Search Results - "Räder, Andreas"

Synthetic extracellular matrices with tailored adhesiveness and degradability support lumen formation during angiogenic sprouting by Liu, Jifeng, Long, Hongyan, Zeuschner, Dagmar, Räder, Andreas F. B., Polacheck, William J., Kessler, Horst, Sorokin, Lydia, Trappmann, Britta

“…A major deficit in tissue engineering strategies is the lack of materials that promote angiogenesis, wherein endothelial cells from the host vasculature invade…”
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Orally Active Peptides: Is There a Magic Bullet? by Räder, Andreas F. B., Weinmüller, Michael, Reichart, Florian, Schumacher‐Klinger, Adi, Merzbach, Shira, Gilon, Chaim, Hoffman, Amnon, Kessler, Horst

“…For decades, the development of peptides as potential drugs was aimed solely at peptides with the highest affinity, receptor selectivity, or stability against…”
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Improving oral bioavailability of cyclic peptides by N-methylation by Räder, Andreas F.B., Reichart, Florian, Weinmüller, Michael, Kessler, Horst

“…[Display omitted] The renaissance of peptides in pharmaceutical industry results from their importance in many biological functions. However, low metabolic…”
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Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin by Han, Jiaying, Räder, Andreas F. B, Reichart, Florian, Aikman, Brech, Wenzel, Margot N, Woods, Ben, Weinmüller, Michael, Ludwig, Beatrice S, Stürup, Stefan, Groothuis, Geny M. M, Permentier, Hjalmar P, Bischoff, Rainer, Kessler, Horst, Horvatovich, Peter, Casini, Angela

“…Cisplatin occupies a crucial role in the treatment of various malignant tumors. However, its efficacy and applicability are heavily restricted by severe…”
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Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway by Schumacher-Klinger, Adi, Fanous, Joseph, Merzbach, Shira, Weinmüller, Michael, Reichart, Florian, Räder, Andreas F. B, Gitlin-Domagalska, Agata, Gilon, Chaim, Kessler, Horst, Hoffman, Amnon

“…Hydrophilic peptides constitute most of the active peptides. They mostly permeate via tight junctions (paracellular pathway) in the intestine. This…”
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Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide by Reichart, Florian, Maltsev, Oleg V, Kapp, Tobias G, Räder, Andreas F. B, Weinmüller, Michael, Marelli, Udaya Kiran, Notni, Johannes, Wurzer, Alexander, Beck, Roswitha, Wester, Hans-Jürgen, Steiger, Katja, Di Maro, Salvatore, Di Leva, Francesco Saverio, Marinelli, Luciana, Nieberler, Markus, Reuning, Ute, Schwaiger, Markus, Kessler, Horst

“…Integrins play important roles in physiological and pathophysiological processes. Among the RGD-recognizing integrin subtypes, the αvβ8 receptor is emerging as…”
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Exploring the Role of RGD-Recognizing Integrins in Cancer by Nieberler, Markus, Reuning, Ute, Reichart, Florian, Notni, Johannes, Wester, Hans-Jürgen, Schwaiger, Markus, Weinmüller, Michael, Räder, Andreas, Steiger, Katja, Kessler, Horst

“…Integrins are key regulators of communication between cells and with their microenvironment. Eight members of the integrin superfamily recognize the tripeptide…”
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Tertiary Alcohols as Substrates for SN2-Like Stereoinversion by Räder, Andreas F. B., Tiefenbacher, Konrad

“…Rewrite the textbooks! The stereospecific bimolecular substitution reaction (SN2) is usually limited to primary and secondary electrophiles. The Shenvi group…”
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Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3 by Weinmüller, Michael, Rechenmacher, Florian, Kiran Marelli, Udaya, Reichart, Florian, Kapp, Tobias G., Räder, Andreas F. B., Di Leva, Francesco Saverio, Marinelli, Luciana, Novellino, Ettore, Muñoz‐Félix, José M., Hodivala‐Dilke, Kairbaan, Schumacher, Adi, Fanous, Joseph, Gilon, Chaim, Hoffman, Amnon, Kessler, Horst

