Search Results - "R. Bilyy"
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Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines
Published in Nature medicine (01-05-2014)“…Neutrophil extracellular traps (NETs) are released by neutrophils in response to infection and have also been observed in sterile inflammation. Here,…”
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2
Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease
Published in Organic & biomolecular chemistry (28-04-2016)“…The anti-adhesive strategy, consisting of disrupting bacterial attachment to the host cells, is widely explored as an alternative to antibiotic therapies…”
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3
Sweet but dangerous – the role of immunoglobulin G glycosylation in autoimmunity and inflammation
Published in Lupus (01-07-2016)“…Glycosylation is well-known to modulate the functional capabilities of immunoglobulin G (IgG)-mediated cellular and humoral responses. Indeed, highly…”
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Neutrophil activation at high-fat high-cholesterol and high-fructose diets induces low-grade inflammation in mice
Published in Ukrainian biochemical journal (25-04-2024)“…Nonalcoholic fatty liver disease (NAFLD), which can progress to nonalcoholic steatohepatitis (NASH), is a significant health concern affecting a substantial…”
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Altered glycan accessibility on native immunoglobulin G complexes in early rheumatoid arthritis and its changes during therapy
Published in Clinical and experimental immunology (01-09-2017)“…Summary The goal of this study was to investigate the glycosylation profile of native immunoglobulin (Ig)G present in serum immune complexes in patients with…”
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Neutrophil-released enzymes can influence composition of circulating immune complexes in multiple sclerosis
Published in Autoimmunity (Chur, Switzerland) (18-08-2018)“…During NET formation, the content of neutrophils granules is released into the intercellular milieu. Consisting of many proteases and ROS species, formed NETs…”
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Altered glycosylation of complexed native IgG molecules is associated with disease activity of systemic lupus erythematosus
Published in Lupus (01-05-2015)“…In addition to the redundancy of the receptors for the Fc portion of immunoglobulins, glycans result in potential ligands for a plethora of lectin receptors…”
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A blast without power – cell death induced by the tuberculosis-necrotizing toxin fails to elicit adequate immune responses
Published in Cell death and differentiation (01-06-2016)“…In this study, we deploy a doxycycline-dependent suicide switch integrated in a tumor challenge model. With this experimental setup, we characterized the…”
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Glycosylation of random IgG distinguishes seropositive and seronegative rheumatoid arthritis
Published in Autoimmunity (Chur, Switzerland) (01-05-2018)“…The N-glycosylation of human immunoglobulins, especially IgGs, plays a critical role in determining affinity of IgGs towards their effector (pro- and…”
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10
Sialylation of anti‐histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells
Published in Clinical and experimental immunology (01-04-2016)“…Summary The Fc portion of immunoglobulin (Ig)G harbours a single glycosylation site. Glycan sialylation is critical for structure and for certain effector…”
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11
Freezing influences, the exposure of IgG glycans in sera from multiple sclerosis patients
Published in Ukrainian biochemical journal (17-04-2020)“…N-glycan residues attached to Asn297 of the immunoglobulin IgG molecule are responsible for changing its structural conformation and are used as markers of…”
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12
Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitate their clearance by human macrophages
Published in Clinical and experimental immunology (01-01-2015)“…Summary Recently we reported the first known incidence of antibodies possessing catalytic sialidase activity (sialidase abzymes) in the serum of patients with…”
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13
Water-soluble pristine fullerenes C60 increase the specific conductivity and capacity of lipid model membrane and form the channels in cellular plasma membrane
Published in Journal of biomedical nanotechnology (01-06-2012)“…The aim of the present work was the investigation of the interaction of water-soluble pristine fullerenes C60 with bimolecular lipid model membrane (BLM) and…”
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14
Novel approach for discrimination of eosinophilic granulocytes and evaluation of their surface receptors in a multicolor fluorescent histological assessment
Published in Ukrainian biochemical journal (25-04-2020)“…Eosinophilic granulocytes mediate immune responses against multicellular parasites and are also the main contributor to such pathological conditions as allergy…”
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15
Analysis of chitosan molecular weight profile by electrophoresis in a porosity step gradient polyacrylamide gel
Published in Ukrainian biochemical journal (11-07-2022)“…Chitosan is biocompatible and biodegradable natural biopolymer widely applied in various fields of biology, medicine, and pharmacy, however, its effects…”
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16
Magnetic separation of apoptotic cells with lectin-conjugated microparticles
Published in Materialwissenschaft und Werkstofftechnik (01-03-2016)“…Both phosphatidylserine (PS) and oligomannose/desialylated glycans are known to be exposed on the surface of dying cells and used by macrophages to endure…”
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Sweet taste of cell death: role of carbohydrate recognition systems
Published in Ukrainian biochemical journal (27-12-2013)“…This paper describes a complicated way how the glycoepitops’ alterations on a surface of dying cells allow investigators to decipher specific mechanisms…”
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18
A brief account of Julius Planer's life and research
Published in Condensed matter physics (01-01-2010)“…A brief account of the life and research activities of Julius Planer is presented. Professor Planer is a scientist who lived one and half century ago. However,…”
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Lectinocytochemical detection of apoptotic murine leukemia L1210 cells
Published in Cytometry. Part A (01-12-2003)“…Background Various cytomorphologic and biochemical markers of apoptosis are found in different compartments (plasma membrane, cytoplasm, nucleus, and…”
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Utilization of GaN:Eu3+ nanocrystals for the detection of programmed cell death
Published in Physica. E, Low-dimensional systems & nanostructures (01-04-2008)Get full text
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