Search Results - "Rêgo, Eduardo"

A methodology for fretting fatigue life estimation using strain-based fracture mechanics by Fontes do Rêgo, Eduardo Martins, Antunes, Marcelo Avelar, de Oliveira Miranda, Antonio Carlos

“…•Provides a Strain-based Fracture Mechanics methodology to compute fretting fatigue life.•Provides a model capable of predicting short and long crack behavior,…”
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Stress intensity factor solutions for fretting fatigue using stress gradient factor by Antunes, Marcelo Avelar, da Silva, Cosme Roberto Moreira, do Rêgo, Eduardo Martins Fontes, de Oliveira Miranda, Antonio Carlos

“…•Provides Stress Intensity Factor solutions for Fretting Fatigue.•Presents the Stress Gradient Factor applied to Fretting Fatigue.•Presents a set of results…”
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The challenge of timely diagnosis and management of acute leukemias and associated infections in Latin America by Rego, Eduardo Magalhães

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Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet by Sanz, Miguel A., Fenaux, Pierre, Tallman, Martin S., Estey, Elihu H., Löwenberg, Bob, Naoe, Tomoki, Lengfelder, Eva, Döhner, Hartmut, Burnett, Alan K., Chen, Sai-Juan, Mathews, Vikram, Iland, Harry, Rego, Eduardo, Kantarjian, Hagop, Adès, Lionel, Avvisati, Giuseppe, Montesinos, Pau, Platzbecker, Uwe, Ravandi, Farhad, Russell, Nigel H., Lo-Coco, Francesco

“…Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 2009, several studies have provided important…”
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Therapeutic plasma exchange and HLA desensitization by Rego, Eduardo Magalhães

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(–)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1 by Della Via, Fernanda Isabel, Shiraishi, Rodrigo Naoto, Santos, Irene, Ferro, Karla Priscila, Salazar-Terreros, Myriam Janeth, Franchi Junior, Gilberto Carlos, Rego, Eduardo Magalhães, Saad, Sara Teresinha Olalla, Torello, Cristiane Okuda

“…(–)-Epigallocatechin-3-gallate (EGCG), the major active polyphenol extracted from green tea, has been shown to induce apoptosis and inhibit cell proliferation,…”
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Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer by Wei, Shuo, Kozono, Shingo, Kats, Lev, Nechama, Morris, Li, Wenzong, Guarnerio, Jlenia, Luo, Manli, You, Mi-Hyeon, Yao, Yandan, Kondo, Asami, Hu, Hai, Bozkurt, Gunes, Moerke, Nathan J, Cao, Shugeng, Reschke, Markus, Chen, Chun-Hau, Rego, Eduardo M, Lo-Coco, Francesco, Cantley, Lewis C, Lee, Tae Ho, Wu, Hao, Zhang, Yan, Pandolfi, Pier Paolo, Zhou, Xiao Zhen, Lu, Kun Ping

“…All- trans retinoic acid binds to, inhibits and induces degradation of the active form of the prolyl isomerase Pin1, thereby turning off and on a variety of…”
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Fretting fatigue life of galvanized bridge support cable wire: Experimental study and strain-based fracture mechanics analysis by do Rêgo, Eduardo Martins Fontes, Chehrazi, Ali, Miranda, Antonio Carlos Oliveira, Walbridge, Scott, Topper, Tim

“…•Fretting fatigue behavior of galvanized wires was studied using strain-based fracture mechanics.•Point load weight functions for wires were developed to…”
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The legal paradox in the work of Eça de Queiroz: thoughts on the novels “O crime do padre Amaro” and “O primo Basílio” by Rêgo, Eduardo de Carvalho

“…This paper searches for one possible way of understanding the Law based on the novels "O crime do padre Amaro" and "O primo Basílio", by Portuguese writer Eça…”
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Temporal trends in Hematopoietic Stem Cell Transplantation in Argentina: regional differences that mirror the global reality by Rego, Eduardo M

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Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability by Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Geugien, Marjan, Cunningham, Alan, Pruis, Maurien G., Weinhäuser, Isabel, Gerding, Albert, Bakker, Barbara M., Wierenga, Albertus T. J., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob

“…Metabolic programs can differ substantially across genetically distinct subtypes of acute myeloid leukemia (AML). These programs are not static entities but…”
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IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells by Rodrigues Alves, Ana Paula Nunes, Fernandes, Jaqueline Cristina, Fenerich, Bruna Alves, Coelho-Silva, Juan Luiz, Scheucher, Priscila Santos, Simões, Belinda Pinto, Rego, Eduardo Magalhães, Ridley, Anne J., Machado-Neto, João Agostinho, Traina, Fabiola

