Search Results - "RADU, A."

Crystal structure of a human GABAA receptor by Miller, Paul S., Aricescu, A. Radu

“…Type-A γ-aminobutyric acid receptors (GABA A Rs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABA A…”
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Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer by Laverty, Duncan, Desai, Rooma, Uchański, Tomasz, Masiulis, Simonas, Stec, Wojciech J., Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Steyaert, Jan, Miller, Keith W., Aricescu, A. Radu

“…Type A γ-aminobutyric acid (GABA A ) receptors are pentameric ligand-gated ion channels and the main drivers of fast inhibitory neurotransmission in the…”
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Anterograde C1ql1 signaling is required in order to determine and maintain a single-winner climbing fiber in the mouse cerebellum by Kakegawa, Wataru, Mitakidis, Nikolaos, Miura, Eriko, Abe, Manabu, Matsuda, Keiko, Takeo, Yukari H, Kohda, Kazuhisa, Motohashi, Junko, Takahashi, Akiyo, Nagao, Soichi, Muramatsu, Shin-ichi, Watanabe, Masahiko, Sakimura, Kenji, Aricescu, A Radu, Yuzaki, Michisuke

“…Neuronal networks are dynamically modified by selective synapse pruning during development and adulthood. However, how certain connections win the competition…”
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A GluD Coming-Of-Age Story by Yuzaki, Michisuke, Aricescu, A. Radu

“…The GluD1 and GluD2 receptors form the GluD ionotropic glutamate receptor (iGluR) subfamily. Without known endogenous ligands, they have long been referred to…”
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A study on iterative methods for solving Richards’ equation by List, Florian, Radu, Florin A.

“…This work concerns linearization methods for efficiently solving the Richards equation, a degenerate elliptic-parabolic equation which models flow in…”
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Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins by Elegheert, Jonathan, Behiels, Ester, Bishop, Benjamin, Scott, Suzanne, Woolley, Rachel E., Griffiths, Samuel C., Byrne, Eamon F. X., Chang, Veronica T., Stuart, David I., Jones, E. Yvonne, Siebold, Christian, Aricescu, A. Radu

“…Structural, biochemical and biophysical studies of eukaryotic soluble and membrane proteins require their production in milligram quantities. Although…”
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Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia by Cabău, Georgiana, Crișan, Tania O., Klück, Viola, Popp, Radu A., Joosten, Leo A. B.

“…Trained immunity is a process in which innate immune cells undergo functional reprogramming in response to pathogens or damage‐associated molecules leading to…”
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Current Status and Opportunities of Organic Thin-Film Transistor Technologies by Xiaojun Guo, Yong Xu, Ogier, Simon, Tse Nga Ng, Caironi, Mario, Perinot, Andrea, Ling Li, Jiaqing Zhao, Wei Tang, Sporea, Radu A., Nejim, Ahmed, Carrabina, Jordi, Cain, Paul, Feng Yan

“…Attributed to its advantages of super mechanical flexibility, very low-temperature processing, and compatibility with low cost and high throughput…”
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Neural network approaches for solving Schrödinger equation in arbitrary quantum wells by Radu, A., Duque, C. A.

“…In this work we approach the Schrödinger equation in quantum wells with arbitrary potentials, using the machine learning technique. Two neural networks with…”
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Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins by Matsuda, Keiko, Budisantoso, Timotheus, Mitakidis, Nikolaos, Sugaya, Yuki, Miura, Eriko, Kakegawa, Wataru, Yamasaki, Miwako, Konno, Kohtarou, Uchigashima, Motokazu, Abe, Manabu, Watanabe, Izumi, Kano, Masanobu, Watanabe, Masahiko, Sakimura, Kenji, Aricescu, A. Radu, Yuzaki, Michisuke

“…Postsynaptic kainate-type glutamate receptors (KARs) regulate synaptic network activity through their slow channel kinetics, most prominently at mossy fiber…”
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GABAA receptor signalling mechanisms revealed by structural pharmacology by Masiulis, Simonas, Desai, Rooma, Uchański, Tomasz, Serna Martin, Itziar, Laverty, Duncan, Karia, Dimple, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Kotecha, Abhay, Steyaert, Jan, Miller, Keith W., Aricescu, A. Radu

