Search Results - "R. Dainty, Jack"

IL-6 Signaling Regulates Small Intestinal Crypt Homeostasis by Jeffery, Victoria, Goldson, Andrew J, Dainty, Jack R, Chieppa, Marcello, Sobolewski, Anastasia

“…Gut homeostasis is a tightly regulated process requiring finely tuned complex interactions between different cell types, growth factors, or cytokines and their…”
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Absorption, metabolism and excretion of flavanones from single portions of orange fruit and juice and effects of anthropometric variables and contraceptive pill use on flavanone excretion by Brett, Gary M., Hollands, Wendy, Needs, Paul W., Teucher, Birgit, R. Dainty, Jack, Davis, Barry D., Brodbelt, Jennifer S., Kroon, Paul A.

“…Oranges are rich sources of flavonoids that are bioactive and may protect against age-related diseases. The absorption of orange flavanones may be affected by…”
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Folic acid handling by the human gut: implications for food fortification and supplementation by Patanwala, Imran, King, Maria J, Barrett, David A, Rose, John, Jackson, Ralph, Hudson, Mark, Philo, Mark, Dainty, Jack R, Wright, Anthony JA, Finglas, Paul M, Jones, David E

“…Background: Current thinking, which is based mainly on rodent studies, is that physiologic doses of folic acid (pterylmonoglutamic acid), such as dietary…”
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Impact of COVID-19 pandemic social restriction measures on people with rheumatic and musculoskeletal diseases in the UK: a mixed-methods study by Smith, Toby O, Belderson, Pippa, Dainty, Jack R, Birt, Linda, Durrant, Karen, Chipping, Jacqueline R, Tsigarides, Jordan, Yates, Max, Naughton, Felix, Werry, Sarah, Notley, Caitlin, Shepstone, Lee, MacGregor, Alex J

“…ObjectivesTo determine the impact of COVID-19 pandemic social restriction measures on people with rheumatic and musculoskeletal diseases (RMDs) and to explore…”
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Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK by Wright, Anthony J. A., Dainty, Jack R., Finglas, Paul M.

“…Following an introduction of the importance of folates and the rationale for seeking to estimate fractional folate absorption from foods (especially for…”
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Estimation of dietary iron bioavailability from food iron intake and iron status by Dainty, Jack R, Berry, Rachel, Lynch, Sean R, Harvey, Linda J, Fairweather-Tait, Susan J

“…Currently there are no satisfactory methods for estimating dietary iron absorption (bioavailability) at a population level, but this is essential for deriving…”
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Adolescent time use and mental health: a cross-sectional, compositional analysis in the Millennium Cohort Study by Atkin, Andrew J, Dainty, Jack R, Dumuid, Dorothea, Kontostoli, Elli, Shepstone, Lee, Tyler, Richard, Noonan, Robert, Richardson, Cassandra, Fairclough, Stuart J

“…ObjectiveTo examine the association of 24-hour time-use compositions with mental health in a large, geographically diverse sample of UK…”
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One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses in Healthy Elderly Subjects: Results From the United Kingdom Arm of the NU-AGE Trial by Maijo, Monica, Ivory, Kamal, Clements, Sarah J, Dainty, Jack R, Jennings, Amy, Gillings, Rachel, Fairweather-Tait, Susan, Gulisano, Massimo, Santoro, Aurelia, Franceschi, Claudio, Carding, Simon R, Nicoletti, Claudio

“…Amongst the major features of aging are chronic low grade inflammation and a decline in immune function. The Mediterranean diet (MedDiet) is considered to be a…”
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Plasma hepcidin concentrations significantly predict interindividual variation in iron absorption in healthy men by ROE, Mark A, COLLINGS, Rachel, DAINTY, Jack R, SWINKELS, Dorine W, FAIRWEATHER-TAIT, Susan J

“…Iron absorption is proposed to be regulated by circulating hepcidin, but, to date, little data are available to evaluate this relation in humans. Stored…”
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Sodium and Bone Health: Impact of Moderately High and Low Salt Intakes on Calcium Metabolism in Postmenopausal Women by Teucher, Birgit, Dainty, Jack R, Spinks, Caroline A, Majsak‐Newman, Gosia, Berry, David J, Hoogewerff, Jurian A, Foxall, Robert J, Jakobsen, Jette, Cashman, Kevin D, Flynn, Albert, Fairweather‐Tait, Susan J

