Search Results - "R. Morán, Joaquín"
-
1
5‑Chloro-8-nitro-1-naphthoyl (NNap): A Selective Protective Group for Amines and Amino Acids
Published in Organic letters (09-06-2023)“…The synthesis of 5-chloro-8-nitro-1-naphthoyl chloride and its use as a protective group for amines is described. Protection is carried out with an auxiliary…”
Get full text
Journal Article -
2
Highly Enantioselective Extraction of Phenylglycine by a Chiral Macrocyclic Receptor Based on Supramolecular Interactions
Published in Organic letters (07-02-2020)“…Using supramolecular interactions, a novel macrocyclic receptor is able to selectively extract zwitterionic phenylglycine from neutral aqueous solutions into…”
Get full text
Journal Article -
3
Transesterification of Non‐Activated Esters Promoted by Small Molecules Mimicking the Active Site of Hydrolases
Published in Angewandte Chemie International Edition (26-08-2022)“…The synthesis of small molecules able to mimic the active site of hydrolytic enzymes has been largely pursued in recent decades. The high reaction rates and…”
Get full text
Journal Article -
4
An Enzyme Model Which Mimics Chymotrypsin and N‑Terminal Hydrolases
Published in ACS catalysis (02-10-2020)“…Enzymes are the most efficient and specific catalysts to date. Although they have been thoroughly studied for years, building a true enzyme mimic remains a…”
Get full text
Journal Article -
5
An Adjustable Cleft Based on an 8‐Sulfonamide‐2‐Naphthoic Acid with Oxyanion Hole Geometry
Published in Chemistry : a European journal (21-10-2021)“…Cleft type receptors showing the oxyanion hole motif have been prepared in a straightforward synthesis starting from the commercial 3,7‐dihidroxy‐2‐naphthoic…”
Get full text
Journal Article -
6
A molecular receptor selective for zwitterionic alanine
Published in Organic & biomolecular chemistry (2017)“…A molecular receptor has been synthesized joining an aza-crown ether with a chiral chromane which mimics the oxyanion hole of the enzymes. With this receptor…”
Get more information
Journal Article -
7
Synthesis of Monoacylated Derivatives of 1,2- Cyclohexanediamine. Evaluation of their Catalytic Activity in the Preparation of Wieland−Miescher Ketone
Published in Journal of organic chemistry (03-12-2010)“…Ureas, carbamoyl derivatives, amides, and sulfonamides can be easily prepared from the strained (R,R)-cylohexanediamine urea (1) in high yield, leaving a free…”
Get full text
Journal Article -
8
Bifunctional organocatalysts based on a carbazole scaffold for the synthesis of the Hajos–Wiechert and Wieland–Miescher ketones
Published in Tetrahedron (25-02-2015)“…Several bifunctional organocatalysts based on a carbazole scaffold containing a chiral amine and a synthetic oxyanion-hole have been synthesized and…”
Get full text
Journal Article -
9
A bio-inspired enantioselective small-molecule artificial receptor for β adrenergic agonists and antagonists and its application for enantioselective extraction
Published in Chemical communications (Cambridge, England) (01-01-2016)“…Administration of enantiomerically pure β-adrenergic agonists and antagonists increases their activity and reduces side effects. We report here a…”
Get more information
Journal Article -
10
A molecular receptor for zwitterionic phenylalanine
Published in Organic & biomolecular chemistry (28-04-2016)“…The combination of a 1,3-ketoenol system and two pyridine molecules attached as sulfonamide and carboxamide to a benzofuran skeleton allows the preparation of…”
Get more information
Journal Article -
11
Chiral recognition with a benzofuran receptor that mimics an oxyanion hole
Published in Organic & biomolecular chemistry (14-01-2015)“…A new chiral benzofuran receptor has been synthesized and its properties in the association of amino acid derivatives have been studied. X-ray structures were…”
Get more information
Journal Article -
12
Proline imidazolidinones and enamines in Hajos–Wiechert and Wieland–Miescher ketone synthesis
Published in Tetrahedron (20-06-2009)“…Readily available aromatic prolinamides obtained from the acid chloride of proline hydrochloride and anilines induce large enantiomeric excesses in…”
Get full text
Journal Article -
13
A highly selective receptor for zwitterionic proline
Published in Organic & biomolecular chemistry (01-01-2016)“…A chiral chromane receptor has been synthesized which mimics the oxyanion hole of the enzymes. In this receptor H-bonds and cation-π interactions team up to…”
Get more information
Journal Article -
14
Sulfonamide carbazole receptors for anion recognition
Published in Organic & biomolecular chemistry (21-12-2011)“…Carbazole-based receptors functionalized with two sulfonamide groups have been synthesized and their properties as anion receptors have been evaluated. The…”
Get more information
Journal Article -
15
A High Yield Procedure for the Preparation of 2-Hydroxynitrostyrenes: Synthesis of Imines and Tetracyclic 1,3-Benzoxazines
Published in European journal of organic chemistry (01-05-2014)“…Attempts to synthesize 2‐hydroxynitrostyrenes by a Knoevenagel condensation of salicylaldehyde and subsequent elimination were unsuccessful because of the…”
Get full text
Journal Article -
16
Preparation of cyclic boramides from salicylaldehydes, ammonium acetate and sodium borohydride
Published in Tetrahedron (11-11-2014)“…Borohydride reduction of salicylaldehyde imines yields surprisingly a cyclic boramide. This is a fairly stable compound, and X-ray analysis shows it has a…”
Get full text
Journal Article -
17
Macrocyclic Chiral Receptors toward Enantioselective Recognition of Naproxen
Published in Organic letters (12-10-2006)“…A macrocyclic receptor based on a bischromenylurea and an α,α‘-(o,o ‘-dialkyl)diphenyl-p-xylylenediamine spacer provides a C 2 chiral cavity to associate…”
Get full text
Journal Article -
18
A Twitchell Reagent Revival: Biodiesel Generation from Low Cost Oils
Published in Advanced synthesis & catalysis (01-10-2011)“…The transesterification of triglycerides with short‐chain alcohols, such as methanol, is the most used process for the obtention of biodiesel. This is a…”
Get full text
Journal Article -
19
A Xanthene-Benzimidazole Receptor with Multiple H-Bond Donors for Carboxylic Acids
Published in European Journal of Organic Chemistry (01-11-2010)“…The combination of two benzimidazole moieties with a spacer formed by a leucine unit and a xanthene skeleton provides an efficient receptor for neutral guests…”
Get full text
Book Review Journal Article -
20
Thiourea versus the oxyanion hole as a double H-bond donor
Published in Tetrahedron letters (18-08-2008)“…A novel receptor based on the 4,5-diamine-9,9-dimethylxanthene skeleton functionalised with triflamides has been developed and its hydrogen-bonding donor…”
Get full text
Journal Article