“…A highly systematic approach for the development of both orally bioavailable and bioactive cyclic N‐methylated hexapeptides as high affinity ligands for the…”
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Materials Acceleration Platforms (MAPs): Accelerating Materials Research and Development to Meet Urgent Societal Challenges by Stier, Simon P., Kreisbeck, Christoph, Ihssen, Holger, Popp, Matthias Albert, Hauch, Jens, Malek, Kourosh, Reynaud, Marine, Goumans, T.P.M., Carlsson, Johan, Todorov, Ilian, Gold, Lukas, Räder, Andreas, Wenzel, Wolfgang, Bandesha, Shahbaz Tareq, Jacques, Philippe, Garcia‐Moreno, Francisco, Arcelus, Oier, Friederich, Pascal, Clark, Simon, Maglione, Mario, Laukkanen, Anssi, Castelli, Ivano Eligio, Carrasco, Javier, Cabanas, Montserrat Casas, Stein, Helge Sören, Ozcan, Ozlem, Elbert, David, Reuter, Karsten, Scheurer, Christoph, Demura, Masahiko, Han, Sang Soo, Vegge, Tejs, Nakamae, Sawako, Fabrizio, Monica, Kozdras, Mark

“…Climate Change and Materials Criticality challenges are driving urgent responses from global governments. These global responses drive policy to achieve…”
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N -Methylation of iso DGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent by Kapp, Tobias G., Di Leva, Francesco Saverio, Notni, Johannes, Räder, Andreas F. B., Fottner, Maximilian, Reichart, Florian, Reich, Dominik, Wurzer, Alexander, Steiger, Katja, Novellino, Ettore, Marelli, Udaya Kiran, Wester, Hans-Jürgen, Marinelli, Luciana, Kessler, Horst

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N‑Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent by Kapp, Tobias G, Di Leva, Francesco Saverio, Notni, Johannes, Räder, Andreas F. B, Fottner, Maximilian, Reichart, Florian, Reich, Dominik, Wurzer, Alexander, Steiger, Katja, Novellino, Ettore, Marelli, Udaya Kiran, Wester, Hans-Jürgen, Marinelli, Luciana, Kessler, Horst

“…Specific targeting of the integrin subtype α5β1 possesses high potential in cancer diagnosis and therapy. Through sequential N-methylation, we successfully…”
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Tertiäre Alkohole als Substrate für eine SN2-artige Stereoinversion by Räder, Andreas F. B., Tiefenbacher, Konrad

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Tertiary Alcohols as Substrates for S N 2‐Like Stereoinversion by Räder, Andreas F. B., Tiefenbacher, Konrad

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Oral aktive Peptide: Gibt es ein Patentrezept? by Räder, Andreas F B, Weinmüller, Michael, Reichart, Florian, Adi Schumacher‐Klinger, Merzbach, Shira, Gilon, Chaim, Hoffman, Amnon, Kessler, Horst

“…Die Entwicklung von Peptiden als potentielle Medikamente zielte über Jahrzehnte einzig darauf ab, höchste Affinitäten, Rezeptorselektivitäten oder Stabilität…”
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Tertiary alcohols as substrates for S(N)2-like stereoinversion by Räder, Andreas F B, Tiefenbacher, Konrad

“…Rewrite the textbooks! The stereospecific bimolecular substitution reaction (SN 2) is usually limited to primary and secondary electrophiles. The Shenvi group…”
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Tertiäre Alkohole als Substrate für eine SN2‐artige Stereoinversion by Räder, Andreas F. B., Tiefenbacher, Konrad

“…Komplett entgegengesetzt zur klassischen SN2‐Reaktivität verläuft die von der Shenvi‐Gruppe vorgestellte Methode, um tertiäre Alkohole in Isocyanide mit…”
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Lösung des Problems mangelnder oraler Verfügbarkeit cyclischer Hexapeptide: Entwicklung eines selektiven, oral verfügbaren Liganden für das Integrin αvβ3 by Weinmüller, Michael, Rechenmacher, Florian, Kiran Marelli, Udaya, Reichart, Florian, Kapp, Tobias G., Räder, Andreas F. B., Di Leva, Francesco Saverio, Marinelli, Luciana, Novellino, Ettore, Muñoz‐Félix, José M., Hodivala‐Dilke, Kairbaan, Schumacher, Adi, Fanous, Joseph, Gilon, Chaim, Hoffman, Amnon, Kessler, Horst

“…Ein systematischer Ansatz für die Entwicklung oral verfügbarer wie auch biologisch aktiver, cyclischer, N‐methylierter Hexapeptide als hoch affine Liganden für…”
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Oral aktive Peptide: Gibt es ein Patentrezept? by Räder, Andreas F. B., Weinmüller, Michael, Reichart, Florian, Schumacher‐Klinger, Adi, Merzbach, Shira, Gilon, Chaim, Hoffman, Amnon, Kessler, Horst

“…Die Entwicklung von Peptiden als potentielle Medikamente zielte über Jahrzehnte einzig darauf ab, höchste Affinitäten, Rezeptorselektivitäten oder Stabilität…”
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Tertiäre Alkohole als Substrate für eine S N 2‐artige Stereoinversion by Räder, Andreas F. B., Tiefenbacher, Konrad

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