Search Results - "R. Green, A."

Pharmacological approaches to acute ischaemic stroke: reperfusion certainly, neuroprotection possibly by Green, A R

“…Stroke is a major cause of both death and disability. However, there are no pharmacological treatments used in most countries other than recombinant tissue…”
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Deglacial Pulse of Neutralized Carbon From the Pacific Seafloor: A Natural Analog for Ocean Alkalinity Enhancement? by Green, R. A., Hain, M. P., Rafter, P. A.

“…The ocean carbon reservoir controls atmospheric carbon dioxide (CO2) on millennial timescales. Radiocarbon (14C) anomalies in eastern North Pacific sediments…”
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The prognostic significance of B lymphocytes in invasive carcinoma of the breast by Mahmoud, S. M. A., Lee, A. H. S., Paish, E. C., Macmillan, R. D., Ellis, I. O., Green, A. R.

“…Although the favourable role of T lymphocyte populations in different tumour types is established, that of B cells is still a matter of debate and needs…”
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Tumour-infiltrating macrophages and clinical outcome in breast cancer by Mahmoud, S M A, Lee, A H S, Paish, E C, Macmillan, R D, Ellis, I O, Green, A R

“…Macrophages constitute a major component of the leucocytic infiltrate of tumours. Human studies show an association between tumour-associated macrophages and…”
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The role of monoamines in the changes in body temperature induced by 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) and its derivatives by Docherty, JR, Green, AR

“…Hyperthermia is probably the most widely known acute adverse event that can follow ingestion of 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) by…”
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Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer by Rakha, E A, Soria, D, Green, A R, Lemetre, C, Powe, D G, Nolan, C C, Garibaldi, J M, Ball, G, Ellis, I O

“…Background: Current management of breast cancer (BC) relies on risk stratification based on well-defined clinicopathologic factors. Global gene expression…”
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BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received by Dawson, S-J, Makretsov, N, Blows, F M, Driver, K E, Provenzano, E, Le Quesne, J, Baglietto, L, Severi, G, Giles, G G, McLean, C A, Callagy, G, Green, A R, Ellis, I, Gelmon, K, Turashvili, G, Leung, S, Aparicio, S, Huntsman, D, Caldas, C, Pharoah, P

“…Background: Breast cancer is heterogeneous and the existing prognostic classifiers are limited in accuracy, leading to unnecessary treatment of numerous women…”
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Effects of NXY‐059 in experimental stroke: an individual animal meta‐analysis by Bath, PMW, Gray, LJ, Bath, AJG, Buchan, A, Miyata, T, Green, AR

“…Background and purpose:  Disodium 2,4‐disulphophenyl‐N‐tert‐butylnitrone (NXY‐059) was neuroprotective in experimental stroke models but ineffective in a large…”
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The OPTIMIZE patient- and family-centered, primary care-based deprescribing intervention for older adults with dementia or mild cognitive impairment and multiple chronic conditions: study protocol for a pragmatic cluster randomized controlled trial by Bayliss, E A, Shetterly, S M, Drace, M L, Norton, J, Green, A R, Reeve, E, Weffald, L A, Wright, L, Maciejewski, M L, Sheehan, O C, Wolff, J L, Gleason, K S, Kraus, C, Maiyani, M, Du Vall, M, Boyd, C M

“…Most individuals with dementia or mild cognitive impairment (MCI) have multiple chronic conditions (MCC). The combination leads to multiple medications and…”
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Addressing limitations in existing ‘simplified’ liquefaction triggering evaluation procedures: application to induced seismicity in the Groningen gas field by Green, R. A., Bommer, J. J., Rodriguez-Marek, A., Maurer, B. W., Stafford, P. J., Edwards, B., Kruiver, P. P., de Lange, G., van Elk, J.

