Search Results - "R. Matyas, John"

Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction by Eaton, Malcolm, Davies, Alastair H, Devine, Jay, Zhao, Xiang, Simmons, David G, Maríusdóttir, Elín, Natale, David R C, Matyas, John R, Bering, Elizabeth A, Workentine, Matthew L, Hallgrimsson, Benedikt, Cross, James C

“…The major milestones in mouse placental development are well described, but our understanding is limited to how the placenta can adapt to damage or changes in…”
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Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity by Krawetz, Roman J., Wu, Yiru Elizabeth, Bertram, Karri L., Shonak, Anchita, Masson, Anand O., Ren, Guomin, Leonard, Catherine, Kapoor, Mohit, Matyas, John R., Salo, Paul T.

“…Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from…”
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Enumeration and Localization of Mesenchymal Progenitor Cells and Macrophages in Synovium from Normal Individuals and Patients with Pre-Osteoarthritis or Clinically Diagnosed Osteoarthritis by O'Brien, Kate, Tailor, Pankaj, Leonard, Catherine, DiFrancesco, Lisa M, Hart, David A, Matyas, John R, Frank, Cyril B, Krawetz, Roman J

“…Osteoarthritis (OA) is a degenerative disorder characterized by chondrocyte apoptosis and degeneration of articular cartilage resulting in loss of mobility and…”
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Role of Primary Afferents in Arthritis Induced Spinal Microglial Reactivity by Kwok, Charlie H T, Kohro, Yuta, Mousseau, Michael, O'Brien, Melissa S, Matyas, John R, McDougall, Jason J, Trang, Tuan

“…Increased afferent input resulting from painful injury augments the activity of central nociceptive circuits both neuron-neuron and neuron-glia interactions…”
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The innervation of the human acetabular labrum and hip joint: an anatomic study by Alzaharani, Abdullah, Bali, Kamal, Gudena, Ravi, Railton, Pamela, Ponjevic, Dragana, Matyas, John R, Powell, James N

“…The aim of the current study was to evaluate the innervation of the acetabular labrum in the various zones and to understand its potential role in nociception…”
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Synovial fluid progenitors expressing CD90+ from normal but not osteoarthritic joints undergo chondrogenic differentiation without micro-mass culture by Krawetz, Roman J, Wu, Yiru Elizabeth, Martin, Liam, Rattner, Jerome B, Matyas, John R, Hart, David A

“…Mesenchymal progenitor cells (MPCs) can differentiate into osteoblasts, adipocytes, and chondrocytes, and are in part responsible for maintaining tissue…”
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Microglial pannexin-1 channel activation is a spinal determinant of joint pain by Mousseau, Michael, Burma, Nicole E, Lee, Kwan Yeop, Leduc-Pessah, Heather, Kwok, Charlie H T, Reid, Allison R, O'Brien, Melissa, Sagalajev, Boriss, Stratton, Jo Anne, Patrick, Natalya, Stemkowski, Patrick L, Biernaskie, Jeff, Zamponi, Gerald W, Salo, Paul, McDougall, Jason J, Prescott, Steven A, Matyas, John R, Trang, Tuan

“…Chronic joint pain such as mechanical allodynia is the most debilitating symptom of arthritis, yet effective therapies are lacking. We identify the pannexin-1…”
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Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison by Hunter, Christopher J., Matyas, John R., Duncan, Neil A.

“…The nuclei pulposi of the intervertebral discs (IVDs) contain a mixed population of cell types at various stages of maturation. This tissue is formed either by…”
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Collagen integrity of the annulus fibrosus in degenerative disc disease individuals quantified with collagen hybridizing peptide by Dhiman, Manmeet S., Bader, Taylor J., Ponjevic, Dragana, Salo, Paul T., Hart, David A., Swamy, Ganesh, Matyas, John R., Duncan, Neil A.

“…Introduction Degenerative disc disease (DDD) is accompanied by structural changes in the intervertebral discs (IVD). Extra‐cellular matrix degradation of the…”
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ISSLS prize winner: Collagen fibril sliding governs cell mechanics in the anulus fibrosus an in situ confocal microscopy study of bovine discs by BRUEHLMANN, Sabina B, MATYAS, John R, DUNCAN, Neil A

“…In situ investigation of collagen and cell mechanics in bovine caudal discs using novel techniques of confocal microscopy. To measure simultaneously the in…”
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Reduced differentiation efficiency of murine embryonic stem cells in stirred suspension bioreactors by Taiani, Jaymi T, Krawetz, Roman J, Zur Nieden, Nicole I, Elizabeth Wu, Yiru, Kallos, Michael S, Matyas, John R, Rancourt, Derrick E

“…The use of embryonic stem cells (ESCs) for regenerative medicine has generated increased attention due to the favorable attributes of these cells; namely, they…”
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The functional microstructure of tendon collagen revealed by high-field MRI by Mountain, Kelsey M., Bjarnason, Thorarin A., Dunn, Jeff F., Matyas, John R.

