Search Results - "Rückert, René"
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Differentiation of Underlying Pathologies of Macular Edema Using Spectral Domain Optical Coherence Tomography (SD-OCT)
Published in Ocular immunology and inflammation (03-04-2019)“…Purpose: To describe the morphological characteristics of macular edema (ME) of different origins using spectral domain optical coherence tomography (SD-OCT)…”
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A bioinformatic analysis: Previous allergen exposure may support anti- SARS-CoV-2 immune response
Published in Computational biology and chemistry (01-12-2023)“…COVID-19, caused by infection with the SARS-CoV-2 has become a global health problem due to significant mortality rates; the exact pathophysiological mechanism…”
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Using bioinformatic protein sequence similarity to investigate if SARS CoV-2 infection could cause an ocular autoimmune inflammatory reactions?
Published in Experimental eye research (01-02-2021)“…Although severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection have emerged globally, findings related to ocular involvement and reported…”
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How the immune response to the structural proteins of SARS-CoV-2 affects the retinal vascular endothelial cells: an immune thrombotic and/or endotheliopathy process with in silico modeling
Published in Immunologic research (01-02-2024)“…Thrombotic events associated with SARS-CoV-2 at the vascular endothelium still remains unclear. The aim of the current study is to determine the relationship…”
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Interleukin-21 inhibits dendritic cell activation and maturation
Published in Blood (01-12-2003)“…Interleukin 21 (IL-21) is a newly described cytokine with homology to IL-4 and IL-15. They belong to a cytokine family that uses the common γ chain for…”
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Expression of key SARS-CoV-2 entry molecules in surgically obtained human retinal biopsies
Published in International ophthalmology (01-12-2023)“…Purpose To investigate the presence of ACE2, TMPRSS2 and Furin, i.e., a key player in the ocular infection with SARS-COV-2, in surgically obtained human…”
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Blocking IL-15 Prevents the Induction of Allergen-Specific T Cells and Allergic Inflammation In Vivo
Published in The Journal of immunology (1950) (01-05-2005)“…IL-15 has been shown to accelerate and boost allergic sensitization in mice. Using a murine model of allergic sensitization to OVA, we present evidence that…”
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Inhibition of Keratinocyte Apoptosis by IL-15: A New Parameter in the Pathogenesis of Psoriasis?
Published in The Journal of immunology (1950) (15-08-2000)“…Keratinocytes (KC) are important source of and targets for several cytokines. Although KC express IL-15 mRNA, the functional effects of IL-15 on these…”
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MMP19 is essential for T cell development and T cell-mediated cutaneous immune responses
Published in PloS one (04-06-2008)“…Matrix metalloproteinase-19 (MMP19) affects cell proliferation, adhesion, and migration in vitro but its physiological role in vivo is poorly understood. To…”
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Interleukin-15 protects from lethal apoptosis in vivo
Published in Nature medicine (01-10-1997)“…Interleukin-15 shares many biological activities with IL-2 and signals through the IL-2 receptor beta and gamma chains. However, IL-15 and IL-2 differ in their…”
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A DOUBLE-MASKED, RANDOMIZED, SHAM-CONTROLLED, SINGLE-CENTER STUDY WITH PHOTOBIOMODULATION FOR THE TREATMENT OF DRY AGE-RELATED MACULAR DEGENERATION
Published in Retina (Philadelphia, Pa.) (01-08-2020)“…The LIGHTSITE I study investigated the efficacy and safety of photobiomodulation (PBM) treatment in subjects with dry age-related macular degeneration. Thirty…”
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The DA VINCI Study: Phase 2 Primary Results of VEGF Trap-Eye in Patients with Diabetic Macular Edema
Published in Ophthalmology (Rochester, Minn.) (01-09-2011)“…Purpose To determine whether different doses and dosing regimens of intravitreal vascular endothelial growth factor (VEGF) Trap-Eye are superior to focal/grid…”
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MHC Class I Expression in Murine Skin: Developmentally Controlled and Strikingly Restricted Intraepithelial Expression During Hair Follicle Morphogenesis and Cycling, and Response to Cytokine Treatment In Vivo
Published in Journal of investigative dermatology (01-07-1998)“…Hair bulb keratinocytes generate one of the few “immune privileged” tissue compartments of the mammalian organism by suppressing classical MHC class I (MHC Ia)…”
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The role of anti-VEGF agents in myopic choroidal neovascularization: Current standards and future outlook
Published in Expert opinion on biological therapy (02-04-2016)“…The global prevalence of pathologic myopia is 0.9-3.1%, and visual impairment is found in 0.1-0.5% of European and 0.2-1.4% of Asian studies. Myopic choroidal…”
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WORKING LIFE: To work or not shouldn't be a question
Published in Science (American Association for the Advancement of Science) (24-04-2015)Get full text
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To work or not shouldn't be a question
Published in Science (American Association for the Advancement of Science) (24-04-2015)Get full text
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Morphologic and functional evaluations during development, resolution, and relapse of uveitis-associated cystoid macular edema
Published in Retina (Philadelphia, Pa.) (01-09-2013)“…To describe progression and resolution of uveitis-associated cystoid macular edema (uvCME) using spectral-domain optical coherence tomography and find…”
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To work or not shouldn't be a question
Published in Science (American Association for the Advancement of Science) (24-04-2015)Get full text
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One-Year Outcomes of the DA VINCI Study of VEGF Trap-Eye in Eyes with Diabetic Macular Edema
Published in Ophthalmology (Rochester, Minn.) (01-08-2012)“…Purpose To compare different doses and dosing regimens of Vascular Endothelial Growth Factor (VEGF) Trap-Eye with laser photocoagulation in eyes with diabetic…”
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