Localized scleroderma: a retrospective study about 92 cases

Sclerodermas are rare affections which can be located or generalized. Localized form is the most frequent. The purpose of this study was to describe epidemiologic, clinics, biological, immunological, therapeutic, evolutionary characteristics of the localized scleroderma through a personal series and...

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Bibliographic Details
Published in:	Tunisie Medicale Vol. 87; no. 9; p. 573
Main Authors:	El Fékih, Nadia, Réjaibi, Iménc, Kamoun, Hajer, Zéglaoui, Faten, Fazaa, Bécima, Kharfi, Monia, Kamoun, Mohamed Ridha
Format:	Journal Article
Language:	French
Published:	Tunisia 01-09-2009
Subjects:	Adolescent Adrenal Cortex Hormones - therapeutic use Adult Age Factors Aged Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - therapeutic use Child Child, Preschool Female Glucocorticoids - administration & dosage Glucocorticoids - therapeutic use Humans Male Middle Aged Prednisone - administration & dosage Prednisone - therapeutic use Retrospective Studies Scleroderma, Localized - complications Scleroderma, Localized - diagnosis Scleroderma, Localized - drug therapy Scleroderma, Localized - epidemiology Time Factors
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Summary:	Sclerodermas are rare affections which can be located or generalized. Localized form is the most frequent. The purpose of this study was to describe epidemiologic, clinics, biological, immunological, therapeutic, evolutionary characteristics of the localized scleroderma through a personal series and the data of the literature. We have performed a retrospective study on all patients followed in the department of dermatology of the Hospital Charles Nicole during 14 years period. Our study was about 92 cases of localized scleroderma (73 were females and 19 males). The mean age was 35 years (between 2 and 72 years). The majority of localised sclerodermas (66.2% of the cases) appeared before 40 years with a maximum of frequency between 10 and 30 years (41.6%). Only 11.9% of the cases were observed before 10 years. They were 51 cases (55%) of morphea, 35 cases (38%) of scleroderma in bands including 32 linear scleroderma and 3 scleroderma en coup de sabre, 5 cases (5.5%) of generalized morphea and 1 case (0.15%) of deep morphea. Average therapeutic was specified among 63 patients (87%), and the evolution could be appreciated among 45 patients. The epidemiologic data observed in our series are comparable with those reported in the literature. Therapeutic difficulties and risks of functional after-effects, particular in scleroderma in bands, remain the principal concern for all the authors.
ISSN:	0041-4131