Search Results - "R. Kohnen"

Co-evolution of tumor and immune cells during progression of multiple myeloma by Liu, Ruiyang, Gao, Qingsong, Foltz, Steven M., Fowles, Jared S., Yao, Lijun, Wang, Julia Tianjiao, Cao, Song, Sun, Hua, Wendl, Michael C., Sethuraman, Sunantha, Weerasinghe, Amila, Rettig, Michael P., Storrs, Erik P., Yoon, Christopher J., Wyczalkowski, Matthew A., McMichael, Joshua F., Kohnen, Daniel R., King, Justin, Goldsmith, Scott R., O’Neal, Julie, Fulton, Robert S., Fronick, Catrina C., Ley, Timothy J., Jayasinghe, Reyka G., Fiala, Mark A., Oh, Stephen T., DiPersio, John F., Vij, Ravi, Ding, Li

“…Multiple myeloma (MM) is characterized by the uncontrolled proliferation of plasma cells. Despite recent treatment advances, it is still incurable as disease…”
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Evolution and structure of clinically relevant gene fusions in multiple myeloma by Foltz, Steven M., Gao, Qingsong, Yoon, Christopher J., Sun, Hua, Yao, Lijun, Li, Yize, Jayasinghe, Reyka G., Cao, Song, King, Justin, Kohnen, Daniel R., Fiala, Mark A., Ding, Li, Vij, Ravi

“…Multiple myeloma is a plasma cell blood cancer with frequent chromosomal translocations leading to gene fusions. To determine the clinical relevance of fusion…”
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Acute treatment of moderate to severe depression with hypericum extract WS 5570 (St John's wort): randomised controlled double blind non-inferiority trial versus paroxetine by Szegedi, A, Kohnen, R, Dienel, A, Kieser, M

“…Abstract Objective To investigate the efficacy of hypericum extract WS 5570 (St John's wort) compared with paroxetine in patients with moderate to severe major…”
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Effective cabergoline treatment in idiopathic restless legs syndrome by STIASNY-KOLSTER, K, BENES, H, PEGLAU, I, HORNYAK, M, HOLINKA, B, WESSEL, K, EMSER, W, LEROUX, M, KOHNEN, R, OERTEL, W. H

“…To assess the efficacy and safety of the dopamine agonist cabergoline (CAB) in patients with restless legs syndrome (RLS). Patients with moderate to severe RLS…”
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Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: Results from a multi-center, randomized, active controlled trial by Trenkwalder, Claudia, Benes, Heike, Grote, Ludger, Happe, Svenja, Högl, Birgit, Mathis, Johannes, Saletu-Zyhlarz, Gerda M., Kohnen, Ralf

“…We report the first large‐scale double‐blind, randomly assigned study to compare two active dopaminergic therapies for Restless Legs Syndrome (RLS), the…”
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Cognitive behavioural group therapy to improve patients’ strategies for coping with restless legs syndrome: a proof-of-concept trial by Hornyak, M, Grossmann, C, Kohnen, R, Schlatterer, M, Richter, H, Voderholzer, U, Riemann, D, Berger, M

“…Background:Restless legs syndrome (RLS) is a usually chronic disorder accompanied by clinically relevant psychosocial impairment. To date, no psychologically…”
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Efficacy and tolerability of an ulcer compression stocking for therapy of chronic venous ulcer compared with a below-knee compression bandage: results from a prospective, randomized, multicentre trial by Jünger, M., Wollina, U., Kohnen, R., Rabe, E.

“…SUMMARY Objective: To investigate the possibility of improving healing rates in ulcus cruris venosum by using an ulcer compression stocking (U-Stocking)…”
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S25.D Quality of life in restless legs syndrome by Kohnen, R

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The prevalence and characteristics of patients with classic locked-in syndrome in Dutch nursing homes by Kohnen, R. F., Lavrijsen, J. C. M., Bor, J. H. J., Koopmans, R. T. C. M.

