Search Results - "Rüger, Petra"

In vitro glycoengineering of IgG1 and its effect on Fc receptor binding and ADCC activity by Thomann, Marco, Schlothauer, Tilman, Dashivets, Tetyana, Malik, Sebastian, Avenal, Cecile, Bulau, Patrick, Rüger, Petra, Reusch, Dietmar

“…The importance and effect of Fc glycosylation of monoclonal antibodies with regard to biological activity is widely discussed and has been investigated in…”
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Delivery of the Brainshuttle™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans by Grimm, Hans Peter, Schumacher, Vanessa, Schäfer, Martin, Imhof-Jung, Sabine, Freskgård, Per-Ola, Brady, Kevin, Hofmann, Carsten, Rüger, Petra, Schlothauer, Tilman, Göpfert, Ulrich, Hartl, Maximilian, Rottach, Sylvia, Zwick, Adrian, Seger, Shanon, Neff, Rachel, Niewoehner, Jens, Janssen, Niels

“…There are few treatments that slow neurodegeneration in Alzheimer's disease (AD), and while therapeutic antibodies are being investigated in clinical trials…”
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A Pentacyclic Aurora Kinase Inhibitor (AKI-001) with High in Vivo Potency and Oral Bioavailability by Rawson, Thomas E, Rüth, Matthias, Blackwood, Elizabeth, Burdick, Dan, Corson, Laura, Dotson, Jenna, Drummond, Jason, Fields, Carter, Georges, Guy J, Goller, Bernhard, Halladay, Jason, Hunsaker, Thomas, Kleinheinz, Tracy, Krell, Hans-Willi, Li, Jun, Liang, Jun, Limberg, Anja, McNutt, Angela, Moffat, John, Phillips, Gail, Ran, Yingqing, Safina, Brian, Ultsch, Mark, Walker, Leslie, Wiesmann, Christian, Zhang, Birong, Zhou, Aihe, Zhu, Bing-Yan, Rüger, Petra, Cochran, Andrea G

“…Aurora kinase inhibitors have attracted a great deal of interest as a new class of antimitotic agents. We report a novel class of Aurora inhibitors based on a…”
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Development of a pre-glycoengineered CHO-K1 host cell line for the expression of antibodies with enhanced Fc mediated effector function by Popp, Oliver, Moser, Samuel, Zielonka, Jörg, Rüger, Petra, Hansen, Silke, Plöttner, Oliver

“…Novel biotherapeutic glycoproteins, like recombinant monoclonal antibodies (mAbs) are widely used for the treatment of numerous diseases. The N-glycans…”
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Mutants of Protein Kinase A that Mimic the ATP-binding Site of Protein Kinase B (AKT) by Gaßel, Michael, Breitenlechner, Christine B., Rüger, Petra, Jucknischke, Ute, Schneider, Thorsten, Huber, Robert, Bossemeyer, Dirk, Engh, Richard A.

“…The mutation of well behaved enzymes in order to simulate less manageable cognates is the obvious approach to study specific features of the recalcitrant…”
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Biosensor based on an enzyme modified electrode for highly-sensitive measurement of polyphenols by Eremenko, Arkadi, Makower, Alexander, Jin, Wen, Rüger, Petra, Scheller, Frieder

“…The use of glucose dehydrogenase from Acinetobacter calcoaceticus for highly sensitive measurement of polyphenols, based on bioelectrocatalytic analyte…”
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Delivery of the Brainshuttle™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans by Grimm, Hans Peter, Schumacher, Vanessa, Schäfer, Martin, Imhof-Jung, Sabine, Freskgård, Per-Ola, Brady, Kevin, Hofmann, Carsten, Rüger, Petra, Schlothauer, Tilman, Göpfert, Ulrich, Hartl, Maximilian, Rottach, Sylvia, Zwick, Adrian, Seger, Shanon, Neff, Rachel, Niewoehner, Jens, Janssen, Niels

“…There are few treatments that slow neurodegeneration in Alzheimer's disease (AD), and while therapeutic antibodies are being investigated in clinical trials…”
Get full text

Development of a pre-glycoengineered CHO-K1 host cell line for the expression of antibodies with enhanced Fc mediated effector function by Popp, Oliver, Moser, Samuel, Zielonka, Jörg, Rüger, Petra, Hansen, Silke, Plöttner, Oliver

“…Novel biotherapeutic glycoproteins, like recombinant monoclonal antibodies (mAbs) are widely used for the treatment of numerous diseases. The N-glycans…”
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Application of screen printed electrodes in biochemical analysis by Schmidt, Anja, Rohm, Ingrid, R ger, Petra, Weise, Wolfgang, Bilitewski, Ursula

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