Search Results - "R A Rizza"

Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy by Butler, A. E, Cao-Minh, L, Galasso, R, Rizza, R. A, Corradin, A, Cobelli, C, Butler, P. C

“…Aims/hypothesis We sought to establish the extent and basis for adaptive changes in beta cell numbers in human pregnancy. Methods Pancreas was obtained at…”
Get full text

Pancreatic duct replication is increased with obesity and type 2 diabetes in humans by Butler, A. E., Galasso, R., Matveyenko, A., Rizza, R. A., Dry, S., Butler, P. C.

“…Aims/hypothesis In a high-fat-fed rat model of type 2 diabetes we noted increased exocrine duct replication. This is a predisposing factor for pancreatitis and…”
Get full text

Minimal model assessment of hepatic insulin extraction during an oral test from standard insulin kinetic parameters by Campioni, M, Toffolo, G, Basu, R, Rizza, R A, Cobelli, C

“…In this article, a first aim was to develop a minimal modeling approach to noninvasively assess hepatic insulin extraction in 204 healthy subjects studied with…”
Get more information

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? by Meier, J J, Bhushan, A, Butler, A E, Rizza, R A, Butler, P C

“…Type 1 diabetes is widely held to result from an irreversible loss of insulin-secreting beta cells. However, insulin secretion is detectable in some people…”
Get full text

Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis by Butler, A. E, Galasso, R, Meier, J. J, Basu, R, Rizza, R. A, Butler, P. C

“…Aims/hypothesis Type 1 diabetes is characterised by a deficit in beta cell mass thought to be due to immune-mediated increased beta cell apoptosis. Beta cell…”
Get full text

Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes by Saisho, Y., Butler, A.E., Meier, J.J., Monchamp, T., Allen-Auerbach, M., Rizza, R.A., Butler, P.C.

“…Our aims were (1) by computed tomography (CT) to establish a population database for pancreas volume (parenchyma and fat) from birth to age 100 years, (2) in…”
Get full text

Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans by MEIER, J. J, BUTLER, A. E, GALASSO, R, RIZZA, R. A, BUTLER, P. C

“…Type 1 and type 2 diabetes are characterised by a beta cell deficit. Islet hyperplasia has been described in patients with Zollinger-Ellison syndrome secondary…”
Get full text

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus by The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

“…Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus The Expert Committee on the Diagnosis and Classification of Diabetes…”
Get full text

Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans by VELLA, A, SHAH, P, REED, A. S, ADKINS, A. S, BASU, R, RIZZA, R. A

“…The aim of this study was to determine whether rapid conversion to inactive and potentially antagonistic peptides could alter the response to GLP-1. We…”
Get full text

A low frequency of pancreatic islet insulin-expressing cells derived from cord blood stem cell allografts in humans by Huang, C. J., Butler, A. E., Moran, A., Rao, P. N., Wagner, J. E., Blazar, B. R., Rizza, R. A., Manivel, J. C., Butler, P. C.

“…Aims/hypothesis We sought to establish if stem cells contained in cord blood cell allografts have the capacity to differentiate into insulin-expressing beta…”
Get full text

Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: evidence for a defect in hepatic glucokinase activity by BASU, A, BASU, R, SHAH, P, VELLA, A, JOHNSON, C. M, SREEKUMARAN NAIR, K, JENSEN, M. D, SCHWENK, W. F, RIZZA, R. A

“…Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: evidence for a defect in hepatic…”
Get full text

Extrapancreatic effects of GIP and GLP-1 by Vella, A, Rizza, R A

“…Incretin-based therapy promises to be a useful adjunct in the treatment of diabetes. Glucagon-like peptide-1 (GLP1) and, to a lesser extent, glucose-dependent…”
Get more information

Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans : effects of acute insulin withdrawal by MOLLER, N, JENSEN, M. D, RIZZA, R. A, ANDREWS, J. C, NAIR, K. S

“…The aim of this study was to test the hypothesis that type 1 diabetes alters renal amino acid, glucose and fatty acid metabolism. We studied five…”
Get full text

Effects of pioglitazone and metformin on NEFA-induced insulin resistance in type 2 diabetes by Basu, R, Basu, A, Chandramouli, V, Norby, B, Dicke, B, Shah, P, Cohen, O, Landau, B. R, Rizza, R. A

“…Aims/hypothesis We sought to determine whether pioglitazone and metformin alter NEFA-induced insulin resistance in type 2 diabetes and, if so, the mechanism…”
Get full text

Influence of body fat distribution on free fatty acid metabolism in obesity by JENSEN, M. D, HAYMOND, M. W, RIZZA, R. A, CRYER, P. E, MILES, J. M

“…In order to determine whether differences in body fat distribution result in specific abnormalities of free fatty acid (FFA) metabolism, palmitate turnover, a…”
Get full text

Effects of changing diagnostic criteria on the risk of developing diabetes by S F Dinneen, D Maldonado, 3rd, C L Leibson, G G Klee, H Li, L J Melton, 3rd, R A Rizza

“…Effects of changing diagnostic criteria on the risk of developing diabetes. S F Dinneen , D Maldonado, 3rd , C L Leibson , G G Klee , H Li , L J Melton, 3rd…”
Get full text

Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes by Vella, A, Shah, P, Basu, R, Basu, A, Holst, J J, Rizza, R A

“…Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes. A Vella , P Shah , R Basu , A Basu ,…”
Get full text

Glucose-induced suppression of endogenous glucose production: dynamic response to differing glucose profiles by Vella, A, Reed, A S, Charkoudian, N, Shah, P, Basu, R, Basu, A, Joyner, M J, Rizza, R A

“…To determine whether, in the presence of constant insulin concentrations, a change in glucose concentrations results in a reciprocal change in endogenous…”
Get more information

Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a concentration-dependent defect in uptake by NIELSEN, M. F, BASU, R, WISE, S, CAUMO, A, COBELLI, C, RIZZA, R. A

“…Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a…”
Get full text

Positive neuropathic sensory symptoms as endpoints in diabetic neuropathy trials by Apfel, S C, Asbury, A K, Bril, V, Burns, T M, Campbell, J N, Chalk, C H, Dyck, P J, Feldman, E L, Fields, H L, Grant, I A, Griffin, J W, Klein, C J, Lindblom, U, Litchy, W J, Low, P A, Melanson, M, Mendell, J R, Merren, M D, O'Brien, P C, Rendell, M, Rizza, R A, Service, F J, Thomas, P K, Walk, D, Wang, A K, Wessel, K, Windebank, A J, Ziegler, D, Zochodne, D W

Get full text