Search Results - "R.R. Kay"

DIF-1 induces its own breakdown in Dictyostelium by Insall, R, Nayler, O, Kay, R.R

“…DIF-1 is a novel chlorinated alkyl phenone which induces differentiation of prestalk cells in Dictyostelium discoideum. It is broken down and inactivated by a…”
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New roles for DIF? Effects on early development in Dictyostelium by Wurster, B., Kay, R.R.

“…The DIFs are unusual, chlorinated molecules which induce stalk cell differentiation during the later, multicellular phase of Dictyostelium development. Here we…”
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Dictyostelium mutants lacking DIF, a putative morphogen by Kopachik, W, Oohata, A, Dhokia, B, Brookman, J J, Kay, R R

“…DIF is an endogenous extracellular signal that may control differentiation of D. discoideum cells. It is a dialyzable, lipid-like factor that induces stalk…”
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The biosynthesis of differentiation-inducing factor, a chlorinated signal molecular regulating Dictyostelium development by Kay, R.R

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intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium by Thomason, P.A, Traynor, D, Cavet, G, Chang, W.T, Harwood, A.J, Kay, R.R

“…Terminal differentiation of both stalk and spore cells in Dictyostelium can be triggered by activation of cAMP‐dependent protein kinase (PKA). A screen for…”
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Glycogen synthase kinase 3 regulates cell fate in dictyostelium by Harwood, A.J, Plyte, S.E, Woodgett, J, Strutt, H, Kay, R.R

“…Extracellular cyclic AMP (cAMP) induces the formation of prespore cells in Dictyostelium but inhibits stalk cell formation. We have cloned gskA, which encodes…”
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The RdeA-RegA System, a Eukaryotic Phospho-relay Controlling cAMP Breakdown by Thomason, Peter A., Traynor, David, Stock, Jeffry B., Kay, Robert R.

“…The regA and rdeA gene products of Dictyostelium are involved in the regulation of cAMP signaling. The response regulator, RegA, is composed of an N-terminal…”
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Dictyostelium genome project an invitation to species hopping by Kay, R.R, Williams, J.G

“…Dictyostelium allows some of the general problems of eukaryotic biology to be addressed by using molecular genetic tools that are more normally associated with…”
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Evidence that elevated intracellular cyclic AMP maturation in Dictyostelium by R.R. Kay

“…Spore maturation occurs during normal development in when environmental influences induce a migrating slug a fruiting body. As the amoeboid prespore cells turn…”
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Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum by Berks, M, Kay, R R

“…At least three distinct types of cell arise from a population of similar amoebae during Dictyostelium development: prespore, prestalk A and prestalk B cells…”
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Mutation of protein kinase A causes heterochronic development of Dictyostelium by Simon, M.N, Pelegrini, O, Veron, M, Kay, R.R

“…In heterochronic mutants the relative timing of developmental events is altered compared with the wild type. This generally results in a disordered embryo,…”
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Overexpression of Dd PK2 protein kinase causes rapid development and affects the intracellular cAMP pathway of Dictyostelium discoideum by ANJARD, C, PINAUD, S, KAY, R. R, REYMOND, C. D

“…The Dd PK2 gene codes for a putative protein of 648 amino acids with a C-terminal half sharing high homology with protein kinase A catalytic subunits from…”
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Direct induction of Dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen by Williams, J G, Ceccarelli, A, McRobbie, S, Mahbubani, H, Kay, R R, Early, A, Berks, M, Jermyn, K A

“…We have isolated a gene that is very rapidly induced at the transcriptional level by DIF--a low molecular weight, diffusible factor necessary for stalk cell…”
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A localized differentiation-inducing-factor sink in the front of the Dictyostelium slug by Kay, Robert R., Large, Sara, Traynor, David, Nayler, Oliver

“…Differentiation-inducing factor 1 [DIF-1; 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)-hexan-1-one] induces stalk cell differentiation during Dictyostelium…”
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cAMP and spore differentiation in Dictyostelium discoideum by Kay, R.R

“…The individual amoebae composing a Dictyostelium aggregate can differentiate into either stalk or spore cells according, it is believed, to the extracellular…”
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The impact of multiplexing on the dynamic requirements of analog-to-digital converters by Sobering, T.J., Kay, R.R.

“…In data acquisition applications where the signals being digitized are produced in a time-division multiplexed system, the required dynamic performance of the…”
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Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum by Morris, H.R, Masento, M.S, Taylor, G.W, Jermyn, K.A, Kay, R.R

“…Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium…”
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Nature and distribution of the morphogen DIF in the Dictyostelium slug by Brookman, J J, Jermyn, K A, Kay, R R

“…The Dictyostelium slug contains a simple anterior-posterior pattern of prestalk and prespore cells. It is likely that DIF, the morphogen which induces stalk…”
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Differentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues. Synthesis, structure and biological activity by Masento, M.S, Morris, H.R, Taylor, G.W, Johnson, S.J, Skapski, A.C, Kay, R.R

“…Previous work has led to the identification of a novel class of effector molecules [DIFs (differentiation-inducing factors) 1-3] released from the slime mould…”
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Requirement for cell differentiation in Dictyostelium discoideum by Kay, R.R, Garrod, D, Tilly, R

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