Search Results - "Röpke, A."

Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest by van der Bijl, N, Röpke, A, Biswas, U, Wöste, M, Jessberger, R, Kliesch, S, Friedrich, C, Tüttelmann, F

“…Abstract STUDY QUESTION Are sequence variants in the stromal antigen 3 (STAG3) gene a cause for non-obstructive azoospermia (NOA) in infertile human males?…”
Get full text

A novel xeno-organoid approach: exploring the crosstalk between human iPSC-derived PGC-like and rat testicular cells by Mall, E M, Rotte, N, Yoon, J, Sandhowe-Klaverkamp, R, Röpke, A, Wistuba, J, Hübner, K, Schöler, H R, Schlatt, S

“…Abstract Specification of germ cell-like cells from induced pluripotent stem cells has become a clinically relevant tool for research. Research on initial…”
Get full text

Copy number variants in premature ovarian failure and ovarian dysgenesis by Ledig, S, Röpke, A, Wieacker, P

“…Premature ovarian failure (POF) is a heterogeneous group of disorders with amenorrhea and high serum gonadotropins in women of less than 40 years. Ovarian…”
Get more information

Analysis of copy number variation in men with non‐obstructive azoospermia by Wyrwoll, M. J., Wabschke, R., Röpke, A., Wöste, M., Ruckert, C., Perrey, S., Rotte, N., Hardy, J., Astica, L., Lupiáñez, D. G., Wistuba, J., Westernströer, B., Schlatt, S., Berman, A. J., Müller, A. M., Kliesch, S., Yatsenko, A. N., Tüttelmann, F., Friedrich, C.

“…Background Recent findings demonstrate that single nucleotide variants can cause non‐obstructive azoospermia (NOA). In contrast, copy number variants (CNVs)…”
Get full text

Blood chimerism in a girl with Down syndrome and possible freemartin effect leading to aplasia of the Müllerian derivatives by Bogdanova, N., Siebers, U., Kelsch, R., Markoff, A., Röpke, A., Exeler, R., Tsokas, J., Wieacker, P.

“…Cytogenetic and molecular genetic analysis in a case of sex-discordant dizygotic twins revealed blood chimerism in the girl (46,XY in blood and 47,XX, + 21 in…”
Get full text

Calcipotriol and betamethasone dipropionate exert additive inhibitory effects on the cytokine expression of inflammatory dendritic cell–Th17 cell axis in psoriasis by Lovato, Paola, Norsgaard, Hanne, Tokura, Yoshiki, Røpke, Mads A

“…Highlights • Calcipotriol significantly adds to the anti-inflammatory activity of betamethasone. • Calcipotriol has a unique immune modulatory effect on…”
Get full text

Tralokinumab does not impact vaccine-induced immune responses: Results from a 30-week, randomized, placebo-controlled trial in adults with moderate-to-severe atopic dermatitis by Merola, Joseph F., Bagel, Jerry, Almgren, Peter, Røpke, Mads A., Lophaven, Katja W., Vest, Natacha Strange, Grewal, Parbeer

“…Atopic dermatitis (AD) is a chronic inflammatory skin disease. Interleukin (IL) 13 is a type 2 cytokine that is key to the inflammation underlying AD…”
Get full text

Interleukin-13 inhibition by tralokinumab reduces inducible T-cell costimulator-positive innate lymphoid cells in skin lesions of atopic dermatitis by Kogame, Toshiaki, Yonekura, Satoru, Lovato, Paola, Hirata, Masahiro, Takimoto-Ito, Riko, Takegami, Tomoya, Komatsu-Fujii, Takayoshi, Kambe, Naotomo, Nomura, Takashi, Røpke, Mads A, Kabashima, Kenji

“…Despite the low frequency of skin ILCs and the limited number of samples analyzed in this study, our data indicate that ICOS+ ILCs express IL-13Rα1 and that…”
Get full text

MicroRNA-223 and miR-143 are important systemic biomarkers for disease activity in psoriasis by Løvendorf, Marianne B, Zibert, John R, Gyldenløve, Mette, Røpke, Mads A, Skov, Lone

“…Highlights • MicroRNAs are detectable in whole blood, plasma and PBMCs from patients with psoriasis. • We identified significant changes in the miRNome of…”
Get full text

PLAG1 activation in lipoblastoma coinciding with low-level amplification of a derivative chromosome 8 with a deletion del(8)(q13q21.2) by Röpke, A, Kalinski, T, Kluba, U, von Falkenhausen, U, Wieacker, P F, Röpke, M

“…Lipoblastoma is a benign uncommon soft-tissue-tumor resembling fetal adipose tissue affecting mainly children under three years of age. In lipoblastoma, the…”
Get more information

