Search Results - "RALSTON, S. H."

Presentation and management of osteoporosis presenting in association with pregnancy or lactation by Kovacs, C. S., Ralston, S. H.

“…In this review, we summarize our current understanding of the pathophysiology of fragility fractures that occur for the first time during pregnancy and…”
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The Effect of Anti-rheumatic Drugs on the Skeleton by Hauser, B., Raterman, H., Ralston, S. H., Lems, W. F.

“…The therapeutic armamentarium for rheumatoid arthritis has increased substantially over the last 20 years. Historically antirheumatic treatment was started…”
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Polymorphisms in the 5′ flank of COL1A1 gene and osteoporosis: meta-analysis of published studies by Jin, H, Evangelou, E, Ioannidis, J. P. A, Ralston, S. H

“…Summary A meta-analysis of studies was conducted involving 24,511 participants with 7,864 fractures in which polymorphisms in the 5′ flank of COL1A1…”
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Meta-analysis of COL1A1 Sp1 polymorphism in relation to bone mineral density and osteoporotic fracture by Mann, V, Ralston, S.H

“…Genetic factors play an important role in the pathogenesis of osteoporosis and several candidate gene polymorphisms have been implicated in the regulation of…”
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A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis by Lekamwasam, S., Adachi, J. D., Agnusdei, D., Bilezikian, J., Boonen, S., Borgström, F., Cooper, C., Diez Perez, A., Eastell, R., Hofbauer, L. C., Kanis, J. A., Langdahl, B. L., Lesnyak, O., Lorenc, R., McCloskey, E., Messina, O. D., Napoli, N., Obermayer-Pietsch, B., Ralston, S. H., Sambrook, P. N., Silverman, S., Sosa, M., Stepan, J., Suppan, G., Wahl, D. A., Compston, J. E.

“…Summary This paper provides a framework for the development of national guidelines for the management of glucocorticoid-induced osteoporosis in men and women…”
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Hydrogen sulphide‐releasing diclofenac derivatives inhibit breast cancer‐induced osteoclastogenesis in vitro and prevent osteolysis ex vivo by Frantzias, J, Logan, JG, Mollat, P, Sparatore, A, Del Soldato, P, Ralston, SH, Idris, AI

“…BACKGROUND AND PURPOSE Hydrogen sulphide (H2S) and prostaglandins are both involved in inflammation, cancer and bone turnover, and non‐steroidal…”
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Paget's disease of bone by Tan, A, Ralston, S H

“…Paget's disease of bone is a common disorder characterized by increased but disorganized bone remodelling. Some patients are asymptomatic but others present…”
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Risk of severe COVID-19 in patients with inflammatory rheumatic diseases treated with immunosuppressive therapy in Scotland by McKeigue, P M, Porter, D, Hollick, R J, Ralston, S H, McAllister, D A, Colhoun, H M

“…To investigate the association of severe coronavirus disease 2019 (COVID-19) in patients with inflammatory rheumatic diseases (IRDs) treated with…”
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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study by Panoutsopoulou, K, Southam, L, Elliott, K S, Wrayner, N, Zhai, G, Beazley, C, Thorleifsson, G, Arden, N K, Carr, A, Chapman, K, Deloukas, P, Doherty, M, McCaskie, A, Ollier, W E R, Ralston, S H, Spector, T D, Valdes, A M, Wallis, G A, Wilkinson, J M, Arden, E, Battley, K, Blackburn, H, Blanco, F J, Bumpstead, S, Cupples, L A, Day-Williams, A G, Dixon, K, Doherty, S A, Esko, T, Evangelou, E, Felson, D, Gomez-Reino, J J, Gonzalez, A, Gordon, A, Gwilliam, R, Halldorsson, B V, Hauksson, V B, Hofman, A, Hunt, S E, Ioannidis, J P A, Ingvarsson, T, Jonsdottir, I, Jonsson, H, Keen, R, Kerkhof, H J M, Kloppenburg, M G, Koller, N, Lakenberg, N, Lane, N E, Lee, A T, Metspalu, A, Meulenbelt, I, Nevitt, M C, O'Neill, F, Parimi, N, Potter, S C, Rego-Perez, I, Riancho, J A, Sherburn, K, Slagboom, P E, Stefansson, K, Styrkarsdottir, U, Sumillera, M, Swift, D, Thorsteinsdottir, U, Tsezou, A, Uitterlinden, A G, van Meurs, J B J, Watkins, B, Wheeler, M, Mitchell, S, Zhu, Y, Zmuda, J M, Zeggini, E, Loughlin, J

