Search Results - "RAMPTON, D. S."

Psychological stress in IBD: new insights into pathogenic and therapeutic implications by Mawdsley, J E, Rampton, D S

“…Psychological stress has long been reported anecdotally to increase disease activity in inflammatory bowel disease (IBD), and recent well designed studies have…”
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Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease by Rovedatti, L, Kudo, T, Biancheri, P, Sarra, M, Knowles, C H, Rampton, D S, Corazza, G R, Monteleone, G, Di Sabatino, A, Macdonald, T T

“…Interleukin 17 (IL17) is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in…”
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Systematic review: Clostridium difficile and inflammatory bowel disease by Goodhand, J. R., Alazawi, W., Rampton, D. S.

“…Summary Background  There is increasing concern about the apparently rising incidence and worsening outcome of Clostridium difficile infection (CDI) associated…”
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Factors associated with thiopurine non‐adherence in patients with inflammatory bowel disease by Goodhand, J. R., Kamperidis, N., Sirwan, B., Macken, L., Tshuma, N., Koodun, Y., Chowdhury, F. A., Croft, N. M., Direkze, N., Langmead, L., Irving, P. M., Rampton, D. S., Lindsay, J. O.

“…Summary Background Medication non‐adherence seems to be a particular problem in younger patients with inflammatory bowel disease (IBD) and has a negative…”
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Anti‐inflammatory effects of aloe vera gel in human colorectal mucosa in vitro by Langmead, L., Makins, R. J., Rampton, D. S.

“…Summary Background : Oral aloe vera gel is widely used by patients with inflammatory bowel disease and is under therapeutic evaluation for this condition. Aim…”
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Review article: complementary and alternative therapies for inflammatory bowel disease by LANGMEAD, L., RAMPTON, D. S.

“…Summary Complementary and alternative medicine includes a wide range of practices and therapies outside the realms of conventional western medicine. Despite a…”
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Intestinal luminal pH in inflammatory bowel disease: possible determinants and implications for therapy with aminosalicylates and other drugs by NUGENT, S G, KUMAR, D, RAMPTON, D S, EVANS, D F

“…Measurements of luminal pH in the normal gastrointestinal tract have shown a progressive increase in pH from the duodenum to the terminal ileum, a decrease in…”
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Randomized, double‐blind, placebo‐controlled trial of oral aloe vera gel for active ulcerative colitis by Langmead, L., Feakins, R. M., Goldthorpe, S., Holt, H., Tsironi, E., De Silva, A., Jewell, D. P., Rampton, D. S.

“…Summary Background : The herbal preparation, aloe vera, has been claimed to have anti‐inflammatory effects and, despite a lack of evidence of its therapeutic…”
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Review article: herbal treatment in gastrointestinal and liver disease—benefits and dangers by Langmead, L., Rampton, D. S.

“…Herbal medicines are now used by up to 50% of the Western population, in a substantial minority of instances for the treatment or prevention of digestive…”
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Efficacy and tolerability of oral iron therapy in inflammatory bowel disease: a prospective, comparative trial by SILVA, A. D., TSIRONI, E., FEAKINS, R. M., RAMPTON, D. S.

“…Summary Background : In patients with inflammatory bowel disease, oral iron is anecdotally reported to be less effective and less well tolerated than in those…”
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Application of the WHO fracture risk assessment tool (FRAX) to predict need for DEXA scanning and treatment in patients with inflammatory bowel disease at risk of osteoporosis by Goodhand, J. R., Kamperidis, N., Nguyen, H., Wahed, M., Rampton, D. S.

“…Aliment Pharmacol Ther 2011; 33: 551–558 Summary Background  Although patients with inflammatory bowel disease (IBD) are at increased risk of osteoporosis, low…”
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Preventing TB in patients with Crohn’s disease needing infliximab or other anti-TNF therapy by Rampton, D S

“…Recommendations from several sources, including the European Agency for Evaluation of Medicinal Products (EMEA) and the National Institute for Clinical…”
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The phenotype and course of inflammatory bowel disease in UK patients of Bangladeshi descent by Goodhand, J. R., Kamperidis, N., Joshi, N. M., Wahed, M., Koodun, Y., Cantor, E. J., Croft, N. M., Langmead, F. L., Lindsay, J. O., Rampton, D. S.

“…Summary Background We have tested the hypotheses that compared with local white Caucasians, UK‐resident patients of Bangladeshi descent develop inflammatory…”
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Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis by Millar, A D, Rampton, D S, Chander, C L, Claxson, A W, Blades, S, Coumbe, A, Panetta, J, Morris, C J, Blake, D R

“…BACKGROUND: Reactive oxygen species may mediate tissue injury in inflammatory bowel disease. Aminosalicylates have antioxidant activity and the antioxidants,…”
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Antioxidant effects of herbal therapies used by patients with inflammatory bowel disease: an in vitro study by Langmead, L., Dawson, C., Hawkins, C., Banna, N., Loo, S., Rampton, D. S.

“…Background: Herbal remedies used by patients for treatment of inflammatory bowel disease include slippery elm, fenugreek, devil’s claw, Mexican yam, tormentil…”
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Molecular characterization of the bacteria adherent to human colorectal mucosa by Green, G.L., Brostoff, J., Hudspith, B., Michael, M., Mylonaki, M., Rayment, N., Staines, N., Sanderson, J., Rampton, D.S., Bruce, K.D.

“…Aims:  To study large intestinal mucosal bacterial communities by Denaturing Gradient Gel Electrophoresis (DGGE) profiling and sequencing of 16S rRNA gene…”
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Factors Associated With Nonadherence to Thiopurines in Adolescent and Adult Patients With Inflammatory Bowel Disease by Kamperidis, N., Goodhand, J.R., Chowdhury, F.A., Koodun, Y., Direzke, N.C., Naik, S., Sanderson, I.R., Croft, N.M., Langmead, F.L., Irving, P.M., Rampton, D.S., Lindsay, J.O.

“…ABSTRACT Objectives: We hypothesised that nonadherence to thiopurines is more common in adolescents than in adults with inflammatory bowel disease. Methods: We…”
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Do Children With IBD Really Respond Better Than Adults to Thiopurines? by Goodhand, JR, Tshuma, N, Rao, A, Kotta, S, Wahed, M, Croft, NM, Sanderson, IR, Epstein, J, Rampton, DS

“…ABSTRACT Background and Objectives: Children and adolescents with inflammatory bowel disease (IBD) have more extensive and severe disease than adults. Despite…”
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Evaluation of new therapies for inflammatory bowel disease by Carty, E., Rampton, D. S.

“…The pathophysiology of inflammatory bowel disease (IBD) is gradually being unravelled and new therapies are being developed to target the disturbed biological…”
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Mood disorders in inflammatory bowel disease: Relation to diagnosis, disease activity, perceived stress, and other factors by Goodhand, J.R., Wahed, M., Mawdsley, J.E., Farmer, A.D., Aziz, Q., Rampton, D.S.

“…Background: Anxiety and depression are common in patients with inflammatory bowel disease (IBD); however, the factors associated with mood disorders in…”
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