Search Results - "Rémi, J."

Cardiovascular adverse effects of phenytoin by Guldiken, B., Rémi, J., Noachtar, Soheyl

“…Phenytoin is an established drug in the treatment of acute repetitive seizures and status epilepticus. One of its main advantages over benzodiazepines is the…”
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Preclinical evaluation of a precision medicine approach to DNA vaccination in type 1 diabetes by Postigo-Fernandez, Jorge, Firdessa-Fite, Rebuma, Creusot, Rémi J

“…Antigen-specific immunotherapy involves the delivery of self-antigens as proteins or peptides (or using nucleic acids encoding them) to reestablish tolerance…”
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Altered Function of Antigen-Presenting Cells in Type 1 Diabetes: A Challenge for Antigen-Specific Immunotherapy? by Creusot, Rémi J, Postigo-Fernandez, Jorge, Teteloshvili, Nato

“…Type 1 diabetes (T1D) arises from a failure to maintain tolerance to specific β-cell antigens. Antigen-specific immunotherapy (ASIT) aims to reestablish immune…”
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Nanoparticles versus Dendritic Cells as Vehicles to Deliver mRNA Encoding Multiple Epitopes for Immunotherapy by Firdessa-Fite, Rebuma, Creusot, Rémi J.

“…The efficacy of antigen-specific immunotherapy relies heavily on efficient antigen delivery to antigen-presenting cells and engagement of as many…”
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A multi-epitope DNA vaccine enables a broad engagement of diabetogenic T cells for tolerance in Type 1 diabetes by Postigo-Fernandez, Jorge, Creusot, Rémi J.

“…Type 1 diabetes (T1D) is caused by diabetogenic T cells that evaded tolerance mechanisms and react against multiple β-cell antigens. Antigen-specific therapy…”
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Performance and clinical outcomes in telestroke remain robust during the COVID-pandemic: insight into the NEVAS network by Masouris, Ilias, Kellert, L., Müller, R., Fuhry, L., Hamann, G. F., Rémi, J. M., Schöberl, F.

“…Background The COVID-19 pandemic had significant impact on global healthcare, including stroke management. Telemedical stroke networks have emerged with…”
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Phenotypic alterations in pancreatic lymph node stromal cells from human donors with type 1 diabetes and NOD mice by Postigo-Fernandez, Jorge, Farber, Donna L., Creusot, Rémi J.

“…Aims/hypothesis Tolerance induction in lymph nodes can be mediated by both haematopoietic cells (e.g. specific dendritic cells subsets) and by…”
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It's time to bring dendritic cell therapy to type 1 diabetes by Creusot, Rémi J, Giannoukakis, Nick, Trucco, Massimo, Clare-Salzler, Michael J, Fathman, C Garrison

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Is obesity an independent prognosis factor in woman breast cancer? by Majed, Bilal, Moreau, Thierry, Senouci, Kamel, Salmon, Rémi J., Fourquet, Alain, Asselain, Bernard

“…Background Breast cancer and obesity represent important public health issues in most western countries. A number of studies found a negative prognosis effect…”
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Letter to the Editor: Announcement of a Call for Proposals for biomedical waveform coding by Halford, J.J., Campobello, G., Brinkmann, B.H., Stead, M., Rampp, S., Rémi, J., Nilsen, K.B., Dauwels, J., Galanti, M., Dean, B.C., Winkler, S., Ehrenberg, J.A., Pfaff, J., Sullivan, G.J.

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Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes by Collier, Ai-Ris, Sheng, Deqiao, Chang, Pearl, Creusot, Rémi J, Albert, Paul R, Su, Leon, Yip, Linda, Turley, Shannon J, Czesak, Margaret, Atkinson, Mark, Fathman, C Garrison

“…Expression of peripheral tissue antigens may be important for peripheral T cell tolerance. Fathman and colleagues demonstrate involvement of the transcription…”
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Humanized Mice Reveal New Insights Into the Thymic Selection of Human Autoreactive CD8 + T Cells by Li, Yang, Teteloshvili, Nato, Tan, Shulian, Rao, Samhita, Han, Arnold, Yang, Yong-Guang, Creusot, Rémi J

“…Thymic selection constitutes the first checkpoint in T-cell development to purge autoreactive T cells. Most of our understanding of this process comes from…”
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Congruence and discrepancy of interictal and ictal EEG with MRI lesions in focal epilepsies by REMI, J, VOLLMAR, C, DE MARINIS, A, HEINLIN, J, PERAUD, A, NOACHTAR, S

“…To compare the occurrence and localization of interictal epileptiform discharges (IEDs) and epileptic seizure patterns (ESPs) with the localization of MRI…”
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Impact of withdrawal of antiepileptic medication on the duration of focal onset seizures by Hartl, E., Seethaler, M., Lauseker, M., Rémi, J., Vollmar, C., Noachtar, S.

“…•analysis of 672 focal onset seizures with intracranial EEG recording.•seizure rebound effect was observed after rapid AED withdrawal.•seizures did not prolong…”
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What is the “L” in LPDs? Localized as well as lateralized by Hartl, E., Rémi, J., Stoyke, C., Noachtar, S.

“…Background Periodic discharges (PDs) are well established as either periodic lateralized epileptiform discharges (LPDs) or generalized discharges. However, PDs…”
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Standard procedures for the diagnostic pathway of sleep‐related epilepsies and comorbid sleep disorders: an EAN, ESRS and ILAE‐Europe consensus review by Nobili, L., Weerd, A., Rubboli, G., Beniczky, S., Derry, C., Eriksson, S., Halasz, P., Högl, B., Santamaria, J., Khatami, R., Ryvlin, P., Rémi, J., Tinuper, P., Bassetti, C., Manni, R., Koutroumanidis, M., Vignatelli, L.

“…Background and purpose Some epilepsy syndromes (sleep‐related epilepsies, SREs) have a strong link with sleep. Comorbid sleep disorders are common in patients…”
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Initiating type I diabetes: new suspects in the lineup by Creusot, Rémi J

“…Several physiological and pathological events taking place postnatally in or around the pancreatic islets of Langerhans have been implicated in the initiation…”
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Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge by Rhrissorrakrai, Kahn, Belcastro, Vincenzo, Bilal, Erhan, Norel, Raquel, Poussin, Carine, Mathis, Carole, Dulize, Rémi H J, Ivanov, Nikolai V, Alexopoulos, Leonidas, Rice, J Jeremy, Peitsch, Manuel C, Stolovitzky, Gustavo, Meyer, Pablo, Hoeng, Julia

“…Inferring how humans respond to external cues such as drugs, chemicals, viruses or hormones is an essential question in biomedicine. Very often, however, this…”
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NF-κB in DCs: it takes effort to be immature by Creusot, Rémi J

“…The nuclear factor-κB (NF-κB) family of regulators is well known for mediating dendritic cell (DC) maturation—that is, the acquisition of the functions…”
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Quantitative and qualitative analysis of ictal vocalization in focal epilepsy syndromes by Hartl, E., Knoche, T., Choupina, H.M.P., Rémi, J., Vollmar, C., Cunha, J.P.S, Noachtar, S.

“…•Ictal vocalization occurs in nearly 40% of focal seizures.•It increases the localizing value of automatisms.•Vocalization during automatisms identifies…”
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