Search Results - "RANDINITIS, E. J"

Effect of food on absorption of Dilantin Kapseals and Mylan extended phenytoin sodium capsules by Wilder, B J, Leppik, I, Hietpas, T J, Cloyd, J C, Randinitis, E J, Cook, J

“…Because of phenytoin's narrow therapeutic index and nonlinear pharmacokinetics, food-induced alterations in absorption may markedly influence drug…”
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Steady-State Pharmacokinetics and Dose Proportionality of Troglitazone and Its Metabolites by Loi, Cho-Ming, Alvey, Christine W., Vassos, Artemios B., Randinitis, Edward J., Sedman, Allen J., Koup, Jeffrey R.

“…This study evaluated the steady‐state pharmacokinetics and dose proportionality of troglitazone, metabolite 1 (sulfate conjugate), and metabolite 3 (quinone…”
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Single-Dose Gabapentin Pharmacokinetics and Safety in Healthy Infants and Children by Haig, George M., Bockbrader, Howard N., Wesche, David L., Boellner, Samuel W., Ouellet, Daniele, Brown, Richard R., Randinitis, Edward J., Posvar, Edward L.

“…Gabapentin (Neurontin®) is a gamma‐aminobutyric acid analogue indicated in adults for adjunctive treatment of partial seizures with or without secondary…”
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Drug Interactions with Clinafloxacin by RANDINITIS, Edward J, ALVEY, Christine W, KOUP, Jeffery R, RAUSCH, George, ABEL, Robert, BRON, Nicola J, HOUNSLOW, Neil J, VASSOS, Artemios B, SEDMAN, Allen J

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Pharmacokinetics of Clinafloxacin after Single and Multiple Doses by RANDINITIS, Edward J, BRODFUEHRER, Joanne I, EISEMAN, Irene, VASSOS, Artemios B

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Gabapentin does not interact with a contraceptive regimen of norethindrone acetate and ethinyl estradiol by ELDON, M. A, UNDERWOOD, B. A, RANDINITIS, E. J, SEDMAN, A. J

“…Anticonvulsants that induce hepatic metabolism increase clearance of oral contraceptive hormones and thereby cause contraceptive failure. Gabapentin is not…”
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Clinafloxacin Pharmacokinetics in Subjects with Various Degrees of Renal Function by RANDINITIS, Edward J, KOUP, Jeffery R, RAUSCH, George, ABEL, Robert, BRON, Nicola J, HOUNSLOW, Neil J, VASSOS, Artemios B, SEDMAN, Allen J

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Pharmacokinetics of Clinafloxacin Enantiomers in Humans by Humphrey, Gaye H., Shapiro, Martin A., Randinitis, Edward J., Guttendorf, Robert J., Brodfuehrer, Joanne I.

“…The pharmacokinetics of R‐clinafloxacin and S‐clinafloxacin enantiomers of the broad‐spectrum fluoroquinolone antibiotic, clinafloxacin, were characterized in…”
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Lack of Effect of Type II Diabetes on the Pharmacokinetics of Troglitazone in a Multiple-Dose Study by Loi, Cho-Ming, Randinitis, Edward J., Vassos, Artemios B., Kazierad, David J., Koup, Jeffrey R., Sedman, Allen J.

“…Twelve patients with type II diabetes and 12 age‐, weight‐, and gender‐matched healthy subjects participated in a study comparing the pharmacokinetics of…”
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Meta-Analysis of Steady-State Pharmacokinetics of Troglitazone and Its Metabolites by Loi, Cho-Ming, Alvey, Christine W., Randinitis, Edward J., Abel, Robert, Young, Malcolm A., Koup, Jeffrey R.

“…The object of this study is to evaluate the effects of age, gender, age‐by‐gender interaction, Type II diabetes, body weight, race, smoking, and formulation on…”
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Lack of a pharmacokinetic interaction between azithromycin and chloroquine by Cook, Jack A, Randinitis, Edward J, Bramson, Candace R, Wesche, David L

“…A study was conducted to investigate a possible pharmacokinetic interaction between azithromycin and chloroquine. Twenty-four subjects received azithromycin,…”
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Effect of Troglitazone on Steady-State Pharmacokinetics of Digoxin by Loi, Cho-Ming, Knowlton, Philip W., Stern, Ralph, Randinitis, Edward J., Vassos, Artemios B., Koup, Jeffrey R., Sedman, Allen J.

“…Twelve healthy subjects participated in a study to determine the effect of multiple doses of troglitazone on the steady‐state pharmacokinetics of digoxin…”
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Pregabalin Drug Interaction Studies: Lack of Effect on the Pharmacokinetics of Carbamazepine, Phenytoin, Lamotrigine, and Valproate in Patients with Partial Epilepsy by Brodie, Martin J., Wilson, Elaine A., Wesche, David L., Alvey, Christine W., Randinitis, Edward J., Posvar, Edward L., Hounslow, Neil J., Bron, Nicola J., Gibson, G. L., Bockbrader, Howard N.

“…Purpose: Pregabalin (PGB) is an α2‐δ ligand with demonstrated efficacy in epilepsy, neuropathic pain, and anxiety disorders. PGB is highly efficacious as…”
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A high-performance liquid chromatographic assay for the enantiomers of bevantolol in human plasma by ROSE, S. E, RANDINITIS, E. J

“…A method was developed and validated for the simultaneous analysis of (+)- and (-)-bevantolol in human plasma. The assay involves plasma protein precipitation,…”
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Effect of a high-fat meal on the bioavailability of a polymer-coated erythromycin particle tablet formulation by Randinitis, E J, Sedman, A J, Welling, P G, Kinkel, A W

“…The effect of food on the relative bioavailability of an erythromycin particles-in-tablet formulation was studied in 27 healthy volunteers, using a four-way,…”
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Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium by Conroy, M C, Randinitis, E J, Turner, J L

“…Meclofenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) approved for use in arthritis (osteo and rheumatoid), analgesia (mild to moderate pain),…”
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Pharmacokinetic profile of a 300-mg extended phenytoin sodium capsule (Dilantin) formulation by Randinitis, E J, Buchanan, R A, Kinkel, A W

“…The pharmacokinetic profile of a newly developed Dilantin 300-mg Kapseal formulation was compared with that of currently marketed Dilantin 100-mg Kapseals in…”
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Liquid chromatographic determination of gemfibrozil and its metabolite in plasma by Randinitis, E J, Parker, 3rd, T D, Kinkel, A W

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Gas chromatographic determination of gemfibrozil and its metabolites in plasma and urine by Randinitis, E J, Kinkel, A W, Nelson, C, Parker, 3rd, T D

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Gas chromatographic determination of bevantolol in plasma by Randinitis, E J, Nelson, C, Kinkel, A W

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