Search Results - "Régner, Sara"

Is less more? Challenging dogma for individualized fluid resuscitation by Regnér, Sara

“…New data suggest that moderate fluid resuscitation is safer in acute pancreatitis than the standard aggressive fluid resuscitation. The findings suggest that…”
Get full text

Long-Term Follow-up and Risk of Recurrence of Internal Herniation after Roux-en-Y Gastric Bypass by Zaigham, Hassan, Ekelund, Mikael, Regnér, Sara

“…Purpose Internal herniation (IH) is the most common complication after Roux-en-Y gastric bypass surgery (RYGB). Although primary closure has reduced the…”
Get full text

Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute Pancreatitis by Merza, Mohammed, Hartman, Hannes, Rahman, Milladur, Hwaiz, Rundk, Zhang, Enming, Renström, Erik, Luo, Lingtao, Mörgelin, Matthias, Regner, Sara, Thorlacius, Henrik

“…Background & Aims Neutrophils are involved in the development of acute pancreatitis (AP), but it is not clear how neutrophil-induced tissue damage is…”
Get full text

Intussusception After Roux-en-Y Gastric Bypass: Correlation Between Radiological and Operative Findings by Zaigham, Hassan, Ekelund, Mikael, Lee, Daisy, Ekberg, Olle, Regnér, Sara

“…Introduction Intussusceptions diagnosed on computed tomography (CT) scans in Roux-en-Y gastric bypass (RYGB) patients could cause serious small bowel…”
Get full text

Differences in Health-Related Quality of Life After Gastric Bypass Surgery: a Cross-Sectional Study by Antonsson, Tobias, Wennersten, André, Sörensen, Kaisa, Regnér, Sara, Ekelund, Mikael

“…Background Gastric bypass (GBP) is a surgical method with good evidence of sustainable weight loss, reduced obesity-related comorbidities, and improved…”
Get full text

Role of neutrophils in the activation of trypsinogen in severe acute pancreatitis by Abdulla, Aree, Awla, Darbaz, Thorlacius, Henrik, Regnér, Sara

“…Initial trypsinogen activation is independent of neutrophils whereas later activation is dependent on neutrophils. The relationship between inflammation and…”
Get full text

The Initial Course of IL1β, IL-6, IL-8, IL-10, IL-12, IFN-γ and TNF-α with Regard to Severity Grade in Acute Pancreatitis by Sternby, Hanna, Hartman, Hannes, Thorlacius, Henrik, Regnér, Sara

“…Clinical reports on early immune dysregulation in acute pancreatitis (AP) are scarce. Herein we investigate the initial temporal development of selected…”
Get full text

IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality by Zhang, Hong, Neuhöfer, Patrick, Song, Liang, Rabe, Björn, Lesina, Marina, Kurkowski, Magdalena U, Treiber, Matthias, Wartmann, Thomas, Regnér, Sara, Thorlacius, Henrik, Saur, Dieter, Weirich, Gregor, Yoshimura, Akihiko, Halangk, Walter, Mizgerd, Joseph P, Schmid, Roland M, Rose-John, Stefan, Algül, Hana

“…Acute lung injury (ALI) is an inflammatory disease with a high mortality rate. Although typically seen in individuals with sepsis, ALI is also a major…”
Get full text

Laparoscopic transcystic common bile duct exploration versus transgastric endoscopic retrograde cholangiography during cholecystectomy after Roux-en-Y gastric bypass by Zaigham, Hassan, Enochsson, Lars, Ottosson, Johan, Regnér, Sara

“…Treatment of common bile duct (CBD) stones after Roux-en-Y gastric bypass (RYGB) poses a particular challenge given the altered anatomy and inability to…”
Get full text

Fatty liver disease and pancreatic inflammation—A lethal combination? by Regnér, Sara, Önnerhag, Kristina, Sternby, Hanna

“…For patients with moderate or severe AP, fast and efficient treatment of complications is a prerequisite to keep mortality as well as long-term morbidity…”
Get full text

