Search Results - "RAABE, O. G"

Cellular reprogramming in the F3 mouse with paternal F0 radiation history by VANCE, M. M, BAULCH, J. E, RAABE, O. G, WILEY, L. M, OVERSTREET, J. W

“…In the mouse, paternal F0 acute irradiation of Type B spermatogonia produces biological effects in offspring, including altered signalling kinase activities…”
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Aerosol delivery of lipid:DNA complexes to lungs of rhesus monkeys by MCDONALD, R. J, LIGGITT, H. D, ROCHE, L, NGUYEN, H. T, PEARLMAN, R, RAABE, O. G, BUSSEY, L. B, GORMAN, C. M

“…The potential use of aerosol delivery for non-viral gene therapy was tested by nebulization of lipid:DNA complexes to the lungs of rhesus monkeys. Four female…”
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Paternal Effects from Methamidophos Administration in Mice by Burruel, Victoria R., Raabe, Otto G., Overstreet, James W., Wilson, Barry W., Wiley, Lynn M.

“…In this study, the mouse was used to evaluate paternal germline exposure to the organophosphate methamidophos for its potential to produce adverse effects on…”
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Is the Linear-No-Threshold Hypothesis Appropriate for Use in Radiation Protection? by Brenner, D J, Raabe, O G

“…Contemporary radiation protection practices are strongly influenced by the fundamental assumptions related to the actions of ionising radiation at low levels…”
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Topics Under Debate - Is the Linear-No-Threshold Hypothesis Appropriate for Use in Radiation Protection? by D. J. Brenner, Proposer, O. G. Raabe, Opposer, J. C. McDonald, Moderator

“…There are few things more important to the practice of radiation protection than the basic assumptions regarding the actions of ionising radiation at low…”
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Impaired Cell Proliferation in Mice That Persists across at Least Two Generations after Paternal Irradiation by Wiley, Lynn M., Baulch, Janet E., Raabe, Otto G., Straume, Tore

“…Irradiation of male F0 mice 6 to 7 weeks prior to mating causes significant changes in the proliferation of F1 and F2 embryonic cells. These changes are…”
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Toxicokinetic modeling of dose-dependent formate elimination in rats : In vivo-In vitro correlations Using the perfused rat liver by DAMIAN, P, RAABE, O. G

“…The dose-dependent elimination of formate was investigated in the rat using both in vitro and in vivo systems. The in situ perfused liver was used to define…”
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Bone Sarcoma Characteristics and Distribution in Beagles Fed Strontium-90 by White, R. G., Raabe, O. G., Culbertson, M. R., Parks, N. J., Samuels, S. J., Rosenblatt, L. S.

“…A total of 66 primary bone sarcomas were diagnosed in 47 beagles; 43 of these dogs were part of the 403 beagles fed 90 Sr and 4 were part of the 162 controls…”
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Bone Sarcoma Characteristics and Distribution in Beagles Injected with Radium-226 by White, R. G., Raabe, O. G., Culbertson, M. R., Parks, N. J., Samuels, S. J., Rosenblatt, L. S.

“…A total of 155 primary bone sarcomas were found in 131 of the 246 beagles injected with 226 Ra and 5 primary bone sarcomas were found in 4 of the 158 unexposed…”
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Particle inhalability curves for humans and small laboratory animals by Ménache, M G, Miller, F J, Raabe, O G

“…Several inhalability curves for nose breathing in humans have been developed. No studies have been designed specifically to develop inhalability functions for…”
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Paternally Inherited Effects of γ Radiation on Mouse Preimplantation Development Detected by the Chimera Assay by Warner, Petra, Wiley, Lynn M., Oudiz, Deborah J., Overstreet, James W., Raabe, Otto G.

“…It has previously been shown that type B spermatogonia in male mice treated with 0.05 Gy of X rays undergo an alteration expressed by progeny embryos as a…”
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Is the linear-no-threshold hypothesis appropriate for use in radiation protection? Opposing the proposition by Raabe, O G

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Heritable effects of paternal irradiation in mice on signaling protein kinase activities in F3 offspring by Baulch, Janet E., Raabe, Otto G., Wiley, Lynn M.

“…We evaluated F3 mouse offspring from paternal F0 attenuated 137Cs γ-irradiation (1.0 Gy) for heritable effects on gene products that can modulate cell…”
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Interspecies scaling of risk for radiation-induced bone cancer by Raabe, O G, Rosenblatt, L S, Schlenker, R A

“…The induction of bone cancer in mice, dogs and humans, due to protracted alpha-irradiation from skeletal burdens of radium, was found to be represented by a…”
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Clinical comparison of Gentle-Haler Actuator and Aerochamber Spacer for Metered Dose Inhaler (MDI) use by asthmatics by Chipps, B E, Naumann, P F, Wong, G A, Raabe, O G

“…Spacing devices such as the Aerochamber have been shown to improve delivery of medication from MDIs in patients who could not use proper technique with an MDI…”
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Scaling of fatal cancer risks from laboratory animals to man by Raabe, O G

“…The functionally injurious and carcinogenic responses after exposure to 226Ra in mice, beagles, and people are reviewed. The observed bone-cancer response…”
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Radionuclides in fishes and mussels from the Farallon Islands Nuclear Waste Dump Site, California by Suchanek, T H, Lagunas-Solar, M C, Raabe, O G, Helm, R C, Gielow, F, Peek, N, Carvacho, O

“…The Farallon Islands Nuclear Waste Dump Site (FINWDS), approximately 30 miles west of San Francisco, California, received at least 500 TBq encapsulated in more…”
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Establishing aerosol exposure concentrations for inhalation toxicity studies by Lewis, T R, Morrow, P E, McClellan, R O, Raabe, O G, Kennedy, G L, Schwetz, B A, Goehl, T J, Roycroft, J H, Chhabra, R S

“…Criteria for the selection of aerosol concentrations to be used in inhalation studies assessing the toxicity and carcinogenicity of chemical substances were…”
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UNDERSTANDING IONIZING RADIATION CARCINOGENESIS by Raabe, O G

“…The current framework for estimating the risk of cancer induction for exposure to ionizing radiation is, unfortunately, based on misunderstandings. Radiation…”
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Time and dose-response study of the effects of vanadate on rats: morphological and biochemical changes in organs by al-Bayati, M A, Giri, S N, Raabe, O G, Rosenblatt, L S, Shifrine, M

“…Vanadate at a dosage level of 0.9 mg V/kg per day produced acute toxic signs in rats when injected subcutaneously for 16 days. These signs were weakness, loss…”
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