“…The genetic aetiology of osteoarthritis has not yet been elucidated. To enable a well-powered genome-wide association study (GWAS) for osteoarthritis, the…”
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Management of Paget's disease of bone by Langston, A. L., Ralston, S. H.

“…Paget's disease of bone is a common condition with a strong genetic component, characterized by focal increases in bone turnover, affecting one or more bones…”
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Guidelines on the management of Paget’s disease of bone by Selby, P.L, Davie, M.W.J, Ralston, S.H, Stone, M.D

“…Article outline: introduction, background, diagnosis, indications for treatment, monitoring treatment…”
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Role of genetic factors in the pathogenesis of osteoporosis by Stewart, TL, Ralston, SH

“…Osteoporosis is a common disease with a strong genetic component characterised by low bone mass, microarchitectural deterioration of bone tissue and an…”
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The relationship of fall-related fractures to social deprivation by Court-Brown, C. M., Aitken, S. A., Ralston, S. H., McQueen, M. M.

“…Summary The relationship between fall-related fractures and social deprivation was studied in 3,843 patients. The incidence of fractures correlated with…”
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Diagnosis and management of primary hyperparathyroidism in Europe by LANGDAHL, B. L, RALSTON, S. H

“…There is continued debate as to the optimal strategy for diagnosis and management of primary hyperparathyroidism (PHPT). To compare the strategies used for the…”
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Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I α 1 gene by Grant, Struan F. A, Reid, David M, Blake, Glen, Herd, Ruth, Fogelman, Ignac, Ralston, Stuart H

“…Osteoporosis is a common disease with a strong genetic component, characterized by reduced bone mass and increased fracture risk. Current evidence suggests…”
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A UK Consensus Group on management of glucocorticoid‐induced osteoporosis: an update by Eastell, R., Reid, D. M., Compston, J., Cooper, C., Fogelman, I., Francis, R. M., Hosking, D. J., Purdie, D. W., Ralston, S. H., Reeve, J., Russell, R. G. G., Stevenson, J. C., Torgerson, D. J.

“… Eastell R, Reid DM, Compston J, Cooper C, Fogelman I, Francis RM, Hosking DJ, Purdie DW, Ralston SH, Reeve J, Russell RGG, Stevenson JC, Torgerson DJ…”
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Clinical Risk Factors for Osteoporosis in Ireland and the UK: A Comparison of FRAX and QFractureScores by Cummins, N. M., Poku, E. K., Towler, M. R., O’Driscoll, O. M., Ralston, S. H.

“…Recently two algorithms have become available to estimate the 10-year probability of fracture in patients suspected to have osteoporosis on the basis of…”
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Association of the Pro12Ala and C1431t variants of PPARG and their haplotypes with susceptibility to Type 2 diabetes by DONEY, A. S. F, FISCHER, B, CECIL, J. E, BOYLAN, K, MCGUIGAN, F. E, RALSTON, S. H, MORRIS, A. D, PALMER, C. N. A

“…The Pro12Ala polymorphism of peroxisome proliferator-activated receptor (PPAR)gamma has been consistently associated with Type 2 diabetes. The rare Ala12…”
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Diagnosis and Management of Osteoporosis During COVID-19: Systematic Review and Practical Guidance by Hampson, G., Stone, M., Lindsay, J. R., Crowley, R. K., Ralston, S. H.

“…It is acknowledged that the COVID-19 pandemic has caused profound disruption to the delivery of healthcare services globally. This has affected the management…”
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Clinical determinants of quality of life in Paget's disease of bone by Langston, A L, Campbell, M K, Fraser, W D, Maclennan, G, Selby, P, Ralston, S H

“…Paget's disease of bone (PDB) can adversely affect quality of life, but relatively little is known about the clinical predictors of reduced quality of life in…”
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