Effects of topical corticosteroid versus tacrolimus on insulin sensitivity and bone homeostasis in adults with atopic dermatitis—A randomized controlled study by Gether, Lise, Storgaard, Heidi, Kezic, Sanja, Jakasa, Ivone, Hartmann, Bolette, Skov‐Jeppesen, Kirsa, Holst, Jens J., Pedersen, Anders J., Forman, Julie, Hall, Gerrit, Sørensen, Ole E., Skov, Lone, Røpke, Mads A., Knop, Filip K., Thyssen, Jacob Pontoppidan

“…Introduction Topical corticosteroids (TCS), used to treat atopic dermatitis (AD), have been associated with type 2 diabetes and osteoporosis in epidemiological…”
Get full text

Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL) by Ralfkiaer, Ulrik, Hagedorn, Peter H., Bangsgaard, Nannie, Løvendorf, Marianne B., Ahler, Charlotte B., Svensson, Lars, Kopp, Katharina L., Vennegaard, Marie T., Lauenborg, Britt, Zibert, John R., Krejsgaard, Thorbjørn, Bonefeld, Charlotte M., Søkilde, Rolf, Gjerdrum, Lise M., Labuda, Tord, Mathiesen, Anne-Merete, Grønbæk, Kirsten, Wasik, Mariusz A., Sokolowska-Wojdylo, Malgorzata, Queille-Roussel, Catherine, Gniadecki, Robert, Ralfkiaer, Elisabeth, Geisler, Carsten, Litman, Thomas, Woetmann, Anders, Glue, Christian, Røpke, Mads A., Skov, Lone, Odum, Niels

“…Cutaneous T-cell lymphomas (CTCLs) are the most frequent primary skin lymphomas. Nevertheless, diagnosis of early disease has proven difficult because of a…”
Get full text

EASI p-EASI: Predicting Disease Severity in Patients with Atopic Dermatitis Treated with Tralokinumab by Olydam, Jill I., de Wijs, Linde E.M., Dik, Willem A., Røpke, Mads A., Da Rosa, Joel Correa, Hijnen, Dirk Jan

Get full text

Multispectral imaging of hand eczema by Hald, Marianne, Thyssen, Jacob P., Zachariae, Claus, Røpke, Mads A., Carstensen, Jens M., Schultz, Nette, Johansen, Jeanne D.

“…Background Hand eczema is a disease with large variation in clinical presentation and severity. Scoring systems for quantitative severity assessment exist…”
Get full text

Skin and systemic inflammation in adults with atopic dermatitis before and after whole-body topical betamethasone 17-valerate 0.1% or tacrolimus 0.1% treatment: A randomized controlled study by Gether, Lise, Linares, Helena P I, Kezic, Sanja, Jakasa, Ivone, Forman, Julie, Sørensen, Ole E, Storgaard, Heidi, Skov, Lone, Røpke, Mads A, Knop, Filip K, Thyssen, Jacob P

“…Atopic dermatitis (AD) is mainly driven by type 2 inflammation and often treated with topical agents. Studies comparing differences in biomarkers between these…”
Get full text

Effects of glucocorticoids on stratum corneum lipids and function in human skin—A detailed lipidomic analysis by Røpke, Mads A., Alonso, Cristina, Jung, Sora, Norsgaard, Hanne, Richter, Claudia, Darvin, Maxim E., Litman, Thomas, Vogt, Annika, Lademann, Jürgen, Blume-Peytavi, Ulrike, Kottner, Jan

“…•Topical corticosteroid treatment induces significant changes in the stratum corneum lipid profile of human skin.•Clobetasol propionate induces more profound…”
Get full text

Laser capture microdissection followed by next-generation sequencing identifies disease-related microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis by Løvendorf, Marianne B., Mitsui, Hiroshi, Zibert, John R., Røpke, Mads A., Hafner, Markus, Dyring-Andersen, Beatrice, Bonefeld, Charlotte M., Krueger, James G., Skov, Lone

“…Psoriasis is a systemic disease with cutaneous manifestations. MicroRNAs (miRNAs) are small non‐coding RNA molecules that are differentially expressed in…”
Get full text

Anti‐inflammatory potency testing of topical corticosteroids and calcineurin inhibitors in human volunteers sensitized to diphenylcyclopropenone by Mose, Kristian F., Andersen, Flemming, Røpke, Mads A., Skov, Lone, Friedmann, Peter S., Andersen, Klaus E.

“…Aims To quantify the anti‐inflammatory potency of topical corticosteroids and topical calcineurin inhibitors by measuring the contact allergic response to a…”
Get full text

Repeated monthly epicutaneous challenges with diphenylcyclopropenone result in a clinically reproducible level of contact allergy in de novo sensitized individuals by Mose, K.F., Andersen, F., Skov, L., Røpke, M.A., Litman, T., Friedmann, P.S., Andersen, K.E.

Get full text

Corrigendum to “Calcipotriol and betamethasone dipropionate exert additive inhibitory effects on the cytokine expression of inflammatory dendritic cell-Th17 cell axis in psoriasis” [J. Dermatol. Sci. 81 (2016) 153–164] by Lovato, Paola, Norsgaard, Hanne, Tokura, Yoshiki, Røpke, Mads A

Get full text