Abdominal pain after gastric bypass in the acute general surgical care setting by Zaigham, Hassan, Ekelund, Mikael, Regnér, Sara, Olsson, Åsa

“…Managing acute abdominal pain in the large and growing population of Roux-en-Y gastric bypass (RYGB)–operated patients poses a challenge to general surgeons,…”
Get full text

IL-6 and CRP are superior in early differentiation between mild and non-mild acute pancreatitis by Sternby, Hanna, Hartman, Hannes, Johansen, Dorthe, Thorlacius, Henrik, Regnér, Sara

“…Abstract Background The revised Atlanta classification on acute pancreatitis (AP) presents distinct criteria for severity categorization. Due to the lack of…”
Get full text

Heparin-binding protein is significantly increased in acute pancreatitis by Sjöbeck, Martina, Sternby, Hanna, Herwald, Heiko, Thorlacius, Henrik, Regnér, Sara

“…Abstract Background Most patients with acute pancreatitis (AP) experience mild, self-limiting disease with little or no need for hospital care. However, 20–25%…”
Get full text

The role of citrulline, intestinal fatty acid–binding protein, and D-dimer as potential biomarkers in the diagnosis of internal herniation after Roux-en-Y gastric bypass by Zaigham, Hassan, Olsson Regnér, Åsa, Ekelund, Mikael, Regnér, Sara

“…Diagnosing internal herniation (IH) in Roux-en-Y gastric bypass (RYGB) patients with acute abdominal pain poses a diagnostic challenge. Diagnostic laparoscopy…”
Get full text

Postoperative three-dimensional endoanal ultrasound findings and relation to anal fistula plug failure by Aho Fält, Ursula, Zawadzki, Antoni, Starck, Marianne, Bohe, Måns, Regnér, Sara, Johnson, Louis B.

“…To explore the utilization of three-dimensional (3D) endoanal ultrasound (EAUS) for the follow-up of the anal fistula plug (AFP), describe morphological…”
Get full text

TLR4 but not TLR2 regulates inflammation and tissue damage in acute pancreatitis induced by retrograde infusion of taurocholate by Awla, Darbaz, Abdulla, Aree, Regnér, Sara, Thorlacius, Henrik

“…Objective Neutrophil infiltration is a key regulator in the pathophysiology of acute pancreatitis (AP), although the impact of Toll-like receptors (TLRs) in AP…”
Get full text

Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis by Awla, Darbaz, Abdulla, Aree, Syk, Ingvar, Jeppsson, Bengt, Regnér, Sara, Thorlacius, Henrik

“…Neutrophil‐derived MMP‐9 regulates trypsinogen activation, pathological inflammation, and tissue damage in acute pancreatitis. MMPs are generally considered to…”
Get full text

Human thrombin-derived host defense peptides inhibit neutrophil recruitment and tissue injury in severe acute pancreatitis by Merza, Mohammed, Rahman, Milladur, Zhang, Songen, Hwaiz, Rundk, Regner, Sara, Schmidtchen, Artur, Thorlacius, Henrik

“…Severe acute pancreatitis (AP) is characterized by leukocyte infiltration and tissue injury. Herein, we wanted to examine the potential effects of…”
Get more information

Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice by Hartman, Hannes, Wetterholm, Erik, Thorlacius, Henrik, Regnér, Sara

“…Background The onset of acute pancreatitis (AP) is characterized by early protease activation followed by inflammation and organ damage, but the mechanisms are…”
Get full text

NFATc3 Regulates Trypsinogen Activation, Neutrophil Recruitment, and Tissue Damage in Acute Pancreatitis in Mice by Awla, Darbaz, Zetterqvist, Anna V, Abdulla, Aree, Camello, Cristina, Berglund, Lisa M, Spégel, Peter, Pozo, Maria J, Camello, Pedro J, Regnér, Sara, Gomez, Maria F, Thorlacius, Henrik

“…Background & Aims The signaling mechanisms that regulate trypsinogen activation and inflammation in acute pancreatitis (AP) are unclear. We explored the…”
Get full text