Search Results - "RANDELL, Jukka"

Reticulation pattern without honeycombing on high-resolution CT is associated with the risk of disease progression in interstitial lung diseases by Mononen, Minna, Saari, Eeva, Hasala, Hannele, Kettunen, Hannu-Pekka, Suoranta, Sanna, Nurmi, Hanna, Kärkkäinen, Miia, Selander, Tuomas, Randell, Jukka, Laurikka, Jari, Uibu, Toomas, Koskela, Heikki, Kaarteenaho, Riitta, Purokivi, Minna

“…Abstract Background The disease course of idiopathic pulmonary fibrosis (IPF) is progressive and occasionally, other types of interstitial lung disease (ILD)…”
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Human CD4+ T cell responses to the dog major allergen Can f 1 and its human homologue tear lipocalin resemble each other by Liukko, Aino L K, Kinnunen, Tuure T, Rytkönen-Nissinen, Marja A, Kailaanmäki, Anssi H T, Randell, Jukka T, Maillère, Bernard, Virtanen, Tuomas I

“…Lipocalin allergens form a notable group of proteins, as they contain most of the significant respiratory allergens from mammals. The basis for the allergenic…”
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Characterization of human memory CD4+ T-cell responses to the dog allergen Can f 4 by Rönkä, Aino L., MD, Kinnunen, Tuure T., MD, PhD, Goudet, Amélie, BSc, Rytkönen-Nissinen, Marja A., PhD, Sairanen, Joni, BM, Kailaanmäki, Anssi H.T., MSc, Randell, Jukka T., MD, PhD, Maillère, Bernard, PhD, Virtanen, Tuomas I., MD, PhD

“…Background The recently identified dog lipocalin allergen Can f 4 is an important respiratory allergen. Objective We sought to comprehensively characterize the…”
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IgE Reactivity of the Dog Lipocalin Allergen Can f 4 and the Development of a Sandwich ELISA for Its Quantification by Rytkönen-Nissinen, Marja, Saarelainen, Soili, Randell, Jukka, Häyrinen, Jukka, Kalkkinen, Nisse, Virtanen, Tuomas

“…Divergent results on the IgE reactivity of dog-allergic subjects to Can f 4 have been reported. The aim of this study was to evaluate the significance of Can f…”
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Interpretation of cough provoked by airway challenges by Koskela, Heikki O, Kontra, Kirsi M, Purokivi, Minna K, Randell, Jukka T

“…To analyze the cough response to three airway challenges in order to clarify whether the recording of the provoked coughs would be beneficial in the management…”
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Health risk assessment of indoor air pollution in Finnish ice arenas by Salonen, Raimo O., Pennanen, Arto S., Vahteristo, Mikko, Korkeila, Petri, Alm, Sari, Randell, Jukka T.

“…Poor indoor air quality and epidemic carbon monoxide (CO) and nitrogen dioxide (NO2) poisonings due to exhaust emissions from ice resurfacers have been…”
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Cholesterol Metabolism and Weight Reduction in Subjects with Mild Obstructive Sleep Apnoea: A Randomised, Controlled Study by Hallikainen, Maarit, Tuomilehto, Henri, Martikainen, Tarja, Vanninen, Esko, Seppä, Juha, Kokkarinen, Jouko, Randell, Jukka, Gylling, Helena

“…To evaluate whether parameters of obstructive sleep apnoea (OSA) associate with cholesterol metabolism before and after weight reduction, 42 middle-aged…”
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Nasal Lavage Method in the Monitoring of Upper Airway Inflammation: Seasonal and Individual Variation by Roponen, Marjut, Seuri, Markku, Nevalainen, Aino, Randell, Jukka, Hirvonen, Maija-Riitta

“…A noninvasive and reliable method is needed to investigate causal relationship between exposure to bioaerosols in occupational and indoor environments and…”
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Hypertonicity of the challenge solution may increase the diagnostic accuracy of histamine challenge by Koskela, Heikki O., Kontra, Kirsi M., Purokivi, Minna K., Randell, Jukka T.

“…There is significant overlap in the responsiveness to direct airway challenges, such as the histamine challenge, between asthmatic and non-asthmatic subjects,…”
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Single-cell characterization of dog allergen–specific T cells reveals TH2 heterogeneity in allergic individuals by Vandamme, Céline, Rytkönen-Nissinen, Marja, Lönnberg, Tapio, Randell, Jukka, Harvima, Rauno J., Kinnunen, Tuure, Virtanen, Tuomas

“…Allergen-specific type 2 CD4+ TH2 cells are critically involved in the pathogenesis of IgE-mediated allergic diseases. However, the heterogeneity of the TH2…”
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Risk factors of clinically significant complications in transbronchial lung cryobiopsy: A prospective multi-center study by Mononen, Minna, Saari, Eeva, Hasala, Hannele, Kettunen, Hannu-Pekka, Suoranta, Sanna, Nurmi, Hanna, Randell, Jukka, Laurikka, Jari, Uibu, Toomas, Koskela, Heikki, Kaarteenaho, Riitta, Purokivi, Minna

