Search Results - "Röder, Laurence"

Epi-MEIF: detecting higher order epistatic interactions for complex traits using mixed effect conditional inference forests by Saha, Saswati, Perrin, Laurent, Röder, Laurence, Brun, Christine, Spinelli, Lionel

“…Understanding the relationship between genetic variations and variations in complex and quantitative phenotypes remains an ongoing challenge. While Genome-wide…”
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Cardiac pathologies and aging: lessons from a tiny heart by Perrin, Laurent, Röder, Laurence

“…The high level of conservation of the cardiogenic gene regulatory network as well as of the cellular and physiological characteristics of the cardiomyocytes…”
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Genes and networks regulating cardiac development and function in flies: genetic and functional genomic approaches by Seyres, Denis, Röder, Laurence, Perrin, Laurent

“…The Drosophila heart has emerged as a powerful model system for cardiovascular research. This simple organ, composed of only 104 cardiomyocytes and associated…”
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Genetic architecture of natural variation of cardiac performance from flies to humans by Saha, Saswati, Spinelli, Lionel, Castro Mondragon, Jaime A, Kervadec, Anaïs, Lynott, Michaela, Kremmer, Laurent, Roder, Laurence, Krifa, Sallouha, Torres, Magali, Brun, Christine, Vogler, Georg, Bodmer, Rolf, Colas, Alexandre R, Ocorr, Karen, Perrin, Laurent

“…Deciphering the genetic architecture of human cardiac disorders is of fundamental importance but their underlying complexity is a major hurdle. We investigated…”
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Interplay between trauma and Pseudomonas entomophila infection in flies: a central role of the JNK pathway and of CrebA by Ragheb, Ramy, Chuyen, Alexandre, Torres, Magali, Defaye, Arnaud, Seyres, Denis, Kremmer, Laurent, Fernandez-Nunez, Nicolas, Tricoire, Hervé, Rihet, Pascal, Nguyen, Catherine, Röder, Laurence, Perrin, Laurent

“…In mammals, both sterile wounding and infection induce inflammation and activate the innate immune system, and the combination of both challenges may lead to…”
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Expression of cardiac myosin-binding protein-C (cMyBP-C) in Drosophila as a model for the study of human cardiomyopathies by Manh, Thien Phong Vu, Mokrane, Mustapha, Georgenthum, Emmanuelle, Flavigny, Jeanne, Carrier, Lucie, Sémériva, Michel, Piovant, Michel, Röder, Laurence

“…Mutations in the MYBPC3 gene encoding human cardiac myosin-binding protein-C (cMyBP-C) are associated with familial hypertrophic cardiomyopathy (FHC), but the…”
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Identification and in silico modeling of enhancers reveals new features of the cardiac differentiation network by Seyres, Denis, Ghavi-Helm, Yad, Junion, Guillaume, Taghli-Lamallem, Ouarda, Guichard, Céline, Röder, Laurence, Girardot, Charles, Furlong, Eileen E M, Perrin, Laurent

“…Developmental patterning and tissue formation are regulated through complex gene regulatory networks (GRNs) driven through the action of transcription factors…”
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The role of the teashirt gene in trunk segmental identity in Drosophila by RÖDER, L, VOLA, C, KERRIDGE, S

“…The phenotypes of different mutant combinations of teashirt (tsh) and homeotic genes together with their regulatory interactions are described in order to gain…”
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Grasping at molecular interactions and genetic networks in Drosophila melanogaster using FlyNets, an Internet database by Sanchez, Catherine, Lachaize, Corinne, Janody, Florence, Bellon, Bernard, Röder, Laurence, Euzenat, Jérôme, Rechenmann, François, Jacq, Bernard

“…Flynets (http://gifts.univ-mrs.fr/FlyNets/FlyNets_home_page.html) is a WWW database describing molecular interactions (protein-DNA, protein-RNA and…”
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Approaches combining mice and Drosophila melanogaster models to decipher human sepsis by Ramy, R, Garnier, S, Pradel, L, Röder, L, Loriod, B, Defaye, A, Perrin, L, Rihet, P, Nguyen, C

