Search Results - "RAJPAR, M"

Riverine forest as a significant habitat to harbor a wide range of bird species by Rajpar, M N, Rajpar, A H, Zakaria, M

“…Riverine forests are unique and highly significant ecosystems that are globally important for diverse and threatened avian species. Apart from being a cradle…”
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Increased classical endoplasmic reticulum stress is sufficient to reduce chondrocyte proliferation rate in the growth plate and decrease bone growth by Kung, Louise H W, Rajpar, M Helen, Preziosi, Richard, Briggs, Michael D, Boot-Handford, Raymond P

“…Mutations in genes encoding cartilage oligomeric matrix protein and matrilin-3 cause a spectrum of chondrodysplasias called multiple epiphyseal dysplasia (MED)…”
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Targeted induction of endoplasmic reticulum stress induces cartilage pathology by Rajpar, M Helen, McDermott, Ben, Kung, Louise, Eardley, Rachel, Knowles, Lynette, Heeran, Mel, Thornton, David J, Wilson, Richard, Bateman, John F, Poulsom, Richard, Arvan, Peter, Kadler, Karl E, Briggs, Michael D, Boot-Handford, Raymond P

“…Pathologies caused by mutations in extracellular matrix proteins are generally considered to result from the synthesis of extracellular matrices that are…”
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Mutation of the gene encoding the enamel-specific protein, enamelin, causes autosomal-dominant amelogenesis imperfecta by RAJPAR, M. Helen, HARLEY, Kathryn, LAING, Chris, DAVIES, Robin M, DIXON, Michael J

“…Amelogenesis imperfecta (AI) is a group of inherited defects of dental enamel formation that shows both clinical and genetic heterogeneity. To date, mutations…”
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Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy by Cameron, Trevor L, Bell, Katrina M, Tatarczuch, Liliana, Mackie, Eleanor J, Rajpar, M Helen, McDermott, Ben T, Boot-Handford, Raymond P, Bateman, John F

“…Metaphyseal chondrodysplasia, Schmid type (MCDS) is characterized by mild short stature and growth plate hypertrophic zone expansion, and caused by collagen X…”
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Mutation of the signal peptide region of the bicistronic gene DSPP affects translocation to the endoplasmic reticulum and results in defective dentine biomineralization by Rajpar, M. Helen, Koch, Martin J., Davies, Robin M., Mellody, Kieran T., Kielty, Cay M., Dixon, Michael J.

“…Dentine dysplasia type II is an autosomal dominant disorder in which mineralization of the dentine of the primary teeth is abnormal. On the basis of the…”
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Vegetation–edaphic correlation and importance value index in himalayan ‘ecotone’ temperate conifer forest using the multivariate technique by Ali, F., Zeb, M., Amin, M., Rajpar, M.N., Hidayat, S., Khan, W.R.

“…Himalayan ‘Ecotone’ temperate conifer forest is the cradle of life for human survival and wildlife existence. In spite of the importance of these areas, they…”
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Germline E-cadherin Gene (CDH1) Mutations Predispose to Familial Gastric Cancer and Colorectal Cancer by Richards, Frances M., McKee, Shane A., Rajpar, M. Helen, Cole, Trevor R. P., Evans, D. Gareth R., Jankowski, Janusz A., McKeown, Carole, Sanders, D. Scott A., Maher, Eamonn R.

“…Inherited mutations in the E-cadherin gene (CDH1) were described recently in three Maori kindreds with familial gastric cancer. Familial gastric cancer is…”
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An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia by Nundlall, Seema, Rajpar, M. Helen, Bell, Peter A., Clowes, Christopher, Zeeff, Leo A. H., Gardner, Benjamin, Thornton, David J., Boot-Handford, Raymond P., Briggs, Michael D.

“…Multiple epiphyseal dysplasia (MED) can result from mutations in matrilin-3, a structural protein of the cartilage extracellular matrix. We have previously…”
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A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth by Gualeni, Benedetta, Rajpar, M Helen, Kellogg, Aaron, Bell, Peter A, Arvan, Peter, Boot-Handford, Raymond P, Briggs, Michael D

“…Disease mechanisms leading to different forms of chondrodysplasia include extracellular matrix (ECM) alterations and intracellular stress resulting in abnormal…”
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Hypertrophic Chondrocytes Have a Limited Capacity to Cope with Increases in Endoplasmic Reticulum Stress without Triggering the Unfolded Protein Response by Kung, Louise H. W., Rajpar, M. Helen, Briggs, Michael D., Boot-Handford, Raymond P.

“…Mutations causing metaphyseal chondrodysplasia type Schmid (MCDS) (e.g., Col10a1p.N617K) induce the pathology by a mechanism involving increased endoplasmic…”
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Germline mutation analysis of the transforming growth factor β receptor type II (TGFBR2) and E-cadherin (CDH1) genes in early onset and familial colorectal cancer by VERMA, LOVEENA, PORTER, TIMOTHY R, RICHARDS, FRANCES M, RAJPAR, M HELEN, EVANS, D GARETH R, MACDONALD, FIONA, MAHER, EAMONN R

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One-year outcome in early aneurysm surgery : a 14 years experience by HERNESNIEMI, J, VAPALAHTI, M, NISKANEN, M, TAPANINAHO, A, KARI, A, LUUKKONEN, M, PURANEN, M, SAARI, T, RAJPAR, M

“…In a consecutive series of 1150 patients with cerebral aneurysms diagnosed in our department by angiography or autopsy between the years 1977-1990, 1007…”
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Targeted induction of endoplasmic reticulum stress induces cartilage pathology by Rajpar, M. Helen, McDermott, Ben, Kung, Louise, Eardley, Rachel, Knowles, Lynette, Heeran, Mel, Thornton, David J, Wilson, Richard, Bateman, John F, Poulsom, Richard, Arvan, Peter, Kadler, Karl E, Briggs, Michael D, Boot-Handford, Raymond P

“…Pathologies caused by mutations in extracellular matrix proteins are generally considered to result from the synthesis of extracellular matrices that are…”
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Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology: e1000691 by Rajpar, M Helen, McDermott, Ben, Kung, Louise, Eardley, Rachel, Knowles, Lynette, Heeran, Mel, Thornton, David J, Wilson, Richard, Bateman, John F, Poulsom, Richard, Arvan, Peter, Kadler, Karl E, Briggs, Michael D, Boot-Handford, Raymond P

“…Pathologies caused by mutations in extracellular matrix proteins are generally considered to result from the synthesis of extracellular matrices that are…”
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Diazepam as an adjunct in propanidid anaesthesia for abortion by Mattila, M A, Rajpar, M, Pystynen, P

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Germline mutation analysis of the transforming growth factor [beta] receptor type II (TGFBR2) and E-cadherin (CDH1) genes in early onset and familial colorectal cancer by VERMA, LOVEENA, PORTER, TIMOTHY R, RICHARDS, FRANCES M, RAJPAR, M HELEN, EVANS, D GARETH R, MACDONALD, FIONA, MAHER, EAMONN R

“…2 4-6 Candidate gene approaches to identify further genes for early onset and familial CRC have been largely unsuccessful. [...]mutation analysis of β-catenin…”
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Laboratory investigation of cutaneous leishmaniasis in Karachi by Rajpar, G M, Khan, M A, Hafiz, A

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Surgical treatment of arteriovenous malformations of the brain by Hernesniemi, J, Keränen, T, Puranen, M, Rajpar, M

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