Search Results - "R. Franco"

Mouse Models of Acute Lung Injury and ARDS by D'Alessio, Franco R

“…The acute respiratory distress syndrome (ARDS) is a devastating illness characterized by severe hypoxemia and diffuse alveolar damage. Direct lung infection is…”
Get more information

Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018 by Franco, José R, Cecchi, Giuliano, Priotto, Gerardo, Paone, Massimo, Diarra, Abdoulaye, Grout, Lise, Simarro, Pere P, Zhao, Weining, Argaw, Daniel

“…In 2012 human African trypanosomiasis (HAT), also known as sleeping sickness, was targeted for elimination as a public health problem, set to be achieved by…”
Get full text

Apoptosis and glutathione: beyond an antioxidant by Franco, R, Cidlowski, J A

“…Apoptosis is a conserved homeostatic process critical for organ and tissue morphogenesis, development, and senescence. This form of programmed cell death also…”
Get full text

Diverse macrophage populations mediate acute lung inflammation and resolution by Aggarwal, Neil R, King, Landon S, D'Alessio, Franco R

“…Acute respiratory distress syndrome (ARDS) is a devastating disease with distinct pathological stages. Fundamental to ARDS is the acute onset of lung…”
Get more information

Necroptosis in the Pathophysiology of Disease by Khoury, Mitri K., Gupta, Kartik, Franco, Sarah R., Liu, Bo

“…Over the past 15 years, elegant studies have demonstrated that in certain conditions, programed cell death resembles necrosis and depends on a unique molecular…”
Get full text

The elimination of human African trypanosomiasis: Achievements in relation to WHO road map targets for 2020 by Franco, Jose R, Cecchi, Giuliano, Paone, Massimo, Diarra, Abdoulaye, Grout, Lise, Kadima Ebeja, Augustin, Simarro, Pere P, Zhao, Weining, Argaw, Daniel

“…In the 20th century, epidemics of human African trypanosomiasis (HAT) ravaged communities in a number of African countries. The latest surge in disease…”
Get full text

Reparative T lymphocytes in organ injury by D'Alessio, Franco R, Kurzhagen, Johanna T, Rabb, Hamid

“…Acute organ injuries such as acute cerebrovascular accidents, myocardial infarction, acute kidney injury, acute lung injury, and others are among the leading…”
Get full text

COVID-19 and myeloid cells: complex interplay correlates with lung severity by D'Alessio, Franco R, Heller, Nicola M

“…COVID-19 spans a wide range of symptoms, sometimes with profound immune system involvement. How immune cell subsets change during the disease course and with…”
Get full text

Monitoring the elimination of human African trypanosomiasis: Update to 2016 by Franco, José R, Cecchi, Giuliano, Priotto, Gerardo, Paone, Massimo, Diarra, Abdoulaye, Grout, Lise, Simarro, Pere P, Zhao, Weining, Argaw, Daniel

“…Human African trypanosomiasis (HAT) is a neglected tropical disease targeted for elimination 'as a public health problem' by 2020. The indicators to monitor…”
Get full text

The Transcriptional Signature in Alveolar Macrophages Dictates Acute Respiratory Distress Outcomes by Tejwani, Vickram, D'Alessio, Franco R

“…[...]it reinforces the need to better phenotype patients with ARDS. [...]macrophage transcriptional profiles require confirmation by protein expression and…”
Get full text

Lean Mass Abnormalities in Heart Failure: The Role of Sarcopenia, Sarcopenic Obesity, and Cachexia by Carbone, Salvatore, Billingsley, Hayley E., Rodriguez-Miguelez, Paula, Kirkman, Danielle L., Garten, Ryan, Franco, R. Lee, Lee, Duck-chul, Lavie, Carl J.

