Search Results - "Ríos, Rosa M."
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TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin
Published in eLife (25-01-2021)“…TRIM37 is an E3 ubiquitin ligase mutated in Mulibrey nanism, a disease with impaired organ growth and increased tumor formation. TRIM37 depletion from tissue…”
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Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c
Published in Redox biology (01-07-2021)“…Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by Protein Phosphatase 2A (PP2A)…”
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3
CRISPR-Cas system presents multiple transcriptional units including antisense RNAs that are expressed in minimal medium and upregulated by pH in Salmonella enterica serovar Typhi
Published in Microbiology (Society for General Microbiology) (01-02-2017)“…The CRISPR-Cas system is involved in bacterial immunity, virulence, gene regulation, biofilm formation and sporulation. In Salmonella enterica serovar Typhi,…”
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Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus
Published in Journal of neuroinflammation (04-05-2012)“…Neuroinflammation and protein accumulation are characteristic hallmarks of both normal aging and age-related neurodegenerative diseases. However, the…”
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PTTG1/securin modulates microtubule nucleation and cell migration
Published in Molecular biology of the cell (15-11-2011)“…Pituitary tumor transforming gene 1 (PTTG1), also known as securin, has been implicated in many biological functions, including inhibition of sister chromatid…”
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PhyloFlu, a DNA Microarray for Determining the Phylogenetic Origin of Influenza A Virus Gene Segments and the Genomic Fingerprint of Viral Strains
Published in Journal of Clinical Microbiology (01-03-2014)“…Classifications Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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7
The centrosome–Golgi apparatus nexus
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-09-2014)“…A shared feature among all microtubule (MT)-dependent processes is the requirement for MTs to be organized in arrays of defined geometry. At a fundamental…”
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Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130
Published in The EMBO journal (22-04-2009)“…We report that microtubule (MT) nucleation at the Golgi apparatus requires AKAP450, a centrosomal γ‐TuRC‐interacting protein that also forms a distinct network…”
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The dual role of the centrosome in organizing the microtubule network in interphase
Published in EMBO reports (01-11-2018)“…Here, we address the regulation of microtubule nucleation during interphase by genetically ablating one, or two, of three major mammalian γ‐TuRC‐binding…”
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10
Noninvasive brain stimulation in psychiatric disorders: a primer
Published in Revista brasileira de psiquiatria (01-01-2019)“…Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation…”
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11
Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis
Published in The Journal of cell biology (30-05-2011)“…Mammalian cells exhibit a frequent pericentrosomal Golgi ribbon organization. In this paper, we show that two AKAP450 N-terminal fragments, both containing the…”
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Numb/Numbl-Opo Antagonism Controls Retinal Epithelium Morphogenesis by Regulating Integrin Endocytosis
Published in Developmental cell (16-10-2012)“…Polarized trafficking of adhesion receptors plays a pivotal role in controlling cellular behavior during morphogenesis. Particularly, clathrin-dependent…”
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Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid–liquid phase separation
Published in Nature structural & molecular biology (01-10-2022)“…The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered unrelated processes, yet cytochrome c (C c ) migrates to the nucleus…”
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GMAP-210 Recruits γ-Tubulin Complexes to cis-Golgi Membranes and Is Required for Golgi Ribbon Formation
Published in Cell (06-08-2004)“…Mammalian cells concentrate Golgi membranes around the centrosome in a microtubule-dependent manner. The mechanisms involved in generating a single Golgi…”
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Microfluidic-assisted preparation of RGD-decorated nanoparticles: exploring integrin-facilitated uptake in cancer cell lines
Published in Scientific reports (02-09-2020)“…This study is about fine tuning the targeting capacity of peptide-decorated nanoparticles to discriminate between cells that express different integrin…”
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Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
Published in Nature communications (28-06-2019)“…The T cell immune synapse is a site of intense vesicular trafficking. Here we show that the golgin GMAP210, known to capture vesicles and organize membrane…”
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Alpha-catenin-dependent recruitment of the centrosomal protein CAP350 to adherens junctions allows epithelial cells to acquire a columnar shape
Published in PLoS biology (01-03-2015)“…Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton. How this complex process is controlled at the molecular level is…”
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GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome–acroplaxome complex, head–tail coupling apparatus and tail
Published in Developmental dynamics (01-03-2011)“…We describe the localization of the golgin GMAP210 and the intraflagellar protein IFT88 in the Golgi of spermatids and the participation of these two proteins…”
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Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
Published in Aging cell (01-12-2009)“…Summary Dysfunctions of the ubiquitin proteasome system (UPS) have been proposed to be involved in the aetiology and/or progression of several age‐related…”
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The CD44‐Mediated Uptake of Hyaluronic Acid‐Based Carriers in Macrophages
Published in Advanced healthcare materials (01-02-2017)“…CD44 is a potentially rewarding target in cancer therapy, although its mechanisms of ligand binding and internalization are still poorly understood. In this…”
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