Search Results - "R M Epand"

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy by Kagan, V E, Jiang, J, Huang, Z, Tyurina, Y Y, Desbourdes, C, Cottet-Rousselle, C, Dar, H H, Verma, M, Tyurin, V A, Kapralov, A A, Cheikhi, A, Mao, G, Stolz, D, St. Croix, C M, Watkins, S, Shen, Z, Li, Y, Greenberg, M L, Tokarska-Schlattner, M, Boissan, M, Lacombe, M-L, Epand, R M, Chu, C T, Mallampalli, R K, Bayır, H, Schlattner, U

“…Mitophagy is critical for cell homeostasis. Externalization of the inner mitochondrial membrane phospholipid, cardiolipin (CL), to the surface of the outer…”
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Membrane-Active Peptides and the Clustering of Anionic Lipids by Wadhwani, P., Epand, R.F., Heidenreich, N., Bürck, J., Ulrich, A.S., Epand, R.M.

“…There is some overlap in the biological activities of cell-penetrating peptides (CPPs) and antimicrobial peptides (AMPs). We compared nine AMPs, seven CPPs,…”
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PAMAM dendrimers and model membranes: Differential scanning calorimetry studies by Klajnert, B., Epand, R.M.

“…Dendrimers attract much attention as potential drug and gene carriers for intracellular delivery. From this point of view, it is crucial to extend our…”
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Detection of submicron-sized raft-like domains in membranes by small-angle neutron scattering by PENCER, J, MILLS, T, ANGHEL, V, KRUEGER, S, EPAND, R. M, KATSARAS, J

“…Using coarse grained models of heterogeneous vesicles we demonstrate the potential for small-angle neutron scattering (SANS) to detect and distinguish between…”
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Physical Properties Affecting Cochleate Formation and Morphology Using Antimicrobial Oligo-acyl-lysyl Peptide Mimetics and Mixtures Mimicking the Composition of Bacterial Membranes in the Absence of Divalent Cations by Epand, R. F, Sarig, H, Ohana, D, Papahadjopoulos-Sternberg, B, Mor, A, Epand, R. M

“…Several cationic antimicrobial oligo-acyl-lysyl (OAK) peptide mimetics can form cochleate structures, that is, elongated multilayered cylindrical structures,…”
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The mechanism of lamellar-to-inverted hexagonal phase transitions in phosphatidylethanolamine: implications for membrane fusion mechanisms by Siegel, D.P., Epand, R.M.

“…We studied the mechanism of the lamellar-to-inverted hexagonal (L alpha/H[II]) phase transition, using time-resolved cryotransmission electron microscopy…”
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Relationship of Membrane Curvature to the Formation of Pores by Magainin 2 by Matsuzaki, Katsumi, Sugishita, Ken-ichi, Ishibe, Noriko, Ueha, Mayu, Nakata, Saori, Miyajima, Koichiro, Epand, Richard M

“…Magainin 2, an antimicrobial peptide from the Xenopus skin, kills bacteria by permeabilizing the cell membranes. We have proposed that the peptide…”
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Lipopeptaibols, a novel family of membrane active, antimicrobial peptides by Toniolo, C, Crisma, M, Formaggio, F, Peggion, C, Epand, R F, Epand, R M

“…Lipopeptaibols are members of a novel group of naturally occurring, short peptides with antimicrobial activity, characterized by a lipophilic acyl chain at the…”
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Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide by Datta, G, Chaddha, M, Hama, S, Navab, M, Fogelman, A M, Garber, D W, Mishra, V K, Epand, R M, Epand, R F, Lund-Katz, S, Phillips, M C, Segrest, J P, Anantharamaiah, G M

“…We have recently shown that a class A amphipathic peptide 5F with increased amphipathicity protected mice from diet-induced atherosclerosis (Garber et al. J…”
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Structural Study of the Relationship between the Rate of Membrane Fusion and the Ability of the Fusion Peptide of Influenza Virus To Perturb Bilayers by Colotto, A, Epand, R. M