“…Type-A γ-aminobutyric (GABA A ) receptors are ligand-gated chloride channels with a very rich pharmacology. Some of their modulators, including benzodiazepines…”
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GABA A receptor signalling mechanisms revealed by structural pharmacology by Masiulis, Simonas, Desai, Rooma, Uchański, Tomasz, Serna Martin, Itziar, Laverty, Duncan, Karia, Dimple, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Kotecha, Abhay, Steyaert, Jan, Miller, Keith W, Aricescu, A Radu

“…Type-A γ-aminobutyric (GABA ) receptors are ligand-gated chloride channels with a very rich pharmacology. Some of their modulators, including benzodiazepines…”
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A synthetic synaptic organizer protein restores glutamatergic neuronal circuits by Suzuki, Kunimichi, Elegheert, Jonathan, Song, Inseon, Sasakura, Hiroyuki, Senkov, Oleg, Matsuda, Keiko, Kakegawa, Wataru, Clayton, Amber J, Chang, Veronica T, Ferrer-Ferrer, Maura, Miura, Eriko, Kaushik, Rahul, Ikeno, Masashi, Morioka, Yuki, Takeuchi, Yuka, Shimada, Tatsuya, Otsuka, Shintaro, Stoyanov, Stoyan, Watanabe, Masahiko, Takeuchi, Kosei, Dityatev, Alexander, Aricescu, A Radu, Yuzaki, Michisuke

“…Neuronal synapses undergo structural and functional changes throughout life, which are essential for nervous system physiology. However, these changes may also…”
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GluD1 binds GABA and controls inhibitory plasticity by Piot, Laura, Heroven, Christina, Bossi, Simon, Zamith, Joseph, Malinauskas, Tomas, Johnson, Chris, Wennagel, Doris, Stroebel, David, Charrier, Cécile, Aricescu, A Radu, Mony, Laetitia, Paoletti, Pierre

“…Fast synaptic neurotransmission in the vertebrate central nervous system relies primarily on ionotropic glutamate receptors (iGluRs), which drive neuronal…”
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Finite element 3D model of a double quantum ring: effects of electric and laser fields on the interband transition by Radu, A, Stan, C, Bejan, D

“…Abstract In this work, the changes in the energy of electrons and holes, oscillator strength and interband transition time when external fields are applied to…”
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Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation by Farhy-Tselnicker, Isabella, van Casteren, Adriana C.M., Lee, Aletheia, Chang, Veronica T., Aricescu, A. Radu, Allen, Nicola J.

“…The generation of precise synaptic connections between developing neurons is critical to the formation of functional neural circuits. Astrocyte-secreted…”
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Atomic-resolution monitoring of protein maturation in live human cells by NMR by Banci, Lucia, Barbieri, Letizia, Bertini, Ivano, Luchinat, Enrico, Secci, Erica, Zhao, Yuguang, Aricescu, A Radu

“…Analysis of proteins within their native environment can confirm and extend in vitro –derived conclusions. NMR analysis of superoxide dismutase 1 in live human…”
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Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent by Thimaradka, Vikram, Hoon Oh, Jae, Heroven, Christina, Radu Aricescu, A., Yuzaki, Michisuke, Tamura, Tomonori, Hamachi, Itaru

“…[Display omitted] The ability to incorporate a desired functionality into proteins of interest in a site-specific manner can provide powerful tools for…”
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Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM by Uchański, Tomasz, Masiulis, Simonas, Fischer, Baptiste, Kalichuk, Valentina, López-Sánchez, Uriel, Zarkadas, Eleftherios, Weckener, Miriam, Sente, Andrija, Ward, Philip, Wohlkönig, Alexandre, Zögg, Thomas, Remaut, Han, Naismith, James H., Nury, Hugues, Vranken, Wim, Aricescu, A. Radu, Pardon, Els, Steyaert, Jan

“…Nanobodies are popular and versatile tools for structural biology. They have a compact single immunoglobulin domain organization, bind target proteins with…”
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Structural basis for integration of GluD receptors within synaptic organizer complexes by Elegheert, Jonathan, Kakegawa, Wataru, Clay, Jordan E., Shanks, Natalie F., Behiels, Ester, Matsuda, Keiko, Kohda, Kazuhisa, Miura, Eriko, Rossmann, Maxim, Mitakidis, Nikolaos, Motohashi, Junko, Chang, Veronica T., Siebold, Christian, Greger, Ingo H., Nakagawa, Terunaga, Yuzaki, Michisuke, Aricescu, A. Radu

“…Ionotropic glutamate receptor (iGIuR) family members are integrated into supramolecular complexes that modulate their location and function at excitatory…”
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