“…The use of a transbronchial lung cryobiopsy (TBLC) is increasing as a diagnostic method of interstitial lung diseases (ILD). This study aimed to evaluate risk…”
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Lifestyle Intervention with Weight Reduction: First-line Treatment in Mild Obstructive Sleep Apnea by Tuomilehto, Henri P. I, Seppa, Juha M, Partinen, Markku M, Peltonen, Markku, Gylling, Helena, Tuomilehto, Jaakko O. I, Vanninen, Esko J, Kokkarinen, Jouko, Sahlman, Johanna K, Martikainen, Tarja, Soini, Erkki J. O, Randell, Jukka, Tukiainen, Hannu, Uusitupa, Matti, on behalf of Kuopio Sleep Apnea Group

“…Obesity is the most important risk factor for obstructive sleep apnea (OSA). However, although included in clinical guidelines, no randomized controlled…”
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Sustained improvement in mild obstructive sleep apnea after a dietand physical activity-based lifestyle intervention: postinterventional follow-up by TUOMILEHTO, Henri, GYLLING, Helena, TUOMILEHTO, Jaakko, UUSITUPA, Matti, PELTONEN, Markku, MARTIKAINEN, Tarja, SAHLMAN, Johanna, KOKKARINEN, Jouko, RANDELL, Jukka, TUKIAINEN, Hannu, VANNINEN, Esko, PARTINEN, Markku

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Single-cell characterization of dog allergen-specific T cells reveals T H 2 heterogeneity in allergic individuals by Vandamme, Céline, Rytkönen-Nissinen, Marja, Lönnberg, Tapio, Randell, Jukka, Harvima, Rauno J, Kinnunen, Tuure, Virtanen, Tuomas

“…Allergen-specific type 2 CD4 T 2 cells are critically involved in the pathogenesis of IgE-mediated allergic diseases. However, the heterogeneity of the T 2…”
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The impact of weight reduction in the prevention of the progression of obstructive sleep apnea: an explanatory analysis of a 5-year observational follow-up trial by Tuomilehto, Henri, Seppä, Juha, Uusitupa, Matti, Peltonen, Markku, Martikainen, Tarja, Sahlman, Johanna, Kokkarinen, Jouko, Randell, Jukka, Pukkila, Matti, Vanninen, Esko, Tuomilehto, Jaakko, Gylling, Helena

“…Highlights • Obstructive sleep apnea (OSA) is a chronic progressive disease. • Severe OSA is associated with an increased risk for cardiovascular morbidity and…”
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Sustained improvement in mild obstructive sleep apnea after a diet- and physical activity-based lifestyle intervention: postinterventional follow-up by Tuomilehto, Henri, Gylling, Helena, Peltonen, Markku, Martikainen, Tarja, Sahlman, Johanna, Kokkarinen, Jouko, Randell, Jukka, Tukiainen, Hannu, Vanninen, Esko, Partinen, Markku, Tuomilehto, Jaakko, Uusitupa, Matti, Seppä, Juha

“…BACKGROUND: Obesity is the most important risk factor for obstructive sleep apnea (OSA). Weight-reduction programs have been observed to represent effective…”
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Short-term and seasonal variations of exhaled and nasal NO in healthy subjects by Stark, Harri, Purokivi, Minna, Kiviranta, Jukka, Randell, Jukka, Tukiainen, Hannu

“…Summary Nitric oxide (NO) is an important biological mediator with a variety of cellular and tissue functions. Fractional exhaled (FENO ) and nasal NO (FNNO )…”
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Differential CD 4 + T ‐cell responses of allergic and non‐allergic subjects to the immunodominant epitope region of the horse major allergen E qu c  1 by Kailaanmäki, Anssi, Kinnunen, Tuure, Kwok, William W., Rytkönen‐Nissinen, Marja, Randell, Jukka, Virtanen, Tuomas

“…Summary The responses of allergen‐specific CD 4 + T cells of allergic and healthy individuals are still incompletely understood. Our objective was to…”
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Human CD4.sup.+ T Cell Responses to the Dog Major Allergen Can f 1 and Its Human Homologue Tear Lipocalin Resemble Each Other by Liukko, Aino L. K, Kinnunen, Tuure T, Rytkönen-Nissinen, Marja A, Kailaanmäki, Anssi H. T, Randell, Jukka T, Maillère, Bernard, Virtanen, Tuomas I

“…Lipocalin allergens form a notable group of proteins, as they contain most of the significant respiratory allergens from mammals. The basis for the allergenic…”
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Differential CD4+ T‐cell responses of allergic and non‐allergic subjects to the immunodominant epitope region of the horse major allergen Equ c 1 by Kailaanmäki, Anssi, Kinnunen, Tuure, Kwok, William W., Rytkönen‐Nissinen, Marja, Randell, Jukka, Virtanen, Tuomas

“…Summary The responses of allergen‐specific CD4+ T cells of allergic and healthy individuals are still incompletely understood. Our objective was to investigate…”
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