“…Keywords: Oleic Acid, Peripheral Blood Mononuclear Cell, Reference Panel, Sterile Inflammation, Complex Biological Process…”
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The genetic architecture of natural variations of cardiac aging in fly: New insights in cardiac senescence by Audouin, Katell, Saha, Saswati, Roder, Laurence, Perrin, Laurent

“…Risks of cardiovascular diseases increases drastically in aging populations, but the genetic basis for interindividual variation in cardiac senescence remains…”
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Genetic architecture of cardiac aging: A fly perspective by Audouin, Katell, Saha, Saswati, Roder, Laurence, Perrin, Laurent

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Genetic architecture of natural variation of cardiac performance from flies to humans by Saha, Saswati, Spinelli, Lionel, Castro Mondragon, Jaime, Kervadec, Anaïs, Lynott, Michaela, Kremmer, Laurent, Roder, Laurence, Krifa, Sallouha, Torres, Magali, Brun, Christine, Vogler, Georg, Bodmer, Rolf, Colas, Alexandre, Ocorr, Karen, Perrin, Laurent

“…Deciphering the genetic architecture of human cardiac disorders is of fundamental importance but their underlying complexity is a major hurdle. We investigated…”
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The gene teashirt is required for the development of Drosophila embryonic trunk segments and encodes a protein with widely spaced zinc finger motifs by Fasano, L, Röder, L, Coré, N, Alexandre, E, Vola, C, Jacq, B, Kerridge, S

“…We have discovered a reporter gene insertion that is expressed in the trunk region of Drosophila embryos. Genetic and molecular details of a new regulatory…”
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Grasping at molecular interactions and genetic networks in Drosophila melanogaster using FlyNets, an Internet database by Lachaize, C., Janody, F., Bellon, B., Röder, Laurence, Euzenat, J., Rechenmann, F., Jacq, B., Sanchez, Catherine

“…FlyNets (gifts.univ‐mrs.fr/FlyNets/FlyNets\ₕome\ₚage.++ +html) is a WWW database describing molecular interactions (protein‐DNA, protein‐RNA and…”
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FlyNets and GIF-DB, two Internet databases for molecular interactions in Drosophila melanogaster by Mohr, Elodie, Horn, Florence, Janody, Florence, Sanchez, Catherine, Pillet, Violaine, Bellon, Bernard, Röder, Laurence, Jacq, Bernard

“…GIF-DB and FlyNets are two WWW databases describing molecular (protein-DNA, protein-RNA and protein-protein) interactions occuring in the fly Drosophila…”
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GIF-DB, a WWW database on gene interactions involved in Drosophila melanogaster development by Jacq, B, Horn, F, Janody, F, Gompel, N, Serralbo, O, Mohr, E, Leroy, C, Bellon, B, Fasano, L, Laurenti, P

“…GIF-DB (Gene Interactions in the Fly Database) is a new WWW database (...) describing gene molecular interactions involved in the process of embryonic pattern…”
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A Drosophila rotund Transcript Expressed during Spermatogenesis and Imaginal Disc Morphogenesis Encodes a Protein Which Is Similar to Human Rac GTPase-Activating (racGAP) Proteins by Agnel, Magali, Röder, Laurence, Vola, Christine, Griffin-Shea, Ruth

“…The rotund (rn) locus of Drosophila melanogaster at cytogenetic position 84D3,4 has been isolated and cloned on the basis of the mutant phenotype: an absence…”
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The spatial expression ofDrosophila rotund gene reveals that the imaginal discs are organized in domains along the proximal-distal axis by Agnel, Magali, R der, Laurence, Griffin-Shea, Ruth, Vola, Christine

“…InDrosophila imaginal discs, pattern formation requires the activity of three positional information systems, antero‐posterior (A/P), dorso‐ventral (D/V) and…”
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