“…T2 was used in this study to assess tendon microstructure. Two unloaded digital extensor tendons were bent such that their long axes were imaged throughout…”
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Regional variations in the cellular matrix of the annulus fibrosus of the intervertebral disc by Bruehlmann, Sabina B., B. Rattner, Jerome, R. Matyas, John, A. Duncan, Neil

“…The three‐dimensional architecture of cells in the annulus fibrosus was studied by a systematic, histological examination using antibodies to cytoskeletal…”
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Embryonic stem cells incorporate into newly formed bone and do not form tumors in an immunocompetent mouse fracture model by Taiani, Jaymi T, Krawetz, Roman J, Yamashita, Akihiro, Pauchard, Yves, Buie, Helen R, Ponjevic, Dragana, Boyd, Steven K, Rancourt, Derrick E, Matyas, John R

“…Embryonic stem (ES) cells are a uniquely self-renewing, pluripotent population of cells that must be differentiated before being useful for cell therapy. Since…”
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The functional significance of cell clusters in the notochordal nucleus pulposus: Survival and signaling in the canine intervertebral disc by HUNTER, Christopher J, MATYAS, John R, DUNCAN, Neil A

“…Cell viability was assessed in relation to cell clustering, and mechanisms of cell-cell signaling in the clusters were investigated. To explore the functional…”
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Correction: Synovial Fluid Progenitors Expressing CD90+ from Normal but Not Osteoarthritic Joints Undergo Chondrogenic Differentiation without Micro-Mass Culture by Krawetz, Roman J., Wu, Yiru Elizabeth, Martin, Liam, Rattner, Jerome B., Matyas, John R., Hart, David A.

“…Citation: Krawetz RJ, Wu YE, Martin L, Rattner JB, Matyas JR, Hart DA (2012) Correction: Synovial Fluid Progenitors Expressing CD90+ from Normal but Not…”
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Contrast-enhanced x-ray microscopy of articular cartilage by Zhu, Ying, Ponjevic, Dragana, Matyas, John R, Boyd, Steven K

“…Osteoarthritis is a common chronic disease of joints characterized by degenerative changes of articular cartilage. An early diagnosis of osteoarthritis may be…”
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Communication between paired chondrocytes in the superficial zone of articular cartilage by Chi, Simon S., Rattner, Jerome B., Matyas, John R.

“…The regeneration and repair of cartilage damaged by injury or disease, a major goal of orthopaedic science, depends on understanding the structure and function…”
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Full-Length Recombinant Human Proteoglycan 4 Interacts with Hyaluronan to Provide Cartilage Boundary Lubrication by Abubacker, Saleem, Dorosz, Samuel G., Ponjevic, Dragana, Jay, Gregory D., Matyas, John R., Schmidt, Tannin A.

“…Proteoglycan 4 (PRG4) is a mucin-like glycoprotein present in synovial fluid and at the surface of articular cartilage. The objectives of this study were to…”
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Cage-lid hanging behavior as a translationally relevant measure of pain in mice by Zhang, Hantao, Lecker, Irene, Collymore, Chereen, Dokova, Anastassia, Pham, Maian Christine, Rosen, Sarah F., Crawhall-Duk, Hayley, Zain, Maham, Valencia, Megan, Filippini, Helena Fetter, Li, Jerry, D'Souza, Abigail J., Cho, Chulmin, Michailidis, Vassilia, Whissell, Paul D., Patel, Ingita, Steenland, Hendrik W., Virginia Lee, Wai-Jane, Moayedi, Massieh, Sterley, Toni-Lee, Bains, Jaideep S., Stratton, Jo Anne, Matyas, John R., Biernaskie, Jeff, Dubins, David, Vukobradovic, Igor, Bezginov, Alexandr, Flenniken, Ann M., Martin, Loren J., Mogil, Jeffrey S., Bonin, Robert P.

“…The development of new analgesic drugs has been hampered by the inability to translate preclinical findings to humans. This failure is due in part to the weak…”
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