Search Results - "R B Johnston, Jr"

S-thiolation of glyceraldehyde-3-phosphate dehydrogenase induced by the phagocytosis-associated respiratory burst in blood monocytes by V Ravichandran, T Seres, T Moriguchi, J A Thomas, R B Johnston, Jr

“…Chemical oxidants can induce the covalent binding of low molecular weight thiols to reactive sulfhydryls on proteins (S-thiolation). We found that stimulation…”
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Reduced neutrophil superoxide anion release after prolonged infusions of lidocaine by Peck, S L, Johnston, Jr, R B, Horwitz, L D

“…Lidocaine is used extensively in coronary care units, yet the effect of lidocaine infusions on neutrophil function has not been known. Lidocaine and other…”
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Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide by Haslett, C, Guthrie, LA, Kopaniak, MM, Johnston, RB, Jr, Henson, PM

“…Human neutrophils were isolated from peripheral blood by four methods: 1) Ficoll-Hypaque gradients and erythrocyte lysis, 2) plasma-Percoll gradients, 3) a…”
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Protein S-thiolation and dethiolation during the respiratory burst in human monocytes. A reversible post-translational modification with potential for buffering the effects of oxidant stress by Seres, T, Ravichandran, V, Moriguchi, T, Rokutan, K, Thomas, JA, Johnston, RB, Jr

“…Stimulation of the respiratory burst in mouse macrophages or human neutrophils results in the formation of disulfide bonds between low m.w. thiols and…”
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Candidacidal mechanisms in the human neonate. Impaired IFN-gamma activation of macrophages in newborn infants by Marodi, L, Kaposzta, R, Campbell, DE, Polin, RA, Csongor, J, Johnston, RB, Jr

“…We studied the interaction between Candida albicans and mononuclear phagocytes derived from cord blood. In the presence of normal serum, the extent of…”
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Neutrophil-mediated injury to endothelial cells: enhancement by endotoxin and essential role of neutrophil elastase by SMEDLY, L. A, TONNESEN, M. G, SANDHAUS, R. A, HASLETT, C, GUTHRIE, L. A, JOHNSTON, R. B. JR, HENSON, P. M, WORTHEN, G. S

“…The neutrophil has been implicated as an important mediator of vascular injury, especially after endotoxemia. This study examines neutrophil-mediated injury to…”
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Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocyte-derived macrophages by Marodi, L, Korchak, HM, Johnston, RB, Jr

“…We studied the biochemical basis of phagocytosis of Candida albicans, a serious pathogen, and Candida parapsilosis, which is rarely pathogenic, by human…”
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Activation of the respiratory burst in macrophages. Phosphorylation specifically associated with Fc receptor-mediated stimulation by Brozna, JP, Hauff, NF, Phillips, WA, Johnston, RB, Jr

“…Inflammatory macrophages elicited from the peritoneal cavity of mice injected with endotoxin can avidly ingest E opsonized with IgG antibody (EIgG) or with IgM…”
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Evidence for participation of vicinal dithiols in the activation sequence of the respiratory burst of human neutrophils by KUTSUMI, H, KAWAI, K, JOHNSTON, R. B, ROKUTAN, K

“…Phenylarsine oxide (PAO) specifically forms a stable ring complex with vicinal dithiols that can be reversed with 2,3-dimercaptopropanol (DMP). Pretreatment of…”
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Relationship between membrane potential changes and superoxide- releasing capacity in resident and activated mouse peritoneal macrophages by Kitagawa, S, Johnston, RB, Jr

“…In an attempt to understand better the molecular basis for the enhanced respiratory burst of activated macrophages (M phi), we investigated the relationship…”
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Oxidative metabolism in cord blood monocytes and monocyte-derived macrophages by SPEER, C. P, AMBRUSO, D. R, GRIMSLEY, J, JOHNSTON, R. B. JR

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Enhanced release of oxygen metabolites by monocyte-derived macrophages exposed to proteolytic enzymes: activity of neutrophil elastase and cathepsin G by Speer, CP, Pabst, MJ, Hedegaard, HB, Rest, RF, Johnston, RB, Jr

“…Macrophages at sites of inflammation are exposed to proteolytic enzymes derived from neutrophils, platelets, clotting factors, complement, and damaged tissues…”
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Zymosan-stimulated production of phosphatidic acid by macrophages: relationship to release of superoxide anion and inhibition by agents that increase intracellular cyclic AMP by Channon, J Y, Leslie, C C, Johnston, Jr, R B

“…Murine peritoneal macrophages (m phi) respond to unopsonized zymosan with the production of superoxide anion (O2-). We investigated the involvement of…”
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Deactivation of the respiratory burst in activated macrophages: evidence for alteration of signal transduction by Kitagawa, S, Johnston, RB, Jr

“…Enhanced function of the respiratory burst, measured as stimulated release of superoxide anion (O2-) or hydrogen peroxide, characterizes activated macrophages…”
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The priming of neutrophils by lipopolysaccharide for production of intracellular platelet-activating factor. Potential role in mediation of enhanced superoxide secretion by Worthen, GS, Seccombe, JF, Clay, KL, Guthrie, LA, Johnston, RB, Jr

“…LPS priming of the neutrophil results in enhanced release of superoxide upon subsequent stimulation, but the mechanism of this effect remains obscure. The…”
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Influence of calcium on the subcellular distribution of protein kinase C in human neutrophils. Extraction conditions determine partitioning of histone-phosphorylating activity and immunoreactivity between cytosol and particulate fractions by W A Phillips, T Fujiki, M W Rossi, H M Korchak, R B Johnston, Jr

“…Activation of the neutrophil respiratory burst is thought to involve a translocation and activation of protein kinase C. We report that the presence of Ca2+…”
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Mechanisms of host defense against Candida species. II. Biochemical basis for the killing of Candida by mononuclear phagocytes by Marodi, L, Forehand, JR, Johnston, RB, Jr

“…We studied the biochemical basis of candidacidal activity by comparing the killing of Candida albicans, a serious pathogen, and Candida parapsilosis, a…”
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Dissociation of phagocytosis from stimulation of the oxidative metabolic burst in macrophages by YAMAMOTO, K, JOHNSTON, R. B. JR

“…We explored the relationship between phagocytosis and the triggering of oxidative metabolism using resident, lipopolysaccharide (LPS)-elicited, and bacille…”
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Tissue injury in inflammation: oxidants, proteinases, and cationic proteins by HENSON, P. M, JOHNSTON, R. B. JR

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Priming of neutrophils and macrophages for enhanced release of superoxide anion by the calcium ionophore ionomycin. Implications for regulation of the respiratory burst by Finkel, T H, Pabst, M J, Suzuki, H, Guthrie, L A, Forehand, J R, Phillips, W A, Johnston, R B

“…Phagocytic cells can be primed for enhanced stimulated release of superoxide anion (O2-) by exposure to a variety of biologic agents, including…”
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