Search Results - "RAIT, VLADIMIR"

Modeling formalin fixation and antigen retrieval with bovine pancreatic ribonuclease A: I—Structural and functional alterations by Rait, Vladimir K, O'Leary, Timothy J, Mason, Jeffrey T

“…Understanding the chemistry of protein modification by formaldehyde is central to developing improved methods to recover proteins from formalin-fixed…”
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Modeling formalin fixation and antigen retrieval with bovine pancreatic RNase A II. Interrelationship of cross-linking, immunoreactivity, and heat treatment by Rait, Vladimir K, Xu, Lixin, O'Leary, Timothy J, Mason, Jeffrey T

“…In this study, gel electrophoresis and capture enzyme-linked immunosorbent assay were used to assess the effect of formaldehyde treatment on the structural and…”
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Conversions of Formaldehyde-modified 2'-Deoxyadenosine 5'-Monophosphate in Conditions Modeling Formalin-fixed Tissue Dehydration by Rait, Vladimir K, Zhang, Qingrong, Fabris, Daniele, Mason, Jeffrey T, O'Leary, Timothy J

“…Formalin-fixed, paraffin-embedded specimens typically provide molecular biologists with low yields of extractable nucleic acids that exhibit extensive strand…”
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Inhibitory effects of the combination of HER-2 antisense oligonucleotide and chemotherapeutic agents used for the treatment of human breast cancer by Rait, A S, Pirollo, K F, Rait, V, Krygier, J E, Xiang, L, Chang, E H

“…Poor response to chemotherapy in patients with breast cancer is often associated with overexpression of HER-2/neu. Interference with HER-2 mRNA translation by…”
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Intrinsic inhibition of aldose reductase by Kador, P F, Sun, G, Rait, V K, Rodriguez, L, Ma, Y, Sugiyama, K

“…The development of aldose reductase inhibitors for the treatment of diabetic complications, such as cataract and retinopathy, has been of intense interest in…”
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Multiplexed tissue protein assay to predict patient response to targeted therapy in advanced renal cell carcinoma by Vaishampayan, Ulka N., Sethi, Seema, Chen, Wei, Derrien-Colemyn, Alexandrine, Gillespie, John Williams, Dickow, Brenda, Smith, Daryn W., Rait, Vladimir, Tunon, Peter

“…Abstract only 382 Background: Although a number of prognostic biomarkers have been explored in advanced renal cancer, to date none have been useful in…”
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Reading, Writing, and Modulating Genetic Information with Boranophosphate Mimics of Nucleotides, DNA, and RNA by SHAW, BARBARA RAMSAY, DOBRIKOV, MIKHAIL, WANG, XIN, WAN, JING, HE, KAIZHANG, LIN, JIN-LAI, LI, PING, RAIT, VLADIMIR, SERGUEEVA, ZINAIDA A., SERGUEEV, DMITRI

“…: The P‐boranophosphates are efficient and near perfect mimics of natural nucleic acids in permitting reading and writing of genetic information with high…”
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Boranophosphate backbone: a mimic of phosphodiesters, phosphorothioates, and methyl phosphonates by Shaw, B R, Sergueev, D, He, K, Porter, K, Summers, J, Sergueeva, Z, Rait, V

“…Nucleoside boranophosphates are distinctive in that one of the non-bridging oxygens in the phosphate diester 1 is replaced by a borane moiety (BH3). Although…”
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Boranophosphates support the RNase H cleavage of polyribonucleotides by Rait, V K, Shaw, B R

“…Modification of the phosphodiester linkages in DNA by replacing one of the nonbridging oxygens with borane, BH3, produces an isoelectronic mimic of DNA called…”
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3‘-End Conjugates of Minimally Phosphorothioate-Protected Oligonucleotides with 1-O-Hexadecylglycerol:  Synthesis and Anti-ras Activity in Radiation-Resistant Cells by Rait, Antonina, Pirollo, Kathleen, Will, David W, Peyman, Anush, Rait, Vladimir, Uhlmann, Eugen, Chang, Esther H

“…Activation of the ras oncogene has been implicated in many types of human tumors. It has been shown that downmodulation of ras expression can lead to the…”
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Boranophosphate nucleic acids--a versatile DNA backbone by Rait, V, Sergueev, D, Summers, J, He, K, Huang, F, Krzyzanowska, B, Shaw, B R

“…Important chemical and biochemical properties of boranophosphate DNA and RNA oligonucleotides are reviewed. Stereoregular boranophosphate oligomers can be…”
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