Search Results - "RADLWIMMER, B"

De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures by Ernst, A, Campos, B, Meier, J, Devens, F, Liesenberg, F, Wolter, M, Reifenberger, G, Herold-Mende, C, Lichter, P, Radlwimmer, B

“…All- trans retinoic acid is a potent promoter of cellular differentiation processes, which is used in cancer therapy. Glioblastoma spheroid cultures are…”
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The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer by Thewes, V, Simon, R, Hlevnjak, M, Schlotter, M, Schroeter, P, Schmidt, K, Wu, Y, Anzeneder, T, Wang, W, Windisch, P, Kirchgäßner, M, Melling, N, Kneisel, N, Büttner, R, Deuschle, U, Sinn, H P, Schneeweiss, A, Heck, S, Kaulfuss, S, Hess-Stumpp, H, Okun, J G, Sauter, G, Lykkesfeldt, A E, Zapatka, M, Radlwimmer, B, Lichter, P, Tönjes, M

“…Antiestrogen-resistant and triple-negative breast tumors pose a serious clinical challenge because of limited treatment options. We assessed global gene…”
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Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins by Tagscherer, K E, Fassl, A, Campos, B, Farhadi, M, Kraemer, A, Böck, B C, Macher-Goeppinger, S, Radlwimmer, B, Wiestler, O D, Herold-Mende, C, Roth, W

“…Defects in the apoptotic signaling cascades contribute to the poor therapeutic response of malignant gliomas. As glioblastomas are characterized by high…”
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Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain by Stange, D E, Engel, F, Longerich, T, Koo, B K, Koch, M, Delhomme, N, Aigner, M, Toedt, G, Schirmacher, P, Lichter, P, Weitz, J, Radlwimmer, B

“…Liver metastases are the leading cause of death in colorectal cancer. To gain better insight into the biology of metastasis and possibly identify new…”
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Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components by Ehrbrecht, A, Müller, U, Wolter, M, Hoischen, A, Koch, A, Radlwimmer, B, Actor, B, Mincheva, A, Pietsch, T, Lichter, P, Reifenberger, G, Weber, RG

“…Desmoplastic medulloblastoma (DMB) is a malignant cerebellar tumour composed of two distinct tissue components, pale islands and desmoplastic areas. Previous…”
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DNA microarray analysis identifies candidate regions and genes in unexplained mental retardation by ENGELS, H, BROCKSCHMIDT, A, WEBER, R. G, HOISCHEN, A, LANDWEHR, C, BOSSE, K, WALLDORF, C, TOEDT, G, RADLWIMMER, B, PROPPING, P, LICHTER, P

“…Because in most patients with mental retardation (MR), who constitute 2 to 3% of the population, the etiology remains unknown, we wanted to identify novel…”
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The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele by Shetzer, Y, Kagan, S, Koifman, G, Sarig, R, Kogan-Sakin, I, Charni, M, Kaufman, T, Zapatka, M, Molchadsky, A, Rivlin, N, Dinowitz, N, Levin, S, Landan, G, Goldstein, I, Goldfinger, N, Pe'er, D, Radlwimmer, B, Lichter, P, Rotter, V, Aloni-Grinstein, R

“…p53 loss of heterozygosity (p53LOH) is frequently observed in Li-Fraumeni syndrome (LFS) patients who carry a mutant (Mut) p53 germ-line mutation. Here, we…”
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Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation by Peterziel, Heike, Müller, Julia, Danner, Andreas, Barbus, Sebastian, Liu, Hai-Kun, Radlwimmer, Bernhard, Pietsch, Torsten, Lichter, Peter, Schütz, Günther, Hess, Jochen, Angel, Peter

“…Recently, we found strong overexpression of the mucin-type glycoprotein podoplanin (PDPN) in human astrocytic brain tumors, specifically in primary…”
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Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity by Baumgarten, P., Harter, P. N., Tönjes, M., Capper, D., Blank, A.-E., Sahm, F., von Deimling, A., Kolluru, V., Schwamb, B., Rabenhorst, U., Starzetz, T., Kögel, D., Rieker, R. J., Plate, K. H., Ohgaki, H., Radlwimmer, B., Zörnig, M., Mittelbronn, M.

