Search Results - "RAJA, Srinivasa"

Treatment of acute postoperative pain by Wu, Christopher L, Prof, Raja, Srinivasa N, Prof

“…Summary Although postoperative pain remains incompletely controlled in some settings, increased understanding of its mechanisms and the development of several…”
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The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises by Raja, Srinivasa N., Carr, Daniel B., Cohen, Milton, Finnerup, Nanna B., Flor, Herta, Gibson, Stephen, Keefe, Francis J., Mogil, Jeffrey S., Ringkamp, Matthias, Sluka, Kathleen A., Song, Xue-Jun, Stevens, Bonnie, Sullivan, Mark D., Tutelman, Perri R., Ushida, Takahiro, Vader, Kyle

“…The current International Association for the Study of Pain (IASP) definition of pain as "An unpleasant sensory and emotional experience associated with actual…”
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John J. Bonica Award Lecture: Peripheral neuronal hyperexcitability: the “low-hanging” target for safe therapeutic strategies in neuropathic pain by Raja, Srinivasa N., Ringkamp, Matthias, Guan, Yun, Campbell, James N.

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Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis by Finnerup, Nanna B, MD, Attal, Nadine, Prof, Haroutounian, Simon, PhD, McNicol, Ewan, MS, Baron, Ralf, Prof, Dworkin, Robert H, Prof, Gilron, Ian, Prof, Haanpää, Maija, MD, Hansson, Per, Prof, Jensen, Troels S, Prof, Kamerman, Peter R, PhD, Lund, Karen, MD, Moore, Andrew, Prof, Raja, Srinivasa N, Prof, Rice, Andrew S C, Prof, Rowbotham, Michael, Prof, Sena, Emily, PhD, Siddall, Philip, Prof, Smith, Blair H, Prof, Wallace, Mark, Prof

“…Summary Background New drug treatments, clinical trials, and standards of quality for assessment of evidence justify an update of evidence-based…”
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Targeting sensory neuron GPCRs for peripheral neuropathic pain by Uniyal, Ankit, Tiwari, Vinod, Tsukamoto, Takashi, Dong, Xinzhong, Guan, Yun, Raja, Srinivasa N

“…Despite the high prevalence of peripheral neuropathic pain (NP) conditions and significant progress in understanding its underlying mechanisms, the management…”
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Central Sensitization, N-methyl-D-aspartate Receptors, and Human Experimental Pain Models: Bridging the Gap between Target Discovery and Drug Development by Raja, Srinivasa N, Sivanesan, Eellan, Guan, Yun

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Spinal Cord Stimulation: Clinical Efficacy and Potential Mechanisms by Sdrulla, Andrei D., Guan, Yun, Raja, Srinivasa N.

“…Spinal cord stimulation (SCS) is a minimally invasive therapy used for the treatment of chronic neuropathic pain. SCS is a safe and effective alternative to…”
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Neuropathic pain: an updated grading system for research and clinical practice by Finnerup, Nanna B., Haroutounian, Simon, Kamerman, Peter, Baron, Ralf, Bennett, David L.H., Bouhassira, Didier, Cruccu, Giorgio, Freeman, Roy, Hansson, Per, Nurmikko, Turo, Raja, Srinivasa N., Rice, Andrew S.C., Serra, Jordi, Smith, Blair H., Treede, Rolf-Detlef, Jensen, Troels S.

“…The redefinition of neuropathic pain as "pain arising as a direct consequence of a lesion or disease affecting the somatosensory system," which was suggested…”
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Pathogenesis, diagnosis, and treatment of lumbar zygapophysial (facet) joint pain by COHEN, Steven P, RAJA, Srinivasa N

“…Lumbar zygapophysial joint arthropathy is a challenging condition affecting up to 15% of patients with chronic low back pain. The onset of lumbar facet joint…”
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Modulating the delicate glial―neuronal interactions in neuropathic pain: Promises and potential caveats by TIWARI, Vinod, YUN GUAN, RAJA, Srinivasa N

“…During neuropathic pain, glial cells (mainly astrocytes and microglia) become activated and initiate a series of signaling cascades that modulate pain…”
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TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception by Park, Una, Vastani, Nisha, Guan, Yun, Raja, Srinivasa N, Koltzenburg, Martin, Caterina, Michael J