“…To establish the point prevalence and characteristics of patients with locked-in syndrome (LIS), particularly of the classic type, residing in Dutch nursing…”
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Efficacy of cabergoline in restless legs syndrome : A placebo-controlled study with polysomnography (CATOR) by OERTEL, W. H, BENES, H, STIASNY-KOLSTER, K, BODENSCHATZ, R, PEGLAU, I, WARMUTH, R, HAPPE, S, GEISLER, P, CASSEL, W, LEROUX, M, KOHNEN, R

“…To assess the efficacy and safety of the dopamine agonist cabergoline in the treatment of patients with idiopathic restless legs syndrome (CATOR study)…”
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Mirtazapine compared with paroxetine in major depression by BENKERT, Otto, SZEGEDI, Armin, KOHNEN, Ralf

“…The aim was to compare the efficacy and tolerability of mirtazapine with those of paroxetine. 275 outpatients with a diagnosis of major depressive episode…”
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Loss of response during long-term treatment of restless legs syndrome: Guidelines approved by the International Restless Legs Syndrome Study Group for use in clinical trials by Garcia-Borreguero, D, Allen, R, Kohnen, R, Benes, H, Winkelman, J, Högl, B, Ferini-Strambi, L, Zucconi, M, Trenkwalder, C

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No augmentation during opioid treatment in restless legs syndrome – Results from a 1 year long-term trial by Kohnen, R, Bosse, B, Hopp, M, Winkelmann, J, Allen, R, Trenkwalder, C

“…Introduction Dopaminergic treatments, the mainstay of restless legs syndrome (RLS) therapy, are often associated with augmentation (worsening of RLS symptom…”
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Sleep in restless legs syndrome improves during opioid treatment – Results from a large 1-year multi-center trial by Benes, H, Trenkwalder, C, Garcia-Borreguero, D, Bosse, B, Hopp, M, Kohnen, R

“…Introduction In severe cases of restless legs syndrome (RLS), symptoms result in bothersome impact on sleep and impairment of daytime function. This study…”
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Opioid treatment is efficacious in the short- and long-term in patients with severe restless legs syndrome after failure of previous medications by Trenkwalder, C, Benes, H, Garcia-Borreguero, D, Grote, L, Hopp, M, Kohnen, R

“…Introduction Opioids are mainstay for pain therapy and used in several countries as off-label therapy in RLS after failure of first-line therapy. This study…”
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EPA-0703 – Performance of the hamilton depression rating subscales to predict antidepressant treatment response in the early course of treatment by Helmreich, I, Wagner, S, König, J, Kohnen, R, Szegedi, A, Hiemke, C, Tadic, A

“…Early improvement ( EI ), i.e. a symptom reduction from baseline of at least 20% after 2 weeks, has been proven to be a clinically useful predictor for later…”
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Oxycodone/naloxone prolonged-release has positive quality of life outcomes in patients with severe RLS —/INS; Results of a 1-year study by Kohnen, R, Benes, H, Grote, L, Högl, B, Winkelmann, J, Allen, R.P, Hopp, M, Bosse, B, Trenkwalder, C

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Opioid treatment is effective in patients with severe RLS after failure of previous medications —/INS; Results of a 1-year study by Trenkwalder, C, Benes, H, Grote, L, Högl, B, Winkelmann, J, Allen, R.P, Hopp, M, Bosse, B, Kohnen, R

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Acupuncture and Chinese herbal medicine in the treatment of patients with seasonal allergic rhinitis: a randomized‐controlled clinical trial by Brinkhaus, B., Hummelsberger, J., Kohnen, R., Seufert, J., Hempen, C.‐H., Leonhardy, H., Nögel, R., Joos, S., Hahn, E., Schuppan, D.

“…Background:  Patients with allergic rhinitis (AR) increasingly use complementary medicine. The aim of this study was to determine whether traditional Chinese…”
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A controlled study of additional sr-L-dopa in L-dopa-responsive restless legs syndrome with late-night symptoms by COLLADO-SEIDEL, V, KAZENWADEL, J, WETTER, T. C, KOHNEN, R, WINKELMANN, J, SELZER, R, OERTEL, W. H, TRENKWALDER, C

“…To investigate whether a combination treatment of regular-release levodopa (rr-L-dopa) and sustained-release levodopa (sr-L-dopa) compared with monotherapy of…”
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