in head and neck squamous cell carcinoma (HNSCC) patients, but the emergence of cetuximab…”
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15
EGFR R521K Polymorphism Is Not a Major Determinant of Clinical Cetuximab Resistance in Head and Neck Cancer
Published in Cancers (13-05-2022)“…Head and neck squamous cell carcinomas (HNSCCs) are among the most abundant malignancies worldwide. Patients with recurrent/metastatic disease undergo…”
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16
Recombinant human erythropoietin alpha targets intratumoral blood vessels, improving chemotherapy in human xenograft models
Published in Cancer research (Chicago, Ill.) (15-08-2005)“…Recombinant human erythropoietin (rHuEPO) is widely used for correction of hemoglobin level in cancer patients. However, apart from hematopoiesis, rHuEPO…”
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17
Molecular Characteristics of Fibrolamellar Hepatocellular Carcinoma
Published in Pathology oncology research (01-01-2013)“…Fibrolamellar hepatocellular carcinoma (FLC) occurs in non-cirrhotic liver and the etiopathogenesis is still obscure. Both hepatocellular and cholangiocellular…”
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18
Sex-dependent liver colonization of human melanoma in SCID mice—role of host defense mechanisms
Published in Clinical & experimental metastasis (01-04-2013)“…The possibility that endocrine factors may influence the clinical course of malignant melanoma is suggested by the superior survival data of women. In…”
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19
Revisiting CB1 Receptor as Drug Target in Human Melanoma
Published in Pathology oncology research (01-10-2012)“…Previous studies have indicated the antitumoral effect of human melanocytes, human melanoma cell lines expressing CB1 receptor (CB1), and of the peritumoral…”
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20
Recombinant Human Erythropoietin alpha Improves the Efficacy of Radiotherapy of a Human Tumor Xenograft, Affecting Tumor Cells and Microvessels
Published in Strahlentherapie und Onkologie (2008)“…Background and Purpose: Tumor-induced anemia often occurs in cancer patients, and is corrected by recombinant human erythropoietins (rHuEPOs). Recent studies…”
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