Search Results - "RAMSDEN, R. T"

Malignant transformation and new primary tumours after therapeutic radiation for benign disease: substantial risks in certain tumour prone syndromes by Evans, D G R, Birch, J M, Ramsden, R T, Sharif, S, Baser, M E

“…In recent years the use of radiation treatment for benign tumours has increased with the advent of stereotactic delivery and, in particular, single high dose…”
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Mosaicism in neurofibromatosis type 2: an update of risk based on uni/bilaterality of vestibular schwannoma at presentation and sensitive mutation analysis including multiple ligation-dependent probe amplification by Evans, D Gareth R, Ramsden, R T, Shenton, A, Gokhale, C, Bowers, N L, Huson, S M, Pichert, G, Wallace, A

“…Background: Neurofibromatosis type 2 (NF2) is almost unique among inherited disorders in the frequency of mosaicism in the first affected generation. However,…”
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Evaluation of clinical diagnostic criteria for neurofibromatosis 2 by BASER, M. E, FRIEDMAN, J. M, WALLACE, A. J, RAMSDEN, R. T, JOE, H, EVANS, D. G. R

“…Four sets of clinical diagnostic criteria for neurofibromatosis 2 (NF2) have been developed by groups of expert clinicians, but sensitivity has never been…”
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Further genotype - phenotype correlations in neurofibromatosis 2 by Selvanathan, SK, Shenton, A, Ferner, R, Wallace, AJ, Huson, SM, Ramsden, RT, Evans, DG

“…Selvanathan SK, Shenton A, Ferner R, Wallace AJ, Huson SM, Ramsden RT, Evans DG. Further genotype–phenotype correlations in neurofibromatosis 2…”
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Bilateral vestibular schwannomas in older patients: NF2 or chance? by Evans, D G, Freeman, S, Gokhale, C, Wallace, A, Lloyd, S K, Axon, P, Ward, C L, Rutherford, S, King, A, Huson, S M, Ramsden, R T

“…Neurofibromatosis type 2 (NF2) is an autosomal dominant condition with high spontaneous mutation rate which predisposes to the development of multiple nerve…”
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The location of constitutional neurofibromatosis 2 (NF2) splice site mutations is associated with the severity of NF2 by Baser, M E, Kuramoto, L, Woods, R, Joe, H, Friedman, J M, Wallace, A J, Ramsden, R T, Olschwang, S, Bijlsma, E, Kalamarides, M, Papi, L, Kato, R, Carroll, J, Lázaro, C, Joncourt, F, Parry, D M, Rouleau, G A, Evans, D G R

“…Neurofibromatosis 2 (NF2) patients with constitutional splice site NF2 mutations have greater variability in disease severity than NF2 patients with other…”
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Use of a closed set questionnaire to measure primary and secondary effects of neurofibromatosis type 2 by Neary, W J, Hillier, V F, Flute, T, Stephens, D, Ramsden, R T, Evans, D G R

“…To identify the greatest difficulties reported by people affected by neurofibromatosis type 2, and to determine the relationship between the primary and…”
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Paediatric presentation of type 2 neurofibromatosis by Evans, D G R, Birch, J M, Ramsden, R T

“…BACKGROUND Neurofibromatosis type 2 (NF2) is a highly penetrant autosomal dominant condition predisposing affected individuals to schwannomas and meningiomas…”
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Somatic mosaicism in neurofibromatosis 2: prevalence and risk of disease transmission to offspring by Moyhuddin, A, Baser, M E, Watson, C, Purcell, S, Ramsden, R T, Heiberg, A, Wallace, A J, Evans, D G R

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Vestibular schwannoma: role of conservative management by Suryanarayanan, R, Ramsden, R T, Saeed, S R, Aggarwal, R, King, A T, Rutherford, S A, Evans, D G, Gillespie, J E

“…To assess the outcome of conservative management of vestibular schwannoma. Observational study. Tertiary referral centre. Four hundred and thirty-six patients…”
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Should NF2 mutation screening be undertaken in patients with an apparently isolated vestibular schwannoma? by Evans, DGR, Ramsden, RT, Gokhale, C, Bowers, N, Huson, SM, Wallace, A

“…Early onset of vestibular schwannoma (VS) is associated with the inherited condition neurofibromatosis type 2 (NF2). However, the majority of NF2 presents…”
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Complications following adult cochlear implantation: experience in Manchester by Green, K M J, Bhatt, Y M, Saeed, S R, Ramsden, R T

“…Cochlear implantation is regarded as a safe and effective treatment for the profoundly deaf. However, a proportion of patients suffer complications after…”
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Intracochlear Factors Contributing to Psychophysical Percepts Following Cochlear Implantation by KAWANO, A, SELDON, H. L, CLARK, G. M, RAMSDEN, R. T, RAINE, C. H

“…The performance of cochlear implant patients may be related to intracochlear, histopathological factors. We have performed detailed post-mortem examinations of…”
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Cochlear implant outcomes and quality of life in the elderly: Manchester experience over 13 years by Orabi, A.A., Mawman, D., Al-Zoubi, F., Saeed, S.R., Ramsden, R.T.

“…To objectively evaluate the clinical and functional outcomes of cochlear implantation in an elderly population. Retrospective comparative study. Neurotology…”
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Identification of recurrent regions of chromosome loss and gain in vestibular schwannomas using comparative genomic hybridisation by Warren, C, James, L A, Ramsden, R T, Wallace, A, Baser, M E, Varley, J M, Evans, D G

“…Background: Schwannomas are benign tumours of the nervous system that are usually sporadic but also occur in the inherited disorder neurofibromatosis type 2…”
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Somatic mosaicism : A common cause of classic disease in tumor-prone syndromes? Lessons from type 2 neurofibromatosis by EVANS, D. G. R, WALLACE, A. J, WU, C. L, TRUEMAN, L, RAMSDEN, R. T, STRACHAN, T

“…Blood samples from 125 families with classic type 2 neurofibromatosis with bilateral vestibular schwannomas were analyzed for mutations in the NF2 gene…”
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Molecular genetic analysis of the NF2 gene in young patients with unilateral vestibular schwannomas by Mohyuddin, A, Neary, W J, Wallace, A, Wu, C L, Purcell, S, Reid, H, Ramsden, R T, Read, A, Black, G, Evans, D G R

“…Neurofibromatosis type 2 (NF2) must be suspected in patients presenting with a unilateral vestibular schwannoma at a young age who are therefore at theoretical…”
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Imaging appearances of unusual conditions of the middle and inner ear by OFFIAH, C. E, RAMSDEN, R. T, GILLESPIE, J. E

“…Requests for imaging of patients complaining of deafness and other symptoms related to the petrous bone are becoming increasingly common. Although much of this…”
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The Pakistan (Lahore) cochlear implant programme: issues relating to implantation in a developing country by Khan, M I J, Mukhtar, N, Saeed, S R, Ramsden, R T

“…The Pakistan cochlear implant programme was started in Lahore in August 2000. It was initially established with the technical support of the Manchester…”
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Metastatic carcinoma mimicking a facial nerve schwannoma: the role of computerized tomography in diagnosis by Suryanarayanan, R, Dezso, A, Ramsden, R T, Gillespie, J E

“…Secondary deposits in the temporal bone are uncommon but well recognized. Such tumours may involve the facial nerve by direct extension of the destructive…”
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