“…Aims The Far Upstream Element [FUSE] Binding Protein 1 (FUBP1) regulates target genes, such as the cell cycle regulators MYC and p21. FUBP1 is up‐regulated in…”
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294: In vitro modulation of CITED4 gene expression in a colorectal cancer cell line by Rogers, M.A, Kalter, V, Marcias, G, Zapatka, M, Barbus, S, Radlwimmer, B, Lichter, P

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RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival by Goidts, V, Bageritz, J, Puccio, L, Nakata, S, Zapatka, M, Barbus, S, Toedt, G, Campos, B, Korshunov, A, Momma, S, Van Schaftingen, E, Reifenberger, G, Herold-Mende, C, Lichter, P, Radlwimmer, B

“…The concept of cancer stem-like cells (CSCs) has gained considerable attention in various solid tumors including glioblastoma, the most common primary brain…”
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Frequent loss of chromosome 9, homozygous CDKN2A/p14(ARF)/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas by Weber, R G, Hoischen, A, Ehrler, M, Zipper, P, Kaulich, K, Blaschke, B, Becker, A J, Weber-Mangal, S, Jauch, A, Radlwimmer, B, Schramm, J, Wiestler, O D, Lichter, P, Reifenberger, G

“…The molecular pathogenesis of pleomorphic xanthoastrocytoma (PXA), a rare astrocytic brain tumor with a relatively favorable prognosis, is still poorly…”
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The "five-sites" rule and the evolution of red and green color vision in mammals by Yokoyama, S, Radlwimmer, F B

“…Amino acid changes S180A (S-->A at site 180), H197Y, Y277F, T285A, and A308S are known to shift the maximum wavelength of absorption (lambda max) of red and…”
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Frequent loss of chromosome 9, homozygous CDKN2A/p14ARF/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas by WEBER, R. G, HOISCHEN, A, SCHRAMM, J, WIESTLER, O. D, LICHTER, P, REIFENBERGER, G, EHRLER, M, ZIPPER, P, KAULICH, K, BLASCHKE, B, BECKER, A. J, WEBER-MANGAL, S, JAUCH, A, RADLWIMMER, B

“…The molecular pathogenesis of pleomorphic xanthoastrocytoma (PXA), a rare astrocytic brain tumor with a relatively favorable prognosis, is still poorly…”
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348: BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 by Radlwimmer, B, Tönjes, M, Barbus, S, Park, Y.J, Wang, W, Weibrecht, I, Hutson, S.M, Plass, C, Reifenberger, G, Lichter, P

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COMPREHENSIVE EPIGENETIC AND TRANSCRIPTIONAL SURVEY OF THE “IMPRINTOME” IN NORMAL B‐CELLS AND GERMINAL CENTER DERIVED B‐CELL LYMPHOMAS OF THE MMML AND ICGC MMML‐SEQ NETWORKS by Bens, S., Kolarova, J., Kreuz, M., Bernhart, S., Kretzmer, H., Wagener, R., Küppers, R., Ammerpohl, O., Burkhardt, B., Hoffmann, S., Hummel, M., Klapper, W., Lichter, P., Löffler, M., Möller, P., Radlwimmer, B., Rosenstiel, P., Stein, H., Trümper, L., Siebert, R.

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Molecular Genetics and the Evolution of Ultraviolet Vision in Vertebrates by Shi, Yongsheng, Radlwimmer, F. Bernhard, Yokoyama, Shozo

“…Despite the biological importance of UV vision, its molecular bases are not well understood. Here, we present evidence that UV vision in vertebrates is…”
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32LBA High level gene amplification of MYC characterizes radiation-induced angiosarcomas by Hohenberger, P, Mössinger, K, Manner, J, Radlwimmer, B, Lichter, P, Sciot, R, Coindre, J.M, Katenkamp, D, Ströbel, P

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Tumor stem cells in gliomas – clinical impact of the stem cell marker CD133 and therapeutical strategies by Herold-Mende, C, Campos, B, Wan, F, Zeppernick, F, Ahmadi, R, Roth, W, Lichter, P, Unterberg, A, Radlwimmer, B

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A Chromosome 8 Gene-Cluster Polymorphism with Low Human Beta-Defensin 2 Gene Copy Number Predisposes to Crohn Disease of the Colon by Fellermann, Klaus, Stange, Daniel E., Schaeffeler, Elke, Schmalzl, Hartmut, Wehkamp, Jan, Bevins, Charles L., Reinisch, Walter, Teml, Alexander, Schwab, Matthias, Lichter, Peter, Radlwimmer, Bernhard, Stange, Eduard F.

“…Defensins are endogenous antimicrobial peptides that protect the intestinal mucosa against bacterial invasion. It has been suggested that deficient defensin…”
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