“…The amino-terminal segment of the HA2 protein of influenza virus (fusion peptide) has been identified as an important region for membrane fusion. The wild type…”
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Membrane lipid composition and the interaction of pardaxin: the role of cholesterol by Epand, R F, Ramamoorthy, A, Epand, R M

“…Modulation by pardaxin of the phase transitions of dimyristoyl phosphatidylcholine, 1-stearoyl-2-oleoyl phosphatidylcholine or 1-stearoyl-2-oleoyl…”
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Regulation of CTP:  Phosphocholine Cytidylyltransferase Activity by the Physical Properties of Lipid Membranes:  An Important Role for Stored Curvature Strain Energy by Davies, Sarah M. A, Epand, Richard M, Kraayenhof, Ruud, Cornell, Rosemary B

“…CTP:Phosphocholine cytidylyltransferase (CT) catalyzes the key step in phosphatidylcholine (PC) synthesis. CT is activated by binding to certain lipid…”
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Effect of influenza hemagglutinin fusion peptide on lamellar/inverted phase transitions in dipalmitoleoylphosphatidylethanolamine: implications for membrane fusion mechanisms by Siegel, D.P., Epand, R.M.

“…Low mole fractions of viral fusion peptides induce inverted cubic (Q II) phases in dipalmitoleoylphosphatidylethanolamine (DiPoPE), a lipid with unsaturated…”
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A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac, and smooth muscle cells by Mughal, W, Nguyen, L, Pustylnik, S, da Silva Rosa, S C, Piotrowski, S, Chapman, D, Du, M, Alli, N S, Grigull, J, Halayko, A J, Aliani, M, Topham, M K, Epand, R M, Hatch, G M, Pereira, T J, Kereliuk, S, McDermott, J C, Rampitsch, C, Dolinsky, V W, Gordon, J W

“…Exposure to metabolic disease during fetal development alters cellular differentiation and perturbs metabolic homeostasis, but the underlying molecular…”
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Protein-Induced Formation of Cholesterol-Rich Domains by Epand, Richard M, Maekawa, Shohei, Yip, Christopher M, Epand, Raquel F

“…A major protein of neuronal rafts, NAP-22, binds specifically to cholesterol. We demonstrate by circular dichroism that NAP-22 contains a significant amount of…”
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Structural Study of the Interaction between the SIV Fusion Peptide and Model Membranes by Colotto, A, Martin, I, Ruysschaert, J.-M, Sen, A, Hui, S. W, Epand, R. M

“…It has been shown that there is a correlation between the fusogenecity of synthetic peptides corresponding to the N-terminal segment of wild-type and mutant…”
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Diversity of antimicrobial peptides and their mechanisms of action by Epand, Richard M., Vogel, Hans J.

“…Antimicrobial peptides encompass a wide variety of structural motifs. Many peptides have α-helical structures. The majority of these peptides are cationic and…”
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Anomalous swelling in phospholipid bilayers is not coupled to the formation of a ripple phase by Mason, P C, Nagle, J F, Epand, R M, Katsaras, J

“…Aligned stacks of monomethyl and dimethyl dimyristoyl phosphatidylethanolamine (DMPE) lipid bilayers, like the much studied dimyristoyl PC (DMPC) bilayers,…”
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Effect of cationic cholesterol derivatives on gene transfer and protein kinase C activity by Farhood, H, Bottega, R, Epand, R M, Huang, L

“…Four different cationic derivatives of cholesterol were synthesized which contain either a tertiary or a quaternary amino head group, with and without a…”
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Physiological Implications of the Contrasting Modulation of the Activities of the ε- and ζ-Isoforms of Diacylglycerol Kinase by Thirugnanam, Subarna, Topham, Matthew K, Epand, Richard M

“…We have shown that the requirement of the ε-isoform of diacylglycerol kinase for diacylglycerols containing arachidonic acid is specific for this substrate and…”
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