Search Results - "Río, Marcela del"

The importance of immunity in the development of reliable animal models for psoriasis and atopic dermatitis by Guerrero‐Aspizua, Sara, Carretero, Marta, Conti, Claudio J, Del Río, Marcela

“…Psoriasis (PS) and atopic dermatitis (AD) are common inflammatory skin diseases characterized by an imbalance in specific T‐cell subsets, resulting in a…”
Get full text

In vitro and In vivo Wound Healing-Promoting Activities of Human Cathelicidin LL-37 by Carretero, Marta, Escámez, María J., García, Marta, Duarte, Blanca, Holguín, Almudena, Retamosa, Luisa, Jorcano, Jose L., Río, Marcela del, Larcher, Fernando

“…The human antimicrobial peptide LL-37 plays an important role in host defense against infection. In addition to its antimicrobial action, other activities have…”
Get full text

Unveiling the value of C‐reactive protein as a severity biomarker and the IL4/IL13 pathway as a therapeutic target in recessive dystrophic epidermolysis bullosa: A multiparametric cross‐sectional study by Quintana‐Castanedo, Lucía, Sánchez‐Ramón, Silvia, Maseda, Rocío, Illera, Nuria, Pérez‐Conde, Isabel, Molero‐Luis, Marta, Butta, Nora, Arias‐Salgado, Elena G., Monzón‐Manzano, Elena, Zuluaga, Pilar, Martínez‐Santamaría, Lucía, Fernández‐Arquero, Miguel, Llames, Sara G., Meana, Álvaro, Lucas, Raúl, Río, Marcela, Vicente, Ángeles, Escámez, María José, Sacedón, Rosa

“…Patients with recessive dystrophic epidermolysis bullosa (RDEB) experience numerous complications, which are exacerbated by inflammatory dysregulation and…”
Get full text

Long-Term Skin Regeneration From a Gene-Targeted Human Epidermal Stem Cell Clone by Duarte, Blanca, Miselli, Francesca, Murillas, Rodolfo, Espinosa-Hevia, Luis, Cigudosa, Juan Cruz, Recchia, Alessandra, Del Río, Marcela, Larcher, Fernando

Get full text

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer by Puig-Butille, Joan Anton, Escámez, María José, Garcia-Garcia, Francisco, Tell-Marti, Gemma, Fabra, Àngels, Martínez-Santamaría, Lucía, Badenas, Celia, Aguilera, Paula, Pevida, Marta, Dopazo, Joaquín, del Río, Marcela, Puig, Susana

“…Germline mutations in CDKN2A and/or red hair color variants in MC1R genes are associated with an increased susceptibility to develop cutaneous melanoma or non…”
Get full text

Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis by Puig-Butille, Joan Anton, Gimenez-Xavier, Pol, Visconti, Alessia, Nsengimana, Jérémie, Garcia-García, Francisco, Tell-Marti, Gemma, Escamez, Maria José, Newton-Bishop, Julia, Bataille, Veronique, Del Río, Marcela, Dopazo, Joaquín, Falchi, Mario, Puig, Susana

“…The MC1R gene plays a crucial role in pigmentation synthesis. Loss-of-function MC1R variants, which impair protein function, are associated with red hair color…”
Get full text

IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development by Alameda, Josefa P, Navarro, Manuel, Ramírez, Ángel, Page, Angustias, Suárez-Cabrera, Cristian, Moreno-Maldonado, Rodolfo, Paramio, Jesús M, del Carmen Fariña, María, Del Río, Marcela, Fernández-Aceñero, María Jesús, Bravo, Ana, de Los Llanos Casanova, María

“…IKKα plays a mandatory role in keratinocyte differentiation and exerts an important task in non-melanoma skin cancer development. However, it is not fully…”
Get full text

Trends of maxillofacial trauma: An update from the prospective register of a multicenter study in emergency services of Chile by Werlinger, F, Villalón, M, Duarte, V, Acevedo, R, Aguilera, R, Alcocer, D, Badillo, O, Briones, R, Condal, C, Del Río, M, García, R, Herrera, M, Jaramillo, J, Merchan, F, Nasi, M, Osbén, R, Rivera, A, Riviello, S, Rojas, P, Vidal, C, Rodríguez, G, Schild, S, Arroyo, E, Alvarado, M-J, Sepúlveda, P, Cortés, J

“…Determine the behavior of the maxillofacial trauma of adults treated in 3 tertiary care centers in the central zone of Chile. descriptive, cross-sectional,…”
Get full text

An In Vivo Model of Wound Healing in Genetically Modified Skin-Humanized Mice by Escámez, María José, García, Marta, Larcher, Fernando, Meana, Alvaro, Muñoz, Evangelina, Jorcano, Jose Luis, Del Río, Marcela

“…Cutaneous wound-healing disorders are a major health problem that requires the development of innovative treatments. Whithin this context, the search for…”
Get full text

The effect of benzo[a]pyrene on the gut microbiota of Nile tilapia (Oreochromis niloticus) by Quintanilla-Mena, Mercedes, Vega-Arreguin, Julio, Del Río-García, Marcela, Patiño-Suárez, Victoria, Peraza-Echeverria, Santy, Puch-Hau, Carlos

“…Benzo[a]pyrene (BaP) is a highly toxic and carcinogenic polycyclic aromatic hydrocarbon (PAH) whose toxicological effects in the gut microbiota of aquatic…”
Get full text

