Search Results - "RAMSDEN, D. B"

Multiple sclerosis: assay of free immunoglobulin light chains by Ramsden, D B

“…Over the past five years, a number of papers have appeared describing the assay of free immunoglobulin light chains in cerebrospinal fluid to assist in the…”
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Human catechol- O-methyltransferase down-regulation by estradiol by Jiang, H, Xie, T, Ramsden, D.B, Ho, S.L

“…Catechol- O-methyltransferase (COMT) is a crucial enzyme in dopamine and levodopa metabolism. Previously we reported that physiological concentrations of…”
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Mechanisms of neurodegeneration in amyotrophic lateral sclerosis by Cluskey, S, Ramsden, D B

“…Amyotrophic lateral sclerosis (ALS) is the most common variant of motor neurone disease affecting adults that usually strikes during mid to late life. Its…”
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Huntington's disease by Davies, S, Ramsden, D B

“…The most recent findings in the elucidation of the molecular pathology of Huntington's disease are reviewed. Particular interest has been paid to the role of…”
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Parkinson's disease: the first common neurological disease due to auto-intoxication? by Williams, A.C., Cartwright, L.S., Ramsden, D.B.

“…Parkinson's disease may be a disease of autointoxication. N-methylated pyridines (e.g. MPP+) are well-established dopaminergic toxins, and the xenobiotic…”
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Hydrogen symbioses in evolution and disease by Williams, A.C., Ramsden, D.B.

“…Hydrogen is the source of energy that unites the metabolisms and fuels the innovative potentials of all living organisms. Autotrophs use hydrogen emitted into…”
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Enteral feeding reduces metabolic activity of the intestinal microbiome in Crohn’s disease: an observational study by Walton, C, Montoya, M P B, Fowler, D P, Turner, C, Jia, W, Whitehead, R N, Griffiths, L, Waring, R H, Ramsden, D B, Cole, J A, Cauchi, M, Bessant, C, Naylor, S J, Hunter, J O

“…Background/Objectives: Enteral feeding will induce remission in as many as 80–90% of compliant patients with active Crohn’s disease (CD), but its method of…”
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The effect of plasticisers on “sulphate supply” enzymes by Turan, N., Waring, R.H., Ramsden, D.B.

“…Sulphation is important in xenobiotic detoxification and in steroid and thyroid hormones synthesis, transport and metabolism. Potential endocrine disrupting…”
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A study of five candidate genes in Parkinson's disease and related neurodegenerative disorders by NICHOLL, D. J, BENNETT, P, BONUCCELLI, U, VIEREGGE, P, RAMSDEN, D. B, MECO, G, WILLIAMS, A. C, HILLER, L, BONIFATI, V, VANACORE, N, FABBRINI, G, MARCONI, R, COLOSIMO, C, LAMBERTI, P, STOCCHI, F

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Nicotinamide homeostasis: A xenobiotic pathway that is key to development and degenerative diseases by Williams, A.C., Ramsden, D.B.

“…Monkeys and man are very closely related genetically. Yet intellectually there are big differences and they suffer from a broad range of different diseases…”
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In vitro effect of the cysteine metabolites homocysteic acid, homocysteine and cysteic acid upon human neuronal cell lines by Parsons, R B, Waring, R H, Ramsden, D B, Williams, A C

“…Cysteine (CYS) is a non-essential amino acid which elicits excitotoxic properties via the N-methyl-D-aspartate (NMDA) subtype of the glutamate receptor. CYS…”
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Nicotinamide N-methyltransferase expression in SH-SY5Y neuroblastoma and N27 mesencephalic neurones induces changes in cell morphology via ephrin-B2 and Akt signalling by Thomas, M G, Saldanha, M, Mistry, R J, Dexter, D T, Ramsden, D B, Parsons, R B

“…Nicotinamide N -methyltransferase (NNMT, E.C. 2.1.1.1) N -methylates nicotinamide to produce 1-methylnicotinamide (MeN). We have previously shown that NNMT…”
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An allelic association study of monoamine oxidase B in Parkinson's disease by Ho, S L, Kapadi, A L, Ramsden, D B, Williams, A C

“…A single-stranded conformational polymorphism in the monoamine oxidase B gene was shown to be A or G, 36 bases upstream from the intron 13-exon 14 boundary. An…”
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Uncoupling proteins: Targets of endocrine disruptors? by Pawade, T., Ho, P.W.L., Kwok, K.H.-H., Chu, A.C.-Y., Ho, S.-L., Ramsden, D.B.

“…The roles of uncoupling proteins (UCPs) are discussed. Particular attention has been paid to the roles of UCP2 to UCP5 as agents mediating thermogenesis, and…”
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Progressive supranuclear palsy by Tawana, K, Ramsden, D B

“…This review concentrates on the molecular pathology of the protein τ, including its expression in various regions of the brain. The role of post-translational…”
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Selegiline increases heme oxygenase-1 expression and the cytotoxicity produced by dopamine treatment of neuroblastoma SK-N-SH cells by Rieder, C R M, Williams, A C, Ramsden, D B

“…Increased dopamine catabolism may be associated with oxidative stress and neuronal cell death in Parkinson's disease. The present study was carried out to…”
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The aetiology of idiopathic Parkinson's disease by Ramsden, D B, Parsons, R B, Ho, S L, Waring, R H

“…Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr…”
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Neuromyelitis optica-IgG in idiopathic inflammatory demyelinating disorders amongst Hong Kong Chinese by Chan, K. H., Ramsden, D. B., Yu, Y. L., Kwok, K. H. H., Chu, A. C. Y., Ho, P. W. L., Kwan, J. S. C., Lee, R., Lim, E., Kung, M. H. W., Ho, S. L.

“…Background:  Idiopathic inflammatory demyelinating disorders (IIDD) affect the central nervous system. In classical multiple sclerosis (CMS), brain, optic…”
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Cysteine dioxygenase: Regional localisation of protein and mRNA in rat brain by Parsons, R.B., Waring, R.H., Williams, A.C., Ramsden, D.B.

“…Cysteine dioxygenase (CDO) converts cysteine to cysteinesulphinic acid and is the rate‐limiting step in sulphate production. Most studies have centred upon the…”
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An inherited non-amyloidogenic transthyretin variant, [Ser6]-TTR, with increased thyroxine-binding affinity, characterized by DNA sequencing by Fitch, N J, Akbari, M T, Ramsden, D B

“…Amplification and sequencing of the four transthyretin (TTR) exons of a subject with a variant TTR with four-fold increased affinity for thyroxine revealed a…”
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