Search Results - "RAKIĆ, LJUBIŠA M."

The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: Therapeutic interventions and a comparison with the monoamine depleter, reserpine by Buznikov, Gennady A, Nikitina, Lyudmila A, Rakić, Ljubiša M, Milošević, Ivan, Bezuglov, Vladimir V, Lauder, Jean M, Slotkin, Theodore A

“…Abstract Lower organisms show promise for the screening of neurotoxicants that might target mammalian brain development. Sea urchins use neurotransmitters as…”
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Sea urchin embryonic development provides a model for evaluating therapies against β-amyloid toxicity by Buznikov, Gennady A, Nikitina, Lyudmila A, Bezuglov, Vladimir V, Milošević, Ivan, Lazarević, Lidija, Rogač, Ljubica, Ruzdijić, Sabera, Slotkin, Theodore A, Rakić, Ljubiša M

“…Abstract Accumulation of β-amyloid protein is an Alzheimer's disease hallmark but also may be mechanistically involved in neurodegeneration. One of its…”
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Amyloid precursor protein 96–110 and β-amyloid 1–42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids by Buznikov, Gennady A, Nikitina, Lyudmila A, Seidler, Frederic J, Slotkin, Theodore A, Bezuglov, Vladimir V, Milošević, Ivan, Lazarević, Lidija, Rogač, Ljubica, Ruzdijić, Sabera, Rakić, Ljubiša M

“…Abstract Amyloid precursor protein (APP) is overexpressed in the developing brain and portions of its extracellular domain, especially amino acid residues…”
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The characteristics of basolateral nucleoside transport in the perfused sheep choroid plexus and the effect of nitric oxide inhibition on these processes by Redžić, Zoran B, Segal, Malcolm B, Marković, Ivanka D, Gašić, Jovana M, Vidović, Vanesa, Rakić, Ljubiša M

“…The single pass paired dilution technique was used to measure the uptake of nucleosides across the basolateral face of the isolated in situ perfused sheep…”
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The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep by Redzic, Zoran B, Gasic, Jovana M, Segal, Malcolm B, Markovic, Ivanka D, Isakovic, Aleksandra J, Rakic, Miodrag Lj, Thomas, Sarah A, Rakic, Ljubisa M

“…The uptake of principal salvageable nucleobase hypoxanthine was investigated across the basolateral membrane of the sheep choroid plexus (CP) perfused in situ…”
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Endogenous Nucleosides in the Guinea-pig Eye: Analysis of Transport and Metabolites by REDŽIĆ, ZORAN B., MARKOVIĆ, IVANKA D., VIDOVIĆ, VANESA P., VRANIĆ, VALENTINA P., GAŠIĆ, JOVANA M., DURIČIĆ, BOGDAN M., POKRAJAC, MILENA, DORDEVIĆ, JELICA B., SEGAL, MALCOLM B., RAKIĆ, LJUBIŠA M.

“…This study investigates the transport of endogenous nucleosides and deoxynucleosides from the capillaries of the eye into the aqueous humour and the lens using…”
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The characteristics of nucleobase transport and metabolism by the perfused sheep choroid plexus by Redzic, Zoran B, Segal, Malcolm B, Gasic, Jovana M, Markovic, Ivanka D, Vojvodic, Vanesa P, Isakovic, Aleksandra, Thomas, Sarah A, Rakic, Ljubisa M

“…The uptake of nucleobases was investigated across the basolateral membrane of the sheep choroid plexus perfused in situ. The maximal uptake ( U max) for…”
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The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells by DACEVIC, Mirjana P, TASIC, Jelena S, PEJANOVIC, Vjera M, SEGAL, Malcolm B, UGLJESIC-KILIBARDA, Dragana D, ISAKOVIC, Aleksandra J, BEGLEY, David J, RAKIC, Ljubisa M, REDZIC, Zoran B

“…The aim of this study was to analyse the uptake of the synthetic nucleoside tiazofurin and glucoso-linker-tiazofurin conjugate (GLTC) into rat C6 glioma cells…”
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Amyloid precursor protein 96-110 and β-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids by BUZNIKOV, Gennady A, NIKITINA, Lyudmila A, SEIDLER, Frederic J, SLOTKIN, Theodore A, BEZUGLOV, Vladimir V, MILOSEVIC, Ivan, LAZAREVIC, Lidija, ROGAC, Ljubica, RUZDIJIC, Sabera, RAKIC, Ljubisa M

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The kinetics of hypoxanthine efflux from the rat brain by Redzic, Zoran B., Isakovic, Aleksandra, Segal, Malcolm B., Thomas, Sarah A., Rakic, Ljubisa M.

“…The brain efflux of radiolabelled hypoxanthine in the rat was rapid in the first minute after injection [ K eff(i)=0.21±0.06 min −1], which was saturable with…”
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Chronic amphetamine intoxication and the blood-brain barrier permeability to inert polar molecules studied in the vascularly perfused guinea pig brain by Rakic, L M, Zlokovic, B V, Davson, H, Segal, M B, Begley, D J, Lipovac, M N, Mitrovic, D M

“…The brain vascular perfusion method, with a multiple-time brain uptake analysis, has been employed to study the effects of chronic amphetamine intoxication on…”
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Kinetics and sodium independence of [3H]-tiazofurin blood to brain transport in the guinea pig by Redzic, Z B, Markovic, I D, Jovanovic, S S, Gasic, J M, Mitrovic, D M, Zlokovics, B V, Rakic, L M

“…Tiazofurin is a nucleoside analog with potent antitumor activity. The objective of this study was to define the kinetic parameters of tiazofurin transport from…”
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