Search Results - "RAM, Arthur F. J"
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Growing a circular economy with fungal biotechnology: a white paper
Published in Fungal biology and biotechnology (02-04-2020)“…Fungi have the ability to transform organic materials into a rich and diverse set of useful products and provide distinct opportunities for tackling the urgent…”
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Aspergillus as a multi-purpose cell factory: current status and perspectives
Published in Biotechnology letters (01-03-2011)“…Aspergilli have a long history in biotechnology as expression platforms for the production of food ingredients, pharmaceuticals and enzymes. The achievements…”
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Expanding the ku70 toolbox for filamentous fungi: establishment of complementation vectors and recipient strains for advanced gene analyses
Published in Applied microbiology and biotechnology (01-07-2010)“…Mutants with a defective non-homologous-end-joining (NHEJ) pathway have boosted functional genomics in filamentous fungi as they are very efficient recipient…”
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Fungal Gene Expression on Demand: an Inducible, Tunable, and Metabolism-Independent Expression System for Aspergillus niger
Published in Applied and Environmental Microbiology (01-05-2011)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The carbon starvation response of Aspergillus niger during submerged cultivation: insights from the transcriptome and secretome
Published in BMC genomics (08-08-2012)“…Filamentous fungi are confronted with changes and limitations of their carbon source during growth in their natural habitats and during industrial…”
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Genome sequencing of the neotype strain CBS 554.65 reveals the MAT1–2 locus of Aspergillus niger
Published in BMC genomics (21-09-2021)“…Abstract Background Aspergillus niger is a ubiquitous filamentous fungus widely employed as a cell factory thanks to its abilities to produce a wide range of…”
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Enhanced surface colonisation and competition during bacterial adaptation to a fungus
Published in Nature communications (27-05-2024)“…Bacterial-fungal interactions influence microbial community performance of most ecosystems and elicit specific microbial behaviours, including stimulating…”
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Role of Pigmentation in Protecting Aspergillus niger Conidiospores Against Pulsed Light Radiation
Published in Photochemistry and photobiology (01-05-2013)“…The photoprotective potential of fungus pigments was investigated by irradiating conidiospores of three Aspergillus niger strains possessing the same genetic…”
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Protoplast-mediated transformation of Madurella mycetomatis using hygromycin resistance as a selection marker
Published in PLoS neglected tropical diseases (01-04-2024)“…Madurella mycetomatis is the main cause of mycetoma, a chronic granulomatous infection for which currently no adequate therapy is available. To improve…”
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Efficient marker free CRISPR/Cas9 genome editing for functional analysis of gene families in filamentous fungi
Published in Fungal biology and biotechnology (21-09-2019)“…CRISPR/Cas9 mediated genome editing has expedited the way of constructing multiple gene alterations in filamentous fungi, whereas traditional methods are…”
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Functional characterization of Rho GTPases in Aspergillus niger uncovers conserved and diverged roles of Rho proteins within filamentous fungi
Published in Molecular microbiology (01-03-2011)“…Rho GTPases are signalling molecules regulating morphology and multiple cellular functions including metabolism and vesicular trafficking. To understand the…”
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I-SceI-mediated double-strand DNA breaks stimulate efficient gene targeting in the industrial fungus Trichoderma reesei
Published in Applied microbiology and biotechnology (01-12-2015)“…Targeted integration of expression cassettes for enzyme production in industrial microorganisms is desirable especially when enzyme variants are screened for…”
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Velvet domain protein VosA represses the zinc cluster transcription factor SclB regulatory network for Aspergillus nidulans asexual development, oxidative stress response and secondary metabolism
Published in PLoS genetics (25-07-2018)“…The NF-κB-like velvet domain protein VosA (viability of spores) binds to more than 1,500 promoter sequences in the filamentous fungus Aspergillus nidulans…”
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High sorbic acid resistance of Penicillium roqueforti is mediated by the SORBUS gene cluster
Published in PLoS genetics (01-06-2022)“…Penicillium roqueforti is a major food-spoilage fungus known for its high resistance to the food preservative sorbic acid. Here, we demonstrate that the…”
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A set of isogenic auxotrophic strains for constructing multiple gene deletion mutants and parasexual crossings in Aspergillus niger
Published in Archives of microbiology (01-11-2016)“…To construct a set of isogenic auxotrophic strains in Aspergillus niger suited for creating multiple gene deletion mutants and executing parasexual crossings,…”
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Autophagy promotes survival in aging submerged cultures of the filamentous fungus Aspergillus niger
Published in Applied microbiology and biotechnology (01-09-2013)“…Autophagy is a well-conserved catabolic process constitutively active in eukaryotes that is involved in maintaining cellular homeostasis by the targeting of…”
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Competition between homologous chromosomal DNA and exogenous donor DNA to repair CRISPR/Cas9-induced double-strand breaks in Aspergillus niger
Published in Fungal biology and biotechnology (15-10-2024)“…Aspergillus niger is well-known for its high protein secretion capacity and therefore an important cell factory for homologous and heterologous protein…”
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Agrobacterium -mediated transformation of the filamentous fungus Aspergillus awamori
Published in Nature protocols (01-10-2008)“…Many transformation methods have been developed to introduce DNA into filamentous fungi. One of these methods is Agrobacterium -mediated transformation (AMT)…”
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Agrobacterium-mediated transformation as a tool for functional genomics in fungi
Published in Current genetics (01-07-2005)“…In the era of functional genomics, the need for tools to perform large-scale targeted and random mutagenesis is increasing. A potential tool is…”
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Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger
Published in Applied microbiology and biotechnology (01-01-2011)“…Endoplasmic reticulum associated degradation (ERAD) is a conserved mechanism to remove misfolded proteins from the ER by targeting them to the proteasome for…”
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