“…The role of body composition in patients with heart failure (HF) has been receiving much attention in the last few years. Particularly, reduced lean mass (LM),…”
Get full text

Metabolic programs define dysfunctional immune responses in severe COVID-19 patients by Thompson, Elizabeth A., Cascino, Katherine, Ordonez, Alvaro A., Zhou, Weiqiang, Vaghasia, Ajay, Hamacher-Brady, Anne, Brady, Nathan R., Sun, Im-Hong, Wang, Rulin, Rosenberg, Avi Z., Delannoy, Michael, Rothman, Richard, Fenstermacher, Katherine, Sauer, Lauren, Shaw-Saliba, Kathyrn, Bloch, Evan M., Redd, Andrew D., Tobian, Aaron A.R., Horton, Maureen, Smith, Kellie, Pekosz, Andrew, D’Alessio, Franco R., Yegnasubramanian, Srinivasan, Ji, Hongkai, Cox, Andrea L., Powell, Jonathan D.

“…It is unclear why some SARS-CoV-2 patients readily resolve infection while others develop severe disease. By interrogating metabolic programs of immune cells…”
Get full text

Non-markovian effects on the dynamics of entanglement by Bellomo, B, Lo Franco, R, Compagno, G

“…A procedure that allows us to obtain the dynamics of N independent bodies each locally interacting with its own reservoir is presented. It relies on the…”
Get full text

Regulatory T Cells for Treating Patients With COVID-19 and Acute Respiratory Distress Syndrome: Two Case Reports by Gladstone, Douglas E, Kim, Bo Soo, Mooney, Kathy, Karaba, Andrew H, D'Alessio, Franco R

“…The study on the outcomes in two patients with COVID-19 and acute respiratory distress syndrome (ARDS) who were treated with T regulatory cells (Tregs)…”
Get full text

Older people's perspectives on participation in physical activity: a systematic review and thematic synthesis of qualitative literature by Franco, Marcia R, Tong, Allison, Howard, Kirsten, Sherrington, Catherine, Ferreira, Paulo H, Pinto, Rafael Z, Ferreira, Manuela L

“…Physical inactivity accounts for 9% of all deaths worldwide and is among the top 10 risk factors for global disease burden. Nearly half of people aged over 60…”
Get more information

Reactive oxygen species generated in chloroplasts contribute to tobacco leaf infection by the necrotrophic fungus Botrytis cinerea by Rossi, Franco R., Krapp, Adriana R., Bisaro, Fabiana, Maiale, Santiago J., Pieckenstain, Fernando L., Carrillo, Néstor

“…Summary Reactive oxygen species (ROS) play fundamental roles in plant responses to pathogen infection, including modulation of cell death processes and…”
Get full text

HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation by Brune, Kieran A, Ferreira, Fernanda, Mandke, Pooja, Chau, Eric, Aggarwal, Neil R, D'Alessio, Franco R, Lambert, Allison A, Kirk, Gregory, Blankson, Joel, Drummond, M Bradley, Tsibris, Athe M, Sidhaye, Venkataramana K

“…Several clinical studies show that individuals with HIV are at an increased risk for worsened lung function and for the development of COPD, although the…”
Get full text

Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8–Akt–Slug pathway by Visciano, C, Liotti, F, Prevete, N, Cali', G, Franco, R, Collina, F, de Paulis, A, Marone, G, Santoro, M, Melillo, R M

“…There is increasing evidence that mast cells (MCs) and their mediators are involved in the remodeling of the tumor microenvironment and promote tumor growth,…”
Get full text

Estimating and mapping the population at risk of sleeping sickness by Simarro, Pere P, Cecchi, Giuliano, Franco, José R, Paone, Massimo, Diarra, Abdoulaye, Ruiz-Postigo, José Antonio, Fèvre, Eric M, Mattioli, Raffaele C, Jannin, Jean G

“…Human African trypanosomiasis (HAT), also known as sleeping sickness, persists as a public health problem in several sub-Saharan countries. Evidence-based,…”
Get full text

CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury by D'Alessio, Franco R, Tsushima, Kenji, Aggarwal, Neil R, West, Erin E, Willett, Matthew H, Britos, Martin F, Pipeling, Matthew R, Brower, Roy G, Tuder, Rubin M, McDyer, John F, King, Landon S

“…Acute lung injury (ALI) is characterized by rapid alveolar injury, inflammation, cytokine induction, and neutrophil accumulation. Although early events in the…”
Get full text