“…The IGF1R/IRS1 signaling is activated in acute lymphoblastic leukemia (ALL) and can be targeted by the pharmacological inhibitors NT157 (IGF1R-IRS1/2…”
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Modeling dynamics and alternative treatment strategies in acute promyelocytic leukemia by Yoshinari, Jr, Gerson Hiroshi, Fassoni, Artur César, Mello, Luis Fernando, Rego, Eduardo M

“…Acute Promyelocytic Leukemia (APL) is a rare and potentially lethal condition in which risk-based therapy often leads to better outcomes. Because of its rarity…”
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Thiostrepton induces cell death of acute myeloid leukemia blasts and the associated macrophage population by Weinhäuser, Isabel, Pereira-Martins, Diego A, Hilberink, Jacobien R, Brouwers-Vos, Annet, Rego, Eduardo M, Huls, Gerwin, Schuringa, Jan Jacob

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The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia by Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Cortés, Roldán, Cunningham, Alan, Pruis, Maurien G., de Boer, Bauke, van den Heuvel, Fiona A. J., Geugien, Marjan, Wierenga, Albertus T. J., Brouwers-Vos, Annet Z., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob

“…Acute myeloid leukemia remains difficult to treat due to strong genetic heterogeneity between and within individual patients. Here, we show that Pyruvate…”
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A 4-gene prognostic index for enhancing acute myeloid leukaemia survival prediction by Ortiz Rojas, Cesar Alexander, Pereira-Martins, Diego Antonio, Bellido More, Candy Christie, Sternadt, Dominique, Weinhäuser, Isabel, Hilberink, Jacobien R, Coelho-Silva, Juan Luiz, Thomé, Carolina Hassibe, Ferreira, Germano Aguiar, Ammatuna, Emanuele, Huls, Gerwin, Valk, Peter J, Schuringa, Jan Jacob, Rego, Eduardo Magalhães

“…Despite advancements in utilizing genetic markers to enhance acute myeloid leukaemia (AML) outcome prediction, significant disease heterogeneity persists,…”
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Dietary methionine starvation impairs acute myeloid leukemia progression by Cunningham, Alan, Erdem, Ayşegül, Alshamleh, Islam, Geugien, Marjan, Pruis, Maurien, Pereira-Martins, Diego Antonio, van den Heuvel, Fiona A. J., Wierenga, Albertus T. J., ten Berge, Hilde, Dennebos, Robin, van den Boom, Vincent, Hogeling, Shanna M., Weinhäuser, Isabel, Knops, Ruth, de Blaauw, Pim, Heiner-Fokkema, M. Rebecca, Woolthuis, Carolien, Günther, Ulrich L., Rego, Eduardo M., Martens, Joost H. A., Jansen, Joop H., Schwalbe, Harald, Huls, Gerwin, Schuringa, Jan Jacob

“…•Amino acid dropout screen reveals that AML cells highly depend on methionine, cysteine, arginine, glutamine, and lysine.•Dietary methionine removal impacts on…”
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Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia by Lima, Keli, Nogueira, Frederico Lisboa, Cipelli, Marcella, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego Antonio, da Silva, Wellington Fernandes, Cavaglieri, Rita de Cássia, Nardinelli, Luciana, Leal, Aline de Medeiros, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Câmara, Niels Olsen Saraiva, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

“…Acute lymphoblastic leukemia (ALL), a complex malignancy, displays varying expression profiles of PIP4K2-related genes in adult patients. While PIP4K2A…”
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STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells by Vicari, Hugo Passos, Coelho-Silva, Juan Luiz, Pereira-Martins, Diego A., Lucena-Araujo, Antônio Roberto, Lima, Keli, Lipreri da Silva, Jean Carlos, Scheucher, Priscila Santos, Koury, Luisa C., de Melo, Raul A., Bittencourt, Rosane, Pagnano, Katia, Nunes, Elenaide, Fagundes, Evandro M., Kerbauy, Fabio, de Figueiredo-Pontes, Lorena Lobo, Costa-Lotufo, Leticia Veras, Rego, Eduardo Magalhães, Traina, Fabiola, Machado-Neto, João Agostinho

“…Summary Stathmin 1 (STMN1) is a microtubule-destabilizing protein highly expressed in hematological malignancies and involved in proliferation and…”
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Co-occurrence of DNMT3A, NPM1, FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis by Bezerra, Matheus F., Lima, Aleide S., Piqué-Borràs, Maria-Riera, Silveira, Douglas R., Coelho-Silva, Juan L., Pereira-Martins, Diego A., Weinhäuser, Isabel, Franca-Neto, Pedro L., Quek, Lynn, Corby, Anna, Oliveira, Mayara M., Lima, Marinus M., de Assis, Reijane A., de Melo Campos, Paula, Duarte, Bruno K., Bendit, Israel, Rocha, Vanderson, Rego, Eduardo M., Traina, Fabiola, Saad, Sara T., Beltrão, Eduardo I., Bezerra, Marcos A., Lucena-Araujo, Antonio R.

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