Search Results - "R. G. Goncharov"

Protective role of exogenous recombinant peroxiredoxin 6 under ischemia-reperfusion injury of kidney by Goncharov, R. G., Rogov, K. A., Temnov, A. A., Novoselov, V. I., Sharapov, M. G.

“…Peroxiredoxin 6 (Prx6) is an important antioxidant enzyme with various functions in the cell. Prx6 reduces a wide range of peroxide substrates, playing a…”
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Ischemia–Reperfusion Injury: Molecular Mechanisms of Pathogenesis and Methods of Their Correction by Goncharov, R. G., Sharapov, M. G.

“…—Ischemia–reperfusion is a cascade of complex and interrelated pathological processes underlying many human diseases, including such socially significant…”
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Protective effect of exogenous peroxiredoxin 6 and thymic peptide thymulin on BBB conditions in an experimental model of multiple sclerosis by Lunin, S.M., Novoselova, E.G., Glushkova, O.V., Parfenyuk, S.B., Kuzekova, A.A., Novoselova, T.V., Sharapov, M.G., Mubarakshina, E.K., Goncharov, R.G., Khrenov, M.O.

“…This study aimed to assess the effects of the immunomodulator thymulin, a thymic peptide with anti-inflammatory effects, and peroxiredoxin 6 (Prdx6), an…”
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The Thymic Hormone Thymosin-1α Reduces the Pro-Inflammatory Response of Raw 264.7 Cells Induced by Endotoxin by Novoselova, E. G., Glushkova, O. V., Khrenov, M. O., Lunin, S. M., Sharapov, M. G., Goncharov, R. G., Mubarakshina, E. K., Novoselova, T. V., Parfenyuk, S. B.

“…—The aim of this work was to study the effects of thymosin-1 alpha (Tα1) on the anti-inflammatory response of RAW 264.7 macrophages cultured in the presence of…”
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Geldanamycin Enhances the Radioprotective Effect of Peroxyredoxin 6 in Irradiated 3T3 Fibroblasts by Novoselova, E. G., Glushkova, O. V., Sharapov, M. G., Khrenov, M. O., Parfenyuk, S. B., Lunin, S. M., Novoselova, T. V., Mubarakshina, A. K., Goncharov, R. G., Fesenko, E. E.

“…The aim of the study was to evaluate the possibility of increasing the radioprotective potential of peroxiredoxin 6 (Prdx6) and its mutant form S32A by their…”
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Natural Dicarbonyls Inhibit Peroxidase Activity of Peroxiredoxins by Lankin, V. Z., Sharapov, M. G., Goncharov, R. G., Tikhaze, A. K., Novoselov, V. I.

“…It was established that recombinant human peroxiredoxins (Prx1, Prx2, Prx4, and Prx6) inhibit natural dicarbonyls formed during free radical peroxidation of…”
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Use of peroxiredoxin for preconditioning of heterotopic heart transplantation in a rat by N. V. Grudinin, V. K. Bogdanov, M. G. Sharapov, N. S. Bunenkov, N. P. Mozheiko, R. G. Goncharov, E. E. Fesenko, V. I. Novoselov

“…Peroxiredoxin 6 (Prdx6) is an antioxidant enzyme in the human body that performs a number of important functions in the cell. Prdx6 restores a wide range of…”
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Enzymatic antioxidant system of endotheliocytes by Sharapov, M. G., Goncharov, R. G., Gordeeva, A. E., Novoselov, V. I., Antonova, O. A., Tikhaze, A. K., Lankin, V. Z.

“…It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the “classic” antioxidant enzymes (Cu,Zn-superoxide…”
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Peroxiredoxin 6 Prevents Reperfusion Injury to Isolated Rat Kidney by Gordeeva, A. E., Sharapov, M. G., Goncharov, R. G., Novoselov, V. I.

“…Ischemia-reperfusion (I-R) injury causes a reduction in the viability of donor organs during long-term conservation. In the present study, an antioxidant…”
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The Protective Effect of a Chimeric PSH Antioxidant Enzyme in Renal Ischemia–Reperfusion Injury by Goncharov, R. G., Filkov, G. I., Trofimenko, A. V., Boyarintsev, V. V., Novoselov, V. I., Sharapov, M. G.

“…—A rapid increase in the concentration of free radicals and reactive oxygen species at the reperfusion stage is the most dangerous stage of…”
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The Effect of Exogenous Peroxiredoxin 6 on the State of Mesenteric Vessels and the Small Intestine in Ischemia–Reperfusion Injury by Sharapov, M. G., Gordeeva, A. E., Goncharov, R. G., Tikhonova, I. V., Ravin, V. K., Temnov, A. A., Fesenko, E. E., Novoselov, V. I.

“…Oxidative stress is the main component of pathogenesis in ischemia–reperfusion injury. The administration of exogenous antioxidants suppresses oxidative stress…”
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The Role of Intermolecular Disulfide Bonds in Stabilizing the Structure of Peroxiredoxins by Sharapov, M. G., Penkov, N. V., Gudkov, S. V., Goncharov, R. G., Novoselov, V. I., Fesenko, E. E.

“…The comparative characterization of thermal stability of human peroxiredoxins 1–6 (Prx1–Prx6) has been performed by physicochemical and biochemical methods and…”
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Expression of caspase-3 and the cytokine level in experimental reperfusion syndrome upon treatment with peroxiredoxin 6 by Kubyshkin, A. V., Novosyolov, S. V., Fomochkina, I. I., Kharchenko, V. Z., Pisarev, A. A., Gordeeva, A. E., Beketov, A. A., Kochkina, A. V., Fedosov, M. I., Anisimova, L. V., Goncharov, R. G.

“…Ischemia-reperfusion injury is a significant problem; there is a need for interpretation of its pathogenetic mechanism and a search for potential methods of…”
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