“…High salt intake is a well‐recognized risk factor for osteoporosis because it induces calciuria, but the effects of salt on calcium metabolism and the…”
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Oral delivery of a probiotic induced changes at the nasal mucosa of seasonal allergic rhinitis subjects after local allergen challenge: a randomised clinical trial by Ivory, Kamal, Wilson, Andrew M, Sankaran, Prasanna, Westwood, Marta, McCarville, Justin, Brockwell, Claire, Clark, Allan, Dainty, Jack R, Zuidmeer-Jongejan, Laurian, Nicoletti, Claudio

“…To determine effects of probiotic consumption on clinical and immunological parameters of seasonal allergic rhinitis (SAR) in an out-of-season single nasal…”
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Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa by Belshaw, Nigel J., Pal, Nandita, Tapp, Henri S., Dainty, Jack R., Lewis, Michael P.N., Williams, Mark R., Lund, Elizabeth K., Johnson, Ian T.

“…Methylation of CpG islands (CGIs) in the promoter regions of tumour suppressor genes is common in colorectal cancer and occurs also in an age-dependent manner…”
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Alginate inhibits iron absorption from ferrous gluconate in a randomized controlled trial and reduces iron uptake into Caco-2 cells by Wawer, Anna A, Harvey, Linda J, Dainty, Jack R, Perez-Moral, Natalia, Sharp, Paul, Fairweather-Tait, Susan J

“…Previous in vitro results indicated that alginate beads might be a useful vehicle for food iron fortification. A human study was undertaken to test the…”
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Impact of menstrual blood loss and diet on iron deficiency among women in the UK by Harvey, Linda J., Armah, Charlotte N., Dainty, Jack R., Foxall, Robert J., Lewis, D. John, Langford, Nicola J., Fairweather-Tait, Susan J.

“…Women of childbearing age are at risk of Fe deficiency if insufficient dietary Fe is available to replace menstrual and other Fe losses. Haem Fe represents…”
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Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial by Goldson, Andrew J, Fairweather-Tait, Susan J, Armah, Charlotte N, Bao, Yongping, Broadley, Martin R, Dainty, Jack R, Furniss, Caroline, Hart, David J, Teucher, Birgit, Hurst, Rachel

“…The uncertainty surrounding dietary requirements for selenium (Se) is partly due to limitations in biomarkers of Se status that are related to health outcomes…”
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The use of BeWo cells as an in vitro model for placental iron transport by Heaton, Sarah J, Eady, John J, Parker, Mary L, Gotts, Kathryn L, Dainty, Jack R, Fairweather-Tait, Susan J, McArdle, Harry J, Srai, Kaila S, Elliott, Ruan M

“…BeWo cells are a placental cell line that has been widely used as an in vitro model for the placenta. The b30 subclone of these cells can be grown on permeable…”
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Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults by Ivory, Kamal, Prieto, Elena, Spinks, Caroline, Armah, Charlotte N, Goldson, Andrew J, Dainty, Jack R, Nicoletti, Claudio

“…Summary Background & aims Mortality resulting from influenza (flu) virus infections occurs primarily in the elderly through declining immunity. Studies in mice…”
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Cross-sectional associations between 24-hour activity behaviours and mental health indicators in children and adolescents: A compositional data analysis by Fairclough, Stuart J., Tyler, Richard, Dainty, Jack R., Dumuid, Dorothea, Richardson, Cassandra, Shepstone, Lee, Atkin, Andrew J.

“…We examined associations between youth 24-hour activity behaviour compositions and mental health. Data were collected from 359 participants (aged 9-13 years)…”
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Fish consumption and markers of colorectal cancer risk: a multicenter randomized controlled trial by Pot, Gerda K, Majsak-Newman, Gosia, Geelen, Anouk, Harvey, Linda J, Nagengast, Fokko M, Witteman, Ben JM, van de Meeberg, Paul C, Timmer, Robin, Tan, Adriaan, Wahab, Peter J, Hart, Andrew R, Williams, Matthew P, Przybylska-Phillips, Kasia, Dainty, Jack R, Schaafsma, Gertjan, Kampman, Ellen, Lund, Elizabeth K

“…BACKGROUND: Diet is a major factor in the etiology of colorectal cancer, with high fish consumption possibly decreasing colorectal cancer risk, as was shown in…”
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Bioavailability of Glucoraphanin and Sulforaphane from High‐Glucoraphanin Broccoli by Sivapalan, Tharsini, Melchini, Antonietta, Saha, Shikha, Needs, Paul W., Traka, Maria H., Tapp, Henri, Dainty, Jack R., Mithen, Richard F.

“…Scope Broccoli accumulates 4‐methylsulphinylbutyl glucosinolate (glucoraphanin) which is hydrolyzed to the isothiocyanate sulforaphane. Through the…”
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