“…The Groningen gas field is one of the largest in the world and has produced over 2000 billion m 3 of natural gas since the start of production in 1963. The…”
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The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis by Roxanis, I, Colling, R, Kartsonaki, C, Green, A R, Rakha, E A

“…As only a minor portion of the information present in histological sections is accessible by eye, recognition and quantification of complex patterns and…”
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Liquefaction Hazard in the Groningen Region of the Netherlands due to Induced Seismicity by Green, R. A, Bommer, J. J, Stafford, P. J, Maurer, B. W, Kruiver, P. P, Edwards, B, Rodriguez-Marek, A, de Lange, G, Oates, S. J, Storck, T, Omidi, P, Bourne, S. J, van Elk, J

“…AbstractThe operator of the Groningen gas field is leading an effort to quantify the seismic hazard and risk of the region due to induced earthquakes,…”
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Patterns of biomarker expression in patients treated with primary endocrine therapy – a unique insight using core needle biopsy tissue microarray by Parks, R. M., Albanghali, M. A., Syed, B. M., Green, A. R., Ellis, I. O., Cheung, K-L.

“…Purpose Prediction of response to primary endocrine therapy (PET) in older women is based on measurement of oestrogen receptor (ER), progesterone receptor…”
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Quantitative pharmacology or pharmacokinetic pharmacodynamic integration should be a vital component in integrative pharmacology by Gabrielsson, J, Green, A R

“…Pharmacodynamics (PD) examines the relationship between drug concentration and onset, intensity, and duration of the pharmacological effect. Pharmacokinetics…”
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Correction to: KSR1 regulates BRCA1 degradation and inhibits breast cancer growth by Stebbing, J., Zhang, H., Xu, Y., Lit, L. C., Green, A. R., Grothey, A., Lombardo, Y., Periyasamy, M., Blighe, K., Zhang, W., Shaw, J. A., Ellis, I. O., Lenz, H. J., Giamas, G.

“…A Correction to this paper has been published: https://doi.org/10.1038/s41388-021-01759-9…”
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The effect of estrogen on brown adipose tissue activity in male rats by Sievers, W, Kettle, C, Green, R A, Van Schaik, L, Hale, M W, Irving, H R, Whelan, D R, Rathner, J A

“…Centrally administered estrogen can increase sympathetic nerve activity to brown adipose tissue, resulting in thermogenesis. The central thermogenic effects of…”
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Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation by Rakha, EA, Putti, TC, Abd El-Rehim, DM, Paish, C, Green, AR, Powe, DG, Lee, AH, Robertson, JF, Ellis, IO

“…The aim of this study was to assess the morphological characteristics and immunohistochemical profile of breast carcinomas with basal and myoepithelial…”
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Performance of conducting polymer electrodes for stimulating neuroprosthetics by Green, R A, Matteucci, P B, Hassarati, R T, Giraud, B, Dodds, C W D, Chen, S, Byrnes-Preston, P J, Suaning, G J, Poole-Warren, L A, Lovell, N H

“…Recent interest in the use of conducting polymers (CPs) for neural stimulation electrodes has been growing; however, concerns remain regarding the stability of…”
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A gene-expression signature to predict survival in breast cancer across independent data sets by NADERI, A, TESCHENDORFF, A. E, CALDAS, C, BARBOSA-MORAIS, N. L, PINDER, S. E, GREEN, A. R, POWE, D. G, ROBERTSON, J. F. R, APARICIO, S, ELLIS, I. O, BRENTON, J. D

“…Prognostic signatures in breast cancer derived from microarray expression profiling have been reported by two independent groups. These signatures, however,…”
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Biology of primary breast cancer in older women treated by surgery: with correlation with long-term clinical outcome and comparison with their younger counterparts by Syed, B M, Green, A R, Paish, E C, Soria, D, Garibaldi, J, Morgan, L, Morgan, D A L, Ellis, I O, Cheung, K L

“…Background: As age advances breast cancer appears to change its biological characteristics, however, very limited data are available to define the precise…”
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