Search Results - "RAKOWITZ, D"

N-substituted tetrahydro-2,4-dioxoquinazolin-1-yl acetic acids as aldose reductase inhibitors by Rakowitz, D, Gmeiner, A, Matuszczak, B

“…Novel N-substituted tetrahydro-2,4-dioxoquinazolin-1-yl acetic acids characterized by formal replacement of the substituted benzyl moiety by cyclohexylmethyl…”
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Thienocinnolinone alkanoic acid derivatives as aldose reductase inhibitors by Pau, A, Asproni, B, Murineddu, G, Boatto, G, Grella, G E, Rakowitz, D, Costantino, L, Pinna, G A

“…A new series of 8-halogen-4,4a,5,6-tetrahydrothieno[2,3-h]cinnolinone-N2-alkanoic acids was prepared and tested for aldose reductase (ALR2) inhibitory…”
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Structure–activity relationships and molecular modelling of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors by Maccari, Rosanna, Ottanà, Rosaria, Curinga, Carmela, Vigorita, Maria Gabriella, Rakowitz, Dietmar, Steindl, Theodora, Langer, Thierry

“…[Display omitted] The structure–activity relationships (SARs) of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors (ARIs) were extended…”
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In vitro aldose reductase inhibitory activity of 5-benzyl-2,4-thiazolidinediones by Rakowitz, Dietmar, Maccari, Rosanna, Ottanà, Rosaria, Vigorita, Maria Gabriella

“…Several 5-benzyl-2,4-thiazolidinediones ( 5– 7) were synthesised and tested as in vitro aldose reductase (ALR2) inhibitors. Most of them, particularly…”
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Synthesis of novel phenylacetic acid derivatives with halogenated benzyl subunit and evaluation as aldose reductase inhibitors by Rakowitz, Dietmar, Gmeiner, Andreas, Schröder, Nicole, Matuszczak, Barbara

“…In the course of our ongoing studies several substituted benzyloxyphenylacetic acids were prepared. Comparison of their aldose reductase inhibition with the…”
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Synthesis of Novel Benzoic Acid Derivatives with Benzothiazolyl Subunit and Evaluation as Aldose Reductase Inhibitors by Rakowitz, Dietmar, Hennig, Barbara, Nagano, Marietta, Steger, Stefan, Costantino, Luca, Matuszczak, Barbara

“…Several methyl benzothiazolyloxybenzoates, S‐isosters, and the corresponding benzoic acids were synthesized and tested as aldose reductase inhibitors (ARIs)…”
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Diazine-derived guanidines, isothioureas, and isoureas: Synthesis and attempts of configurational assignment by Heinisch, Gottfried, Matuszczak, Barbara, Rakowitz, Dietmar, Mereiter, Kurt

“…The utility of diazinyl substituted carbodiimides (1a‐c) for the synthesis of novel guanidines (2), isothioureas (3), and isoureas (4) is shown. Attempts to…”
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EQUILIBRIA IN THE FIBRINOGEN—FIBRIN CONVERSION1 by Laskowski, M, Rakowitz, D. H, Scheraga, H. A

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On the prodrug potential of novel aldose reductase inhibitors with diphenylmethyleneaminooxycarboxylic acid structure by Rakowitz, Dietmar, Matuszczak, Barbara, Gritsch, Stefan, Hofbauer, Peter, Krassnigg, Andreas, Costantino, Luca

“…Diphenylmethyleneaminooxycarboxylic acids were found to represent novel type inhibitors of the enzyme aldose reductase. Ester derivatives of the most active…”
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Pyridazines 93. an unexpected reaction behaviour of 3-aminopyridazine towards 2-methylphenylisocyanate by Heinisch, Gottfried, Hetzenauer, Alfred, Matuszczak, Barbara, Rakowitz, Dietmar, Mereiter, Kurt

“…Reaction of 3‐aminopyridazine (1) with 2‐mefhylphenylisocyante (4) affords not only the desired urea derivative (5) but also an unexpected side‐product (6),…”
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Synthesis of N-aryl-N'-heteroaryl-substituted urea and thiourea derivatives and evaluation of their anticonvulsant activity by Heinisch, G, Matuszczak, B, Rakowitz, D, Tantisira, B

“…Starting from amino(di)azines and 2-chloro-6-methyliso(thio)cyanate a series of aryl-substituted urea and thiourea derivatives was prepared and screened as…”
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Complete Assignment of the 13C NMR Spectra of Diazinyl-Substituted Ureas and Thioureas by HEINISCH, G., LUKAVSKY, P., MATUSZCZAK, B., RAKOWITZ, D.

“…The total assignment of the 13C NMR spectra of novel diazine derived ureas and thioureas is reported. © 1997 by John Wiley & Sons, Ltd…”
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Complete Assignment of the13C NMR Spectra of Diazinyl-Substituted Ureas and Thioureas by HEINISCH, G., LUKAVSKY, P., MATUSZCZAK, B., RAKOWITZ, D.

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A series of diarylsubstituted oximes as potential substrate for new aldose reductase inhibitors by Rakowitz, Dietmar, Heinisch, Gottfried, Lukavsky, Peter, Kiendler, Sigrid, Trenkwalder, Cornelia, Barlocco, Daniela, Rastelli, Giulio, Costantino, Luca

“…In the course of our research aimed at the discovery of new compounds acting as aldose reductase inhibitors, we tested a series of some (E)‐ and…”
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Diazine-substituted tert-butylureas and tert-butylthioureas and a convenient access to the related carbodiimides by Heinisch, Gottfried, Matuszczak, Barbara, Pürstinger, Gerhard, Rakowitz, Dietmar

“…An efficient procedure for the preparation of diazine‐substituted urea and thiourea derivatives 3a‐c, 5a‐c is proposed. On attempts to prepare the related…”
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Insight into novel cyclization reactions using acetic anhydride in the presence of 4-dimethylaminopyridine by AICHNER, J, EGG, H, GAPP, D, HALLER, S, RAKOWITZ, D, RAMSPACHER, U

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EQUILIBRIA IN THE FIBRINOGEN—FIBRIN CONVERSION 1 by Laskowski, M., Rakowitz, D. H., Scheraga, H. A.

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