“…TRP vanilloid 2 (TRPV2) is a nonselective cation channel expressed prominently in medium- to large-diameter sensory neurons that can be activated by extreme…”
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The IASP classification of chronic pain for ICD-11: chronic neuropathic pain by Scholz, Joachim, Finnerup, Nanna B., Attal, Nadine, Aziz, Qasim, Baron, Ralf, Bennett, Michael I., Benoliel, Rafael, Cohen, Milton, Cruccu, Giorgio, Davis, Karen D., Evers, Stefan, First, Michael, Giamberardino, Maria Adele, Hansson, Per, Kaasa, Stein, Korwisi, Beatrice, Kosek, Eva, Lavand'homme, Patricia, Nicholas, Michael, Nurmikko, Turo, Perrot, Serge, Raja, Srinivasa N., Rice, Andrew S.C., Rowbotham, Michael C., Schug, Stephan, Simpson, David M., Smith, Blair H., Svensson, Peter, Vlaeyen, Johan W.S., Wang, Shuu-Jiun, Barke, Antonia, Rief, Winfried, Treede, Rolf-Detlef

“…The upcoming 11th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD) of the World Health Organization (WHO)…”
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Interventional management of neuropathic pain: NeuPSIG recommendations by Dworkin, Robert H., O’Connor, Alec B., Kent, Joel, Mackey, Sean C., Raja, Srinivasa N., Stacey, Brett R., Levy, Robert M., Backonja, Miroslav, Baron, Ralf, Harke, Henning, Loeser, John D., Treede, Rolf-Detlef, Turk, Dennis C., Wells, Christopher D.

“…Neuropathic pain (NP) is often refractory to pharmacologic and noninterventional treatment. On behalf of the International Association for the Study of Pain…”
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Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors by Edwards, Robert H, Seal, Rebecca P, Wang, Xidao, Guan, Yun, Raja, Srinivasa N, Woodbury, C. Jeffery, Basbaum, Allan I

“…Mechanical pain contributes to the morbidity associated with inflammation and trauma, but primary sensory neurons that convey the sensation of acute and…”
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Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update by Dworkin, Robert H., PhD, O'Connor, Alec B., MD, Audette, Joseph, MD, Baron, Ralf, Dr Med, Gourlay, Geoffrey K., PhD, Haanpää, Maija L., MD, PhD, Kent, Joel L., MD, Krane, Elliot J., MD, LeBel, Alyssa A., MD, Levy, Robert M., MD, PhD, Mackey, Sean C., MD, PhD, Mayer, John, DC, PhD, Miaskowski, Christine, RN, PhD, Raja, Srinivasa N., MD, Rice, Andrew S.C., MB, MD, FRCA, Schmader, Kenneth E., MD, Stacey, Brett, MD, Stanos, Steven, DO, Treede, Rolf-Detlef, Dr Med, Turk, Dennis C., PhD, Walco, Gary A., PhD, Wells, Christopher D., MB

“…The Neuropathic Pain Special Interest Group of the International Association for the Study of Pain recently sponsored the development of evidence-based…”
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Artificial intelligence and pain management: cautiously optimistic by Srinivasan, Bhargav, Venkataraman, Archana, Raja, Srinivasa N

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Activation of µ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents by Tiwari, Vinod, He, Shao-Qiu, Huang, Qian, Liang, Lingli, Yang, Fei, Chen, Zhiyong, Tiwari, Vineeta, Fujita, Wakako, Devi, Lakshmi A., Dong, Xinzhong, Guan, Yun, Raja, Srinivasa N.

“…Several reports support the idea that µ- and δ-opioid receptors (ORs) may exist as heterodimers in brain regions involved in pain signaling. The unique…”
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Pharmacologic therapies for neuropathic pain: an assessment of reporting biases in randomized controlled trials by Schwartz, Stefani M., Barpujari, Awinita, Finnerup, Nanna Brix, Raja, Srinivasa N.

“…Several different reporting biases cited in scientific literature have raised concerns about the overestimation of effects and the subsequent potential impact…”
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Neuropathic pain by Colloca, Luana, Ludman, Taylor, Bouhassira, Didier, Baron, Ralf, Dickenson, Anthony H., Yarnitsky, David, Freeman, Roy, Truini, Andrea, Attal, Nadine, Finnerup, Nanna B., Eccleston, Christopher, Kalso, Eija, Bennett, David L., Dworkin, Robert H., Raja, Srinivasa N.

“…Neuropathic pain is caused by a lesion or disease of the somatosensory system, including peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and…”
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Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future by Sivanesan, Eellan, Maher, Dermot P, Raja, Srinivasa N, Linderoth, Bengt, Guan, Yun

“…The field of spinal cord stimulation is expanding rapidly, with new waveform paradigms asserting supraspinal sites of action. The scope of treatment…”
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