Toxicity evaluation and microbiota response of the lined sole Achirus lineatus (Chordata: Achiridae) exposed to the light petroleum water-accommodated fraction (WAF) by Améndola-Pimenta, Mónica, Cerqueda-García, Daniel, Zamora-Briseño, Jesús A., Couoh-Puga, Danilú, Montero-Muñoz, Jorge, Árcega-Cabrera, Flor, Ceja-Moreno, Víctor, Pérez-Vega, Juan A., García-Maldonado, José Q., del Río-García, Marcela, Zapata-Pérez, Omar, Rodríguez-Canul, Rossanna

“…Exposure to contaminants might directly affect organisms and alter their associated microbiota. The objective of the present study was to determine the impact…”
Get full text

Partial mRNA Sequences of the Biomarkers CYP1A, GST, CAT, GR, SOD, GPx, VTG and p53 in Flatfish Syacium gunteri from Gulf of Mexico by Puch-Hau, Carlos, Quintanilla-Mena, Mercedes, Rubio-Piña, Jorge, Del Río-García, Marcela, Zapata-Pérez, Omar

“…The present study reports partial sequences of a group of genes used as exposure and effect biomarkers of organic contaminants and/or heavy metals in Syacium…”
Get full text

Clinically Relevant Correction of Recessive Dystrophic Epidermolysis Bullosa by Dual sgRNA CRISPR/Cas9-Mediated Gene Editing by Bonafont, Jose, Mencía, Ángeles, García, Marta, Torres, Raúl, Rodríguez, Sandra, Carretero, Marta, Chacón-Solano, Esteban, Modamio-Høybjør, Silvia, Marinas, Lucía, León, Carlos, Escamez, María J., Hausser, Ingrid, Del Río, Marcela, Murillas, Rodolfo, Larcher, Fernando

“…Gene editing constitutes a novel approach for precisely correcting disease-causing gene mutations. Frameshift mutations in COL7A1 causing recessive dystrophic…”
Get full text

Gill and liver transcriptomic responses of Achirus lineatus (Neopterygii: Achiridae) exposed to water-accommodated fraction (WAF) of light crude oil reveal an onset of hypoxia-like condition by Zamora-Briseño, Jesús Alejandro, Améndola-Pimenta, Monica, Ortega-Rosas, Daniel Antonio, Pereira-Santana, Alejandro, Hernández-Velázquez, Ioreni Margarita, González-Penagos, Carlos Eduardo, Pérez-Vega, Juan Antonio, del Río-García, Marcela, Árcega-Cabrera, Flor, Rodríguez-Canul, Rossanna

“…Crude oil is one of the most widespread pollutants released into the marine environment, and native species have provided useful information about the effect…”
Get full text

Effects of photodynamic therapy on dermal fibroblasts from xeroderma pigmentosum and Gorlin-Goltz syndrome patients by Zamarrón, Alicia, García, Marta, Río, Marcela Del, Larcher, Fernando, Juarranz, Ángeles

“…PDT is widely applied for the treatment of non-melanoma skin cancer pre-malignant and malignant lesions (actinic keratosis, basal cell carcinoma and squamous…”
Get full text

Topical Enzyme-Replacement Therapy Restores Transglutaminase 1 Activity and Corrects Architecture of Transglutaminase-1-Deficient Skin Grafts by Aufenvenne, Karin, Larcher, Fernando, Hausser, Ingrid, Duarte, Blanca, Oji, Vinzenz, Nikolenko, Heike, Del Rio, Marcela, Dathe, Margitta, Traupe, Heiko

“…Transglutaminase-1 (TG1)-deficient autosomal-recessive congenital ichthyosis (ARCI) is a rare and severe genetic skin disease caused by mutations in TGM1. It…”
Get full text

Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells by Mencía, Ángeles, Chamorro, Cristina, Bonafont, Jose, Duarte, Blanca, Holguin, Almudena, Illera, Nuria, Llames, Sara G., Escámez, Maria José, Hausser, Ingrid, Del Río, Marcela, Larcher, Fernando, Murillas, Rodolfo

“…Recessive dystrophic epidermolysis bullosa is a severe skin fragility disease caused by loss of functional type VII collagen at the dermal-epidermal junction…”
Get full text

Humanization of Tumor Stroma by Tissue Engineering as a Tool to Improve Squamous Cell Carcinoma Xenograft by Guerrero-Aspizua, Sara, González-Masa, Andrea, Conti, Claudio J, García, Marta, Chacón-Solano, Esteban, Larcher, Fernando, Del Río, Marcela

“…The role of stroma is fundamental in the development and behavior of epithelial tumors. In this regard, limited growth of squamous cell carcinomas (SCC) or…”
Get full text

Combined adipose mesenchymal stromal cell advanced therapy resolved a recalcitrant leg ulcer in an 85-year-old patient by Martínez-Santamaría, Lucía, Cárcamo, Carmen, García-Pardo, Lourdes, García-Arranz, Mariano, Melen, Gustavo, Guerrero-Aspizua, Sara, Llanos, Lucía, Río, Marcela Del, García-Olmo, Damián, Escámez, María-José

“…Venous leg ulcers (VLU) represent an uphill economic, health and social burden, aggravated in the elderly. Best-practice care interventions are often…”
Get full text

Transcriptomic Analysis of a Diabetic Skin-Humanized Mouse Model Dissects Molecular Pathways Underlying the Delayed Wound Healing Response by León, Carlos, García-García, Francisco, Llames, Sara, García-Pérez, Eva, Carretero, Marta, Arriba, María Del Carmen, Dopazo, Joaquín, Del Río, Marcela, Escámez, María José, Martínez-Santamaría, Lucía

“…Defective healing leading to cutaneous ulcer formation is one of the most feared complications of diabetes due to its consequences on patients' quality of life…”
Get full text