Search Results - "R, Seegmiller"

Losartan attenuates progression of osteoarthritis in the synovial temporomandibular and knee joints of a chondrodysplasia mouse model through inhibition of TGF-β1 signaling pathway by Thomas, M., Fronk, Z., Gross, A., Willmore, D., Arango, A., Higham, C., Nguyen, V., Lim, H., Kale, V., McMillan, G., Seegmiller, R.E.

“…Transforming growth factor beta 1 (TGF-β1) is implicated in osteoarthritis (OA). The purpose of this study was to explore the ability of Losartan to inhibit…”
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Addressing Frequent Issues of Home Enteral Nutrition Patients by Johnson, Teresa W., RN, Sara Seegmiller, Epp, Lisa, Mundi, Manpreet S.

“…The home enteral nutrition (HEN) population is a medically diverse group whose number has increased substantially in recent decades. Although medically stable…”
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The Role of TGF-ß1 in Osteoarthritis of the Temporomandibular Joint in Two Genetic Mouse Models by Long, E, Motwani, R, Reece, D, Pettit, N, Hepworth, J, Wong, P, Reynolds, P, Seegmiller, R

“…Highlights • The pathogenesis of Temporomandibular Joint (TMJ) Osteoarthritis (OA) is molecular. • TGF-ß1 plays a role in the molecular signaling pathway…”
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Osteoarthritis-like changes in the heterozygous sedc mouse associated with the HtrA1–Ddr2–Mmp-13 degradative pathway: a new model of osteoarthritis by Holt, D.W, Henderson, M.L, Stockdale, C.E, Farrell, J.T, Kooyman, D.L, Bridgewater, L.C, Seegmiller, R.E

“…Summary Objective To test the hypothesis that the spondyloepiphyseal dysplasia congenita ( sedc ) heterozygous ( sedc /+) mouse, a COL2A1 mutant, is a model…”
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Osteoarthritis in temporomandibular joint of Col2a1 mutant mice by Ricks, M.L, Farrell, J.T, Falk, D.J, Holt, D.W, Rees, M, Carr, J, Williams, T, Nichols, B.A, Bridgewater, L.C, Reynolds, P.R, Kooyman, D.L, Seegmiller, R.E

“…Abstract Objective Col2a1 gene mutations cause premature degeneration of knee articular cartilage in disproportionate micromelia ( Dmm ) and spondyloepiphesial…”
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133 PATHOGENESIS OF OSTEOARTHRITIS IN THE SEDC HETEROZYGOUS MOUSE: A NEW ANIMAL MODEL by Holt, D, Henderson, M, Seegmiller, R

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Premature osteoarthritis in the Disproportionate micromelia ( Dmm) mouse by Bomsta, B.D., Bridgewater, L.C., Seegmiller, R.E.

“…Degeneration of articular cartilage leads to the development of osteoarthritis (OA), but the molecular pathology of the disease is poorly understood. The…”
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A type XI collagen mutation leads to increased degradation of type II collagen in articular cartilage by Rodriguez, R.R., Seegmiller, R.E., Stark, M.R., Bridgewater, L.C.

“…Objective: To determine in articular cartilage whether degraded type II collagen is more abundant in Col11a1 mutant cho/+ than in age-matched +/+ mice and…”
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A-60 The Armed Services Vocational Aptitude Battery and Premorbid Intellectual Functioning by Trahan, E, Good, D, Seegmiller, R

“…Abstract Objective The objective of this study is to evaluate correlations between the Armed Services Vocational Aptitude Battery (ASVAB) with other measures…”
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A-224 Clinical Utility of Grooved Pegboard as an Additional Embedded Measure of Performance Validity by J, Link, L, Lu, P, Armistead-Jehle, R, Seegmiller

“…Abstract Objective Previously, the Grooved Pegboard Test (GPB) has shown potential as an embedded measure of performance validity (PVT) using a T-score cutoff…”
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A-75 Predicting neurocognitive impairment using the Green’s Medical Symptom Validity Test dementia profile formula by Ringdahl, E, Seegmiller, R, Aden, J, Stephens, C

“…Abstract Objective The Green’s Medical Symptom Validity Test (MSVT) is a measure of performance validity and has a formula to help distinguish genuine…”
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A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis by Li, Y, Lacerda, D.A, Warman, M.L, Beier, D.R, Yoshioka, H, Ninomiya, Y, Oxford, J.T, Morris, N.P, Andrikopoulos, K, Ramirez, F, Wardell, B.B, Lifferth, G.D, Teuscher, C, Woodward, S.R, Taylor, B.A, Seegmiller, R.E, Olsen, B.R

“…Mice that are homozygous for the autosomal recessive chondrodysplasia ( cho) mutation die at birth with abnormalities in cartilage of limbs, ribs, mandible,…”
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A-144 Mild Traumatic Brain Injury and Sleep Disturbances in Military Service Members as Predictors of Days Missed from Duty by J, Higa, L, Lu, M, Reid, B, Khokhar, R, Seegmiller, J, Kennedy

“…Abstract Objective Duty-limiting pain impacts military readiness. Conditions such as mild traumatic brain injury (mTBI), stress-related disorders (Acute Stress…”
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A-228 Are Those Who Fail Performance Validity Measures High Utilizers of Healthcare? by C, Cooper, E, Trahan, C, Muncy, J, Higa, J, Link, M, Reid, R, Seegmiller, J, Kennedy, L, Lu

“…Abstract Objective One study reported that suboptimal effort on performance validity tests (PVTs) is associated with higher healthcare utilization within a VA…”
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A developmental toxicity study of tretinoin administered topically and orally to pregnant Wistar rats by Seegmiller, Robert E., Ford, William H., Carter, Melvin W., Mitala, Joseph J., Powers, William J.

“…Background: Although it is well established that oral tretinoin produces embryofetal developmental toxicity in various laboratory animals, the toxic potential…”
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The mechanism of palatal clefting in the Col11a1 mutant mouse by Lavrin, Igor O, McLean, William, Seegmiller, Robert E, Olsen, Bjorn R, Hay, Elizabeth D

“…The occurrence of cleft palate in mutant mice offers an opportunity to understand the possible role of specific genes in palatogenesis. Here, cleft palate in…”
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Comparative developmental dermal toxicity and mutagenicity of carbazole and benzo[a]carbazole by Dutson, Sheryl M., Booth, Gary M., Schaalje, G. Bruce, Castle, Raymond N., Seegmiller, Robert E.

“…The objectives of this study were (1) to determine the developmental toxicity of carbazole and benzo[a]carbazole following daily dermal administration to…”
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Disproportionate micromelia (Dmm) in mice caused by a mutation in the C‐propeptide coding region of Col2a1 by Pace, James M., Li, Yefu, Seegmiller, Robert E., Teuscher, Cory, Taylor, Benjamin A., Olsen, Bjorn R.

“…Mice that are homozygous for the autosomal semidominant disproportionate micromelia (Dmm) mutation are characterized by disproportionate micromelia, thoracic…”
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Teaching an Undergraduate Course on Intrafamily Abuse across the Life Span by Seegmiller, Bonnie R

“…Describes an undergraduate course dealing with intrafamily abuse across the life span. Discusses the course format, including class discussions, lectures,…”
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Effect of PCB and DES on rat monoamine oxidase, acetylcholinesterase, testosterone, and estradiol ontogeny by Vincent, D R, Bradshaw, W S, Booth, G M, Seegmiller, R E, Allen, S D

“…Pregnant rats were exposed to either diethylstilbestrol (DES) or 3,3',4,4'-tetrachlorobiphenyl congener (4-CB) to determine